Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 3/20 | 0.62 |
| ▸ | ACHE | P22303 | 3/20 | 0.62 |
| ▸ | POLB | P06746 | 5/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | HTT | P42858 | 3/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 7/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.40 |
| ▸ | SRC | P12931 | 2/20 | 0.39 |
| ▸ | APP | P05067 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.38 |
| ▸ | LMNA | P02545 | 5/20 | 0.38 |
| ▸ | HPGD | P15428 | 5/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.38 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20380420 | 0.91 | BCHE (0.62) | BCHEACHEPOLBKDM4EHTT | |
| SCHEMBL16091912 | 0.83 | KDM4E (0.48) | BCHEACHEPOLBKDM4EHTT | |
| SCHEMBL16183130 | 0.82 | POLB (0.49) | BCHEACHEPOLBKDM4EHTT | |
| SCHEMBL16091909 | 0.81 | APP (0.54) | BCHEACHEPOLBKDM4EHTT | |
| SCHEMBL29804003 | 0.81 | BCHE (0.55) | BCHEACHEPOLBKDM4EHTT | |
| SCHEMBL18105118 | 0.79 | KMT2A (0.45) | ACHEPOLBKDM4EHTTPKM | |
| SCHEMBL29389253 | 0.78 | ACHE (0.98) | BCHEACHEPOLBKDM4EHTT | |
| SCHEMBL20380843 | 0.78 | ACHE (0.98) | BCHEACHEPOLBKDM4EHTT | |
| SCHEMBL16183115 | 0.74 | INSR (0.49) | BCHEACHEPOLBHTTPKM | |
| SCHEMBL1105748 | 0.74 | LMNA (0.43) | BCHEACHEPOLBKDM4EHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140315190-A1 | METHODS FOR DYE SELECTION FOR PROTEIN MELT TEMPERATURE DETERMINATIONS | Life Technologies Corporation | 2014-10-23 | — | — | US | disclosed |