SCHEMBL29389812

SCHEMBL29389812

N=C(N)NCCC[C@H](NC(=O)[C@@H](N)Cc1c[nH]c2ccccc12)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(N)=O

nearest known ligand 0.56

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ NPY1R P25929 3/20 0.56
▸ NPY2R P49146 3/20 0.56
▸ NPY4R P50391 3/20 0.56
▸ KISS1R Q969F8 13/20 0.55
▸ MC4R P32245 2/20 0.54
▸ ECE1 P42892 1/20 0.53
▸ OPRM1 P35372 1/20 0.53
▸ OPRD1 P41143 1/20 0.53
▸ OPRK1 P41145 1/20 0.53
▸ OPRL1 P41146 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31193767 0.96 NPY4R (0.60) NPY1RNPY2RNPY4RKISS1RMC4R
SCHEMBL31193750 0.94 NPY4R (0.58) NPY1RNPY2RNPY4RKISS1RMC4R
SCHEMBL30635329 0.94 ECE1 (0.52) NPY1RNPY2RNPY4RKISS1RMC4R
SCHEMBL17827357 0.94 ECE1 (0.52) NPY1RNPY2RNPY4RKISS1RMC4R
SCHEMBL28175487 0.94 ECE1 (0.52) NPY1RNPY2RNPY4RKISS1RMC4R
SCHEMBL29641173 0.94 GHSR (0.60) —
SCHEMBL29483770 0.94 GHSR (0.60) —
SCHEMBL29483769 0.94 GHSR (0.60) —
SCHEMBL22117388 0.94 KISS1R (0.61) NPY1RNPY2RNPY4RKISS1RMC4R
SCHEMBL22117389 0.94 KISS1R (0.61) NPY1RNPY2RNPY4RKISS1RMC4R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250205164-A1 FPR2 AGONIST CONTAINING OUTER MEMBRANE VESICLES DERIVED FROM LACTIC ACID BACTERIUM ASAHI GROUP HOLDINGS, LTD. (JP) 2025-06-26 — — US disclosed
EP-4548780-A1 FPR2 AGONIST CONTAINING OUTER MEMBRANE VESICLES DERIVED FROM LACTIC ACID BACTERIUM Asahi Group Holdings, Ltd. (JP) 2025-05-07 — — EP disclosed
US-12065485-B2 Treatment of staphylococcal disorders THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) 2024-08-20 — — US disclosed
WO-2023229034-A1 FPR2 AGONIST CONTAINING OUTER MEMBRANE VESICLES DERIVED FROM LACTIC ACID BACTERIUM アサヒグループホールディングス株式会社 2023-11-30 — — WO disclosed
US-20220048979-A1 TREATMENT OF STAPHYLOCOCCAL DISORDERS THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERAN AFFAIRS 2022-02-17 — — US disclosed
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