Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 6/20 | 0.76 |
| ▸ | BCHE | P06276 | 4/20 | 0.76 |
| ▸ | POLB | P06746 | 5/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | SRC | P12931 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 5/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | APP | P05067 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29389253 | 0.87 | ACHE (0.98) | ACHEBCHEPOLBKDM4EHTT | |
| SCHEMBL20380843 | 0.87 | ACHE (0.98) | ACHEBCHEPOLBKDM4EHTT | |
| SCHEMBL85408 | 0.75 | KDM4E (0.68) | ACHEBCHEPOLBKDM4EHTT | |
| SCHEMBL3443606 | 0.75 | KDM4E (0.68) | ACHEBCHEPOLBKDM4EHTT | |
| SCHEMBL29357702 | 0.75 | KDM4E (0.68) | ACHEBCHEPOLBKDM4EHTT | |
| SCHEMBL29415213 | 0.75 | KDM4E (0.68) | ACHEBCHEPOLBKDM4EHTT | |
| SCHEMBL4849333 | 0.75 | KDM4E (0.67) | POLBKDM4EHTTPKMLMNA | |
| SCHEMBL10013256 | 0.74 | KDM4E (0.67) | ACHEBCHEPOLBKDM4EHTT | |
| SCHEMBL133177 | 0.72 | KDM4E (0.65) | ACHEBCHEPOLBKDM4EHTT | |
| SCHEMBL133176 | 0.72 | KDM4E (0.65) | ACHEBCHEPOLBKDM4EHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10024863-B2 | Methods for dye selection for protein melt temperature determinations | Life Technologies Corporation (US) | 2018-07-17 | — | — | US | disclosed |
| US-20140315190-A1 | METHODS FOR DYE SELECTION FOR PROTEIN MELT TEMPERATURE DETERMINATIONS | Life Technologies Corporation | 2014-10-23 | — | — | US | disclosed |