Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 14/20 | 0.98 |
| ▸ | BCHE | P06276 | 5/20 | 0.98 |
| ▸ | POLB | P06746 | 5/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | PKM | P14618 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | SRC | P12931 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20380843 | 1.00 | ACHE (0.98) | ACHEBCHEPOLBKDM4EPKM | |
| SCHEMBL16183136 | 0.87 | ACHE (0.76) | ACHEBCHEPOLBKDM4EPKM | |
| SCHEMBL3443606 | 0.80 | KDM4E (0.68) | ACHEBCHEPOLBKDM4EPKM | |
| SCHEMBL29415213 | 0.80 | KDM4E (0.68) | ACHEBCHEPOLBKDM4EPKM | |
| SCHEMBL85408 | 0.80 | KDM4E (0.68) | ACHEBCHEPOLBKDM4EPKM | |
| SCHEMBL29357702 | 0.80 | KDM4E (0.68) | ACHEBCHEPOLBKDM4EPKM | |
| SCHEMBL10013256 | 0.79 | KDM4E (0.67) | ACHEBCHEPOLBKDM4EPKM | |
| SCHEMBL20380420 | 0.78 | BCHE (0.62) | ACHEBCHEPOLBKDM4EPKM | |
| SCHEMBL16183139 | 0.78 | BCHE (0.62) | ACHEBCHEPOLBKDM4EPKM | |
| SCHEMBL133177 | 0.77 | KDM4E (0.65) | ACHEBCHEPOLBKDM4EPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250326850-A1 | TREATMENT OF LUPUS | ASTRAZENECA AB (SE) | 2025-10-23 | — | — | US | disclosed |
| EP-4603508-A2 | ANTI-FRIZZLED ANTIBODIES AND METHODS OF USE | Surrozen Operating, Inc. (US) | 2025-08-20 | — | — | EP | disclosed |
| US-12241090-B2 | Methods and systems for converting precursor cells into gastric tissues through directed differentiation | CHILDREN'S HOSPITAL MEDICAL CENTER (US) | 2025-03-04 | — | — | US | disclosed |
| CN-119013289-A | Modified IL-18 polypeptides | 明峰治疗股份公司 | 2024-11-22 | — | — | CN | disclosed |
| US-20240368287-A1 | ANTI-FRIZZLED ANTIBODIES AND METHODS OF USE | Surrozen Operating, Inc. | 2024-11-07 | — | — | US | disclosed |
| US-12006368-B2 | Anti-frizzled antibodies and methods of use | Surrozen Operating, Inc. (US) | 2024-06-11 | — | — | US | disclosed |
| EP-4377349-A1 | TREATMENT OF LUPUS | Astrazeneca AB (SE) | 2024-06-05 | — | — | EP | disclosed |
| US-20240141055-A1 | Human Anti-CD27 Antibodies | JANSSEN BIOTECH INC (US) | 2024-05-02 | — | — | US | disclosed |
| CN-117946267-A | Anti-frizzled antibodies and methods of use | 瑟罗泽恩奥普瑞汀公司 | 2024-04-30 | — | — | CN | disclosed |
| CN-111655729-B | Anti-Frizzled Antibodies and Methods of Use | 瑟罗泽恩奥普瑞汀公司 | 2023-10-20 | — | — | CN | disclosed |
| US-11732050-B2 | Neutralizing human anti-CD27 antibodies | JANSSEN BIOTECH, INC. (US) | 2023-08-22 | — | — | US | disclosed |
| WO-2023006700-A1 | TREATMENT OF LUPUS | ASTRAZENECA AB (SE) | 2023-02-02 | — | — | WO | disclosed |
| WO-2023277763-A1 | METHOD OF PREPARING DNA FROM FORMALIN-FIXED-PARAFFIN-EMBEDDED (FFPE) TISSUE SAMPLES | CHEN XINGQI (SE) | 2023-01-05 | — | — | WO | disclosed |
| US-20220056420-A1 | METHODS AND SYSTEMS FOR CONVERTING PRECURSOR CELLS INTO GASTRIC TISSUES THROUGH DIRECTED DIFFERENTIATION | CHILDREN'S HOSPITAL MEDICAL CENTER | 2022-02-24 | — | — | US | disclosed |