SCHEMBL29390532

SCHEMBL29390532

CN(C)c1ncnc2c1ncn2[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ADORA2A P29274 2/20 0.69
▸ ADORA2B P29275 2/20 0.69
▸ SLC29A1 Q99808 2/20 0.69
▸ DPP4 P27487 1/20 0.69
▸ MEN1 O00255 1/20 0.69
▸ SLC28A1 O00337 1/20 0.69
▸ MAP3K7 O43318 1/20 0.69
▸ SLC28A2 O43868 1/20 0.69
▸ GAPDH P04406 1/20 0.69
▸ ADORA3 P0DMS8 1/20 0.69
▸ MAPK1 P28482 1/20 0.69
▸ ADORA1 P30542 1/20 0.69
▸ STAT6 P42226 1/20 0.69
▸ PI4KA P42356 1/20 0.69
▸ KMT2A Q03164 1/20 0.69
▸ SMN1; SMN2 Q16637 1/20 0.69
▸ PI4K2B Q8TCG2 1/20 0.69
▸ DOT1L Q8TEK3 1/20 0.69
▸ PI4K2A Q9BTU6 1/20 0.69
▸ SLC28A3 Q9HAS3 1/20 0.69

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18503540 1.00 ADORA2A (0.69) ADORA2AADORA2BSLC29A1DPP4MEN1
SCHEMBL27419960 1.00 ADORA2A (0.69) ADORA2AADORA2BSLC29A1DPP4MEN1
SCHEMBL15623876 1.00 ADORA2A (0.69) ADORA2AADORA2BSLC29A1DPP4MEN1
SCHEMBL3150637 1.00 ADORA2A (0.69) ADORA2AADORA2BSLC29A1DPP4MEN1
SCHEMBL157531 1.00 ADORA2A (0.69) ADORA2AADORA2BSLC29A1DPP4MEN1
SCHEMBL29435131 1.00 ADORA2A (0.69) ADORA2AADORA2BSLC29A1DPP4MEN1
SCHEMBL18486352 1.00 ADORA2A (0.69) ADORA2AADORA2BSLC29A1DPP4MEN1
SCHEMBL1996593 1.00 ADORA2A (0.69) ADORA2AADORA2BSLC29A1DPP4MEN1
SCHEMBL20579764 1.00 ADORA2A (0.69) ADORA2AADORA2BSLC29A1DPP4MEN1
SCHEMBL157530 1.00 ADORA2A (0.69) ADORA2AADORA2BSLC29A1DPP4MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 307 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260139030-A1 CHIMERIC PROTEINS FOR TREATING CUTANEOUS INFLAMMATION SHATTUCK LABS INC (US) 2026-05-21 — — US claimed
WO-2025109169-A1 IMPROVED METHOD FOR IDENTIFICATION OF NUCLEOTIDE MODIFICATIONS OXFORD UNIVERSITY INNOVATION LIMITED (GB) 2025-05-30 — — WO claimed
CN-117866948-B Negative selection method and system for purifying circular nucleic acid 上海环码生物医药有限公司 2024-12-13 — — CN claimed
WO-2024086659-A2 COMPOSITION AND METHODS FOR DETECTING ADENINE MODIFICATIONS THE UNIVERSITY OF CHICAGO (US) 2024-04-25 — — WO claimed
EP-4347841-A1 CONSTRUCTS AND METHODS FOR PREPARING CIRCULAR RNAS AND USE THEREOF Shanghai Circode Biomed Co., Ltd. (CN) 2024-04-10 — — EP claimed
US-20230099822-A1 MR1 LIGANDS AND PHARMACEUTICAL COMPOSITIONS FOR IMMUNOMODULATION UNIVERSITÄT BASEL (CH) 2023-03-30 — — US claimed
WO-2023023055-A1 COMPOSITIONS AND METHODS FOR OPTIMIZING TROPISM OF DELIVERY SYSTEMS FOR RNA RENAGADE THERAPEUTICS MANAGEMENT INC. (US) 2023-02-23 — — WO claimed
WO-2022247943-A1 CONSTRUCTS AND METHODS FOR PREPARING CIRCULAR RNAS AND USE THEREOF Shanghai Circode Biomed Co., Ltd. (CN) 2022-12-01 — — WO claimed
EP-4090969-A1 MR1 LIGANDS AND PHARMACEUTICAL COMPOSITIONS FOR IMMUNOMODULATION Universität Basel (CH) 2022-11-23 — — EP claimed
CN-114929244-A Mannose-based mRNA targeted delivery system and application thereof 深圳市瑞吉生物科技有限公司 2022-08-19 — — CN claimed
CN-114076805-B Method for enriching methylated adenosine in urine and application thereof 浙江大学 2022-07-26 — — CN claimed
WO-2022115822-A2 METHODS FOR FULL-LENGTH REVERSE TRANSCRIPTION PCR OF LONG RNAS CONTAINING MODIFIED RIBONUCLEOSIDES USING A THERMOSTABLE REVERSE TRANSCRIPTASE NORTHWESTERN UNIVERSITY (US) 2022-06-02 — — WO claimed
EP-4747380-A1 MODULATING EXPRESSION OF ALAS1 (5'-AMINOLEVULINATE SYNTHASE 1) GENE CRISPR Therapeutics AG (CH) 2026-05-27 — — EP disclosed
US-12636304-B2 — — 2026-05-26 — — US disclosed
WO-2026107055-A1 HEPATITIS B VIRUS VACCINE AND METHODS OF USE THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 2026-05-21 — — WO disclosed
WO-2026105091-A1 COMPOSITIONS AND METHODS TO MODULATE TRANSPOSABLE ELEMENTS GOVERNING CELL-STATE TRANSITIONS HAYA THERAPEUTICS SA (CH) 2026-05-21 — — WO disclosed
US-11273209-B2 Methods and compositions for RNA-guided treatment of HIV infection Temple University—Of the Commonwealth System of Higher Education (US) 2022-03-15 — — US disclosed
EP-3958893-A1 MRNA FORMULATION eTheRNA Immunotherapies NV (BE) 2022-03-02 — — EP disclosed
CN-114096272-A mRNA formulations 伊泽阿恩埃免疫疗法股份有限公司 2022-02-25 — — CN disclosed
EP-3942042-A1 METHODS AND COMPOSITIONS FOR EDITING NUCLEOTIDE SEQUENCES The Broad Institute, Inc. (US) 2022-01-26 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12636304-B2 — RNMT, RNGTT, NSUN2 ADORA2A 494/4885ADORA2B 758/4885SLC29A1 390/4885
US-20230099822-A1 MR1 LIGANDS AND PHARMACEUTICAL COMPOSITIONS FOR IMMUNOMODULATION MRGPRX1, MRGPRX2, CD47 ADORA2A 82/4885ADORA2B 133/4885SLC29A1 650/4885
US-20260139030-A1 CHIMERIC PROTEINS FOR TREATING CUTANEOUS INFLAMMATION TNFRSF9, CD40, TNFSF11 ADORA2A 1523/4885ADORA2B 1846/4885SLC29A1 3820/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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