Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 1/20 | 0.44 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.44 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.43 |
| ▸ | CPB2 | Q96IY4 | 8/20 | 0.43 |
| ▸ | FURIN | P09958 | 7/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.39 |
| ▸ | NMT2 | O60551 | 1/20 | 0.39 |
| ▸ | NMT1 | P30419 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29392650 | 0.99 | FOLH1 (0.45) | FOLH1SLC6A5SLC15A2CPB2FURIN | |
| SCHEMBL29389004 | 0.90 | SLC15A2 (0.51) | FOLH1SLC6A5SLC15A2CPB2FURIN | |
| SCHEMBL31319761 | 0.88 | C3AR1 (0.41) | SLC15A2CPB2FURINPRSS1 | |
| SCHEMBL24191073 | 0.87 | C3AR1 (0.42) | SLC15A2CPB2FURINPRSS1 | |
| SCHEMBL29893406 | 0.87 | FOLH1 (0.53) | FOLH1SLC6A5SLC15A2CPB2 | |
| SCHEMBL8821211 | 0.87 | FOLH1 (0.53) | FOLH1SLC6A5SLC15A2CPB2 | |
| SCHEMBL8821210 | 0.87 | FOLH1 (0.53) | FOLH1SLC6A5SLC15A2CPB2 | |
| SCHEMBL15756737 | 0.85 | FOLH1 (0.54) | FOLH1SLC6A5SLC15A2CPB2 | |
| SCHEMBL4299646 | 0.85 | FOLH1 (0.54) | FOLH1SLC6A5SLC15A2CPB2 | |
| SCHEMBL6850341 | 0.85 | FURIN (0.40) | FURINPRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022199237-A1 | MODIFIED AMINO ACIDS AND APPLICATION THEREOF IN ADC | 联宁（苏州）生物制药有限公司 | 2022-09-29 | — | — | WO | claimed |
| CN-114106088-A | Bromomethylpyrazine-based drug conjugates and ADCs | 联宁（苏州）生物制药有限公司 | 2022-03-01 | — | — | CN | claimed |
| CN-113816969-B | Eptification control compound, antibody drug conjugate thereof and application thereof | 联宁（苏州）生物制药有限公司 | 2024-01-16 | — | — | CN | disclosed |
| WO-2022199237-A1 | MODIFIED AMINO ACIDS AND APPLICATION THEREOF IN ADC | 联宁（苏州）生物制药有限公司 | 2022-09-29 | — | — | WO | disclosed |
| CN-114106088-A | Bromomethylpyrazine-based drug conjugates and ADCs | 联宁（苏州）生物制药有限公司 | 2022-03-01 | — | — | CN | disclosed |