Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.44 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.44 |
| ▸ | NMT2 | O60551 | 1/20 | 0.44 |
| ▸ | NMT1 | P30419 | 1/20 | 0.44 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.40 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.39 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.39 |
| ▸ | CTSC | P53634 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | GSTK1 | Q9Y2Q3 | 1/20 | 0.39 |
| ▸ | CPB2 | Q96IY4 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | TLR2 | O60603 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29590365 | 0.90 | SIRT6 (0.45) | SIRT6SIRT1NMT2NMT1FOLH1 | |
| SCHEMBL31099442 | 0.87 | SIRT6 (0.47) | SIRT6SIRT1NMT2NMT1FOLH1 | |
| SCHEMBL29531200 | 0.87 | SIRT6 (0.47) | SIRT6SIRT1NMT2NMT1FOLH1 | |
| SCHEMBL30272513 | 0.87 | SIRT6 (0.45) | SIRT6SIRT1NMT2NMT1FOLH1 | |
| SCHEMBL29714775 | 0.86 | NMT2 (0.44) | SIRT6SIRT1NMT2NMT1FOLH1 | |
| SCHEMBL21437116 | 0.86 | NMT2 (0.44) | SIRT6SIRT1NMT2NMT1FOLH1 | |
| SCHEMBL29630356 | 0.85 | FOLH1 (0.50) | NMT2NMT1FOLH1CTSCCPB2 | |
| SCHEMBL24130548 | 0.84 | FOLH1 (0.53) | FOLH1CTSCCPB2 | |
| SCHEMBL8759318 | 0.84 | FOLH1 (0.53) | FOLH1CTSCCPB2 | |
| SCHEMBL8759327 | 0.84 | FOLH1 (0.53) | FOLH1CTSCCPB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 76 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4569002-A2 | PROTEINS BINDING NKG2D, CD16, AND CEACAM5 | Merck Sharp & Dohme LLC (US) | 2025-06-18 | — | — | EP | claimed |
| CN-119923412-A | Proteins binding to NKG2D, CD and CEACAM5 | 默沙东有限责任公司 | 2025-05-02 | — | — | CN | claimed |
| US-20240360223-A1 | PROTEINS BINDING NKG2D, CD16 AND BAFF-R | DRAGONFLY THERAPEUTICS INC (US) | 2024-10-31 | — | — | US | claimed |
| US-20240270861-A1 | PROTEINS BINDING NKG2D, CD16 AND BAFF-R | DRAGONFLY THERAPEUTICS INC (US) | 2024-08-15 | — | — | US | claimed |
| EP-4408896-A1 | PROTEINS BINDING NKG2D, CD16 AND BAFF-R | Dragonfly Therapeutics, Inc. (US) | 2024-08-07 | — | — | EP | claimed |
| CN-117964773-A | Multispecific binding proteins and improvements therein | 蜻蜓疗法股份有限公司 | 2024-05-03 | — | — | CN | claimed |
| WO-2023056252-A9 | PROTEINS BINDING NKG2D, CD16 AND BAFF-R | DRAGONFLY THERAPEUTICS, INC. (US) | 2024-05-02 | — | — | WO | claimed |
| US-20240124607-A1 | PROTEINS BINDING NKG2D, CD16, AND CEACAM5 | DRAGONFLY THERAPEUTICS, INC. | 2024-04-18 | — | — | US | claimed |
| US-20240117054-A1 | PROTEINS BINDING NKG2D, CD16 AND FLT3 | DRAGONFLY THERAPEUTICS, INC. | 2024-04-11 | — | — | US | claimed |
| CN-117730096-A | Proteins that bind NKG2D, CD16 and EGFR | 蜻蜓疗法股份有限公司 | 2024-03-19 | — | — | CN | claimed |
| US-20230257467-A1 | PROTEINS BINDING NKG2D, CD16 AND EGFR | DRAGONFLY THERAPEUTICS INC (US) | 2023-08-17 | — | — | US | claimed |
| US-20230203202-A1 | PROTEINS BINDING NKG2D, CD16 AND 5T4 | DRAGONFLY THERAPEUTICS INC (US) | 2023-06-29 | — | — | US | claimed |
| WO-2023107956-A1 | PROTEINS BINDING NKG2D, CD16 AND 5T4 | DRAGONFLY THERAPEUTICS, INC. (US) | 2023-06-15 | — | — | WO | claimed |
| EP-4192872-A1 | PROTEINS BINDING NKG2D, CD16 AND EGFR | Dragonfly Therapeutics, Inc. (US) | 2023-06-14 | — | — | EP | claimed |
| CN-115836088-A | NKG 2D-, CD 16-and CLEC 12A-binding proteins | 蜻蜓疗法股份有限公司 | 2023-03-21 | — | — | CN | claimed |
| EP-4146271-A1 | PROTEINS BINDING NKG2D, CD16 AND CLEC12A | Dragonfly Therapeutics, Inc. (US) | 2023-03-15 | — | — | EP | claimed |
| CN-115298217-A | NKG2D, CD and FLT3 binding protein | 蜻蜓疗法股份有限公司 | 2022-11-04 | — | — | CN | claimed |
| EP-4045538-A1 | PROTEINS BINDING NKG2D, CD16 AND FLT3 | Dragonfly Therapeutics, Inc. (US) | 2022-08-24 | — | — | EP | claimed |
| US-20220119534-A1 | PROTEINS BINDING NKG2D, CD16 AND CLEC12A | DRAGONFLY THERAPEUTICS, INC. | 2022-04-21 | — | — | US | claimed |
| WO-2022031965-A1 | PROTEINS BINDING NKG2D, CD16 AND EGFR | DRAGONFLY THERAPEUTICS, INC. (US) | 2022-02-10 | — | — | WO | claimed |