SCHEMBL29714775

SCHEMBL29714775

CC(C)[C@H](N)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)NCC(=O)O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ NMT2 O60551 1/20 0.44
▸ NMT1 P30419 1/20 0.44
▸ SIRT6 Q8N6T7 1/20 0.41
▸ SIRT1 Q96EB6 1/20 0.41
▸ GLO1 Q04760 1/20 0.40
▸ PTGS1 P23219 1/20 0.39
▸ GSTK1 Q9Y2Q3 1/20 0.39
▸ FOLH1 Q04609 1/20 0.38
▸ ITGB3 P05106 1/20 0.38
▸ ITGA2B P08514 1/20 0.38
▸ DPP4 P27487 2/20 0.37
▸ DPP8 Q6V1X1 2/20 0.37
▸ DPP9 Q86TI2 2/20 0.37
▸ DPP7 Q9UHL4 2/20 0.37
▸ FAP Q12884 1/20 0.37
▸ CPB2 Q96IY4 2/20 0.36
▸ SLC6A5 Q9Y345 1/20 0.36
▸ FURIN P09958 1/20 0.36
▸ ALDH1A1 P00352 1/20 0.36
▸ LMNA P02545 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21437116 1.00 NMT2 (0.44) NMT2NMT1SIRT6SIRT1GLO1
SCHEMBL29590365 0.95 SIRT6 (0.45) NMT2NMT1SIRT6SIRT1GLO1
SCHEMBL29388582 0.86 SIRT6 (0.44) NMT2NMT1SIRT6SIRT1GLO1
SCHEMBL30537468 0.85 ERAP2 (0.45) NMT2NMT1SIRT6SIRT1GLO1
SCHEMBL29569500 0.85 PTGS1 (0.43) NMT2NMT1SIRT6SIRT1GLO1
SCHEMBL29569342 0.85 PTGS1 (0.43) NMT2NMT1SIRT6SIRT1GLO1
SCHEMBL29569082 0.85 PTGS1 (0.43) NMT2NMT1SIRT6SIRT1GLO1
SCHEMBL29871873 0.84 SIRT6 (0.58) NMT2NMT1SIRT6SIRT1GLO1
SCHEMBL31099442 0.84 SIRT6 (0.47) NMT2NMT1SIRT6SIRT1GLO1
SCHEMBL29531200 0.84 SIRT6 (0.47) NMT2NMT1SIRT6SIRT1GLO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250333541-A1 ANTIBODY, AND DRUG CONJUGATE AND USE THEREOF EVOPOINT BIOSCIENCES CO LTD (CN) 2025-10-30 — — US claimed
CN-120189524-A Bispecific antibody-drug conjugate targeting B7H3 and EGFR and application thereof 信达生物制药(苏州)有限公司 2025-06-24 — — CN claimed
CN-119564878-A Bioactive substance conjugate, preparation method and application thereof 苏州宜联生物医药有限公司 2025-03-07 — — CN claimed
CN-119504997-A Bioactive substance conjugate, preparation method and application thereof 苏州宜联生物医药有限公司 2025-02-25 — — CN claimed
EP-4484446-A1 ANTIBODY, AND DRUG CONJUGATE AND USE THEREOF Evopoint Biosciences Co., Ltd. (CN) 2025-01-01 — — EP claimed
US-20240409628-A1 ANTIBODY, ANTIBODY-DRUG CONJUGATE THEREOF AND USE THEREOF Evopoint Biosciences Co., Ltd. (CN) 2024-12-12 — — US claimed
EP-4410372-A1 ANTIBODY, ANTIBODY-DRUG CONJUGATE THEREOF AND USE THEREOF Evopoint Biosciences Co., Ltd. (CN) 2024-08-07 — — EP claimed
WO-2024153185-A1 ANTIBODY-DRUG CONJUGATE CONTAINING BCL-2 FAMILY PROTEOLYSIS AGENT, PREPARATION METHOD THEREFOR, AND USE THEREOF 苏州宜联生物医药有限公司 2024-07-25 — — WO claimed
US-20240108745-A1 BIOACTIVE SUBSTANCE CONJUGATE, PREPARATION METHOD THEREFOR AND USE THEREOF MEDILINK THERAPEUTICS (SUZHOU) CO., LTD. (CN) 2024-04-04 — — US claimed
US-20230357763-A1 Morpholinos with Increased Delivery Efficiency MORPHOLINO THERAPEUTICS LLC 2023-11-09 — — US claimed
EP-4257154-A1 BIOACTIVE SUBSTANCE CONJUGATE, PREPARATION METHOD THEREFOR AND USE THEREOF Medilink Therapeutics (Suzhou) Co., Ltd. (CN) 2023-10-11 — — EP claimed
WO-2023160651-A1 ANTIBODY, AND DRUG CONJUGATE AND USE THEREOF 苏州信诺维医药科技股份有限公司 2023-08-31 — — WO claimed
WO-2023046202-A1 ANTIBODY, ANTIBODY-DRUG CONJUGATE THEREOF AND USE THEREOF 苏州信诺维医药科技股份有限公司 2023-03-30 — — WO claimed
WO-2022170971-A1 BIOACTIVE SUBSTANCE CONJUGATE, PREPARATION METHOD THEREFOR AND USE THEREOF 苏州宜联生物医药有限公司 2022-08-18 — — WO claimed
EP-4748843-A2 ANTIBODY-DRUG CONJUGATE, AND PREPARATION METHOD THEREFOR AND USE THEREOF Medilink Therapeutics (Suzhou) Co., Ltd. (CN) 2026-05-27 — — EP disclosed
EP-4653017-A1 ANTIBODY-DRUG CONJUGATE AND USE THEREOF Tyligand Bioscience (Shanghai) Limited (CN) 2025-11-26 — — EP disclosed
US-20250333541-A1 ANTIBODY, AND DRUG CONJUGATE AND USE THEREOF EVOPOINT BIOSCIENCES CO LTD (CN) 2025-10-30 — — US disclosed
CN-115279417-A Bioactive substance conjugate and preparation method and application thereof 苏州宜联生物医药有限公司 2022-11-01 — — CN disclosed
WO-2022170971-A1 BIOACTIVE SUBSTANCE CONJUGATE, PREPARATION METHOD THEREFOR AND USE THEREOF 苏州宜联生物医药有限公司 2022-08-18 — — WO disclosed
US-20220193069-A1 CAMPTOTHECIN PEPTIDE CONJUGATES SEAGEN INC (US) 2022-06-23 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250333541-A1 ANTIBODY, AND DRUG CONJUGATE AND USE THEREOF TNFRSF9, F13B, FCGR1A NMT2 760/4885NMT1 807/4885SIRT6 1555/4885
US-20240108745-A1 BIOACTIVE SUBSTANCE CONJUGATE, PREPARATION METHOD THEREFOR AND USE THEREOF CTSL, VIP, FURIN NMT2 305/4885NMT1 451/4885SIRT6 2481/4885
US-20240409628-A1 ANTIBODY, ANTIBODY-DRUG CONJUGATE THEREOF AND USE THEREOF EPCAM, CNTN1, STX18 NMT2 949/4885NMT1 1445/4885SIRT6 3754/4885
US-20220193069-A1 CAMPTOTHECIN PEPTIDE CONJUGATES VIP, DCLRE1A, UACA NMT2 104/4885NMT1 94/4885SIRT6 2650/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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