SCHEMBL4299646

SCHEMBL4299646

NCCCC[C@H](NC(=O)CNC(=O)CN)C(=O)O

nearest known ligand 0.54

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 2/20 0.54
SLC6A5 Q9Y345 1/20 0.52
SLC15A2 Q16348 1/20 0.48
CPB2 Q96IY4 7/20 0.44
GNPAT O15228 1/20 0.43
F2 P00734 1/20 0.42
GSR P00390 1/20 0.42
RNPEP Q9H4A4 1/20 0.41
CA1 P00915 1/20 0.40
CA2 P00918 1/20 0.40
MMP2 P08253 1/20 0.39
MMP9 P14780 1/20 0.39
NOD1 Q9Y239 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15756737 1.00 FOLH1 (0.54) FOLH1SLC6A5SLC15A2CPB2GNPAT
SCHEMBL29893406 0.98 FOLH1 (0.53) FOLH1SLC6A5SLC15A2CPB2GNPAT
SCHEMBL8821210 0.98 FOLH1 (0.53) FOLH1SLC6A5SLC15A2CPB2GNPAT
SCHEMBL8821211 0.98 FOLH1 (0.53) FOLH1SLC6A5SLC15A2CPB2GNPAT
SCHEMBL30932293 0.94 FOLH1 (0.49) FOLH1SLC6A5SLC15A2CPB2GNPAT
SCHEMBL27204494 0.93 FOLH1 (0.48) FOLH1SLC6A5SLC15A2CPB2GNPAT
SCHEMBL27164811 0.93 FOLH1 (0.48) FOLH1SLC6A5SLC15A2CPB2GNPAT
Glycylglycylglycine SCHEMBL2567025 0.91 FOLH1 (0.52) FOLH1SLC6A5SLC15A2CPB2GNPAT
SCHEMBL32672545 0.90 NMT1 (0.51) FOLH1SLC6A5SLC15A2
SCHEMBL7797130 0.89 SLC15A2 (0.49) FOLH1SLC6A5SLC15A2CPB2F2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025031383-A1 BIFUNCTIONAL LINKER COMPOUND, ANTIBODY DRUG CONJUGATE, PREPARATION METHOD FOR ANTIBODY DRUG CONJUGATE, AND USE OF ANTIBODY DRUG CONJUGATE 杭州爱科瑞思生物医药有限公司 2025-02-13 WO claimed
CN-115925788-A Anglerfish swim bladder antioxidant peptide for treating non-alcoholic fatty liver disease and preparation method and application thereof 浙江海洋大学 2023-04-07 CN claimed
EP-3818072-A1 MEANS AND METHODS FOR SITE-SPECIFIC PROTEIN MODIFICATION USING TRANSPEPTIDASES Technische Universität München (DE) 2021-05-12 EP claimed
WO-2020007899-A1 MEANS AND METHODS FOR SITE-SPECIFIC PROTEIN MODIFICATION USING TRANSPEPTIDASES Technische Universität München (DE) 2020-01-09 WO claimed
US-20150291659-A1 SOLOMONAMIDE ANALOGUE COMPOUNDS, PHARMACEUTICALS CONTAINING SOLOMONAMIDE ANALOGUE COMPOUNDS, AND PROCESSES FOR THE PREPARATION THEREOF COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2015-10-15 US claimed
EP-2925771-A1 A PROCESS FOR THE PREPARATION OF SOLOMONAMIDE ANALOGUES Council of Scientific & Industrial Research (IN) 2015-10-07 EP claimed
WO-2014083578-A1 A PROCESS FOR THE PREPARATION OF SOLOMONAMIDE ANALOGUES COUNCIL OF SCIENTIFIC & INDUSTRIAL RESERACH AN INDIAN REGISTERED BODY INCORPORATED UNDER THE REGN. OF SOC. ACT (ACT XXI OF 1860) (IN) 2014-06-05 WO claimed
EP-4696700-A1 LONG-ACTING K-OPIOID RECEPTOR AGONIST Chengdu Aoda Biotechnology Co., Ltd (CN) 2026-02-18 EP disclosed
US-20250099632-A1 CLEAVABLE RADIOLIGANDS FOR TARGETING CELL SURFACE RECEPTORS AND USES THEREOF FULL-LIFE TECHNOLOGIES UK LIMITED (GB) 2025-03-27 US disclosed
US-20250074942-A1 COMPOSITIONS AND METHODS FOR COVALENT PEPTIDE-BASED MODULATORS OF HLA-E CALICO LIFE SCIENCES LLC (US) 2025-03-06 US disclosed
WO-2025031383-A1 BIFUNCTIONAL LINKER COMPOUND, ANTIBODY DRUG CONJUGATE, PREPARATION METHOD FOR ANTIBODY DRUG CONJUGATE, AND USE OF ANTIBODY DRUG CONJUGATE 杭州爱科瑞思生物医药有限公司 2025-02-13 WO disclosed
US-12214059-B2 Cleavable radioligands for targeting cell surface receptors and uses thereof FULL-LIFE TECHNOLOGIES HK LIMITED (CN) 2025-02-04 US disclosed
US-12180299-B2 Multispecific antibody analogs comprising a common light chain, and methods of their preparation and use ADIMAB, LLC (US) 2024-12-31 US disclosed
WO-2020007899-A1 MEANS AND METHODS FOR SITE-SPECIFIC PROTEIN MODIFICATION USING TRANSPEPTIDASES Technische Universität München (DE) 2020-01-09 WO disclosed
US-9868781-B2 Antibodies for ubiquitinated proteins CORNELL UNIVERSITY (US) 2018-01-16 US disclosed
US-9751911-B2 Solomonamide analogue compounds, pharmaceuticals containing solomonamide analogue compounds, and processes for the preparation thereof COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2017-09-05 US disclosed
US-20150291659-A1 SOLOMONAMIDE ANALOGUE COMPOUNDS, PHARMACEUTICALS CONTAINING SOLOMONAMIDE ANALOGUE COMPOUNDS, AND PROCESSES FOR THE PREPARATION THEREOF COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2015-10-15 US disclosed
EP-2925771-A1 A PROCESS FOR THE PREPARATION OF SOLOMONAMIDE ANALOGUES Council of Scientific & Industrial Research (IN) 2015-10-07 EP disclosed
WO-2014083578-A1 A PROCESS FOR THE PREPARATION OF SOLOMONAMIDE ANALOGUES COUNCIL OF SCIENTIFIC & INDUSTRIAL RESERACH AN INDIAN REGISTERED BODY INCORPORATED UNDER THE REGN. OF SOC. ACT (ACT XXI OF 1860) (IN) 2014-06-05 WO disclosed
US-20090317409-A1 Antibodies for ubiquitinated proteins CORNELL RESEARCH FOUNDATION, INC. (US) 2009-12-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090317409-A1 Antibodies for ubiquitinated proteins UBQLN1, STUB1, UBAP2 FOLH1 1865/4885SLC6A5 4646/4885SLC15A2 4551/4885
US-12214059-B2 Cleavable radioligands for targeting cell surface receptors and uses thereof ASGR1, GNRHR, SCTR FOLH1 22/4885SLC6A5 1181/4885SLC15A2 983/4885
US-20250099632-A1 CLEAVABLE RADIOLIGANDS FOR TARGETING CELL SURFACE RECEPTORS AND USES THEREOF ASGR1, GNRHR, SCTR FOLH1 22/4885SLC6A5 1181/4885SLC15A2 983/4885
US-20250074942-A1 COMPOSITIONS AND METHODS FOR COVALENT PEPTIDE-BASED MODULATORS OF HLA-E MICA, CD74, HLA-DRB1 FOLH1 2388/4885SLC6A5 4187/4885SLC15A2 1915/4885
US-20150291659-A1 SOLOMONAMIDE ANALOGUE COMPOUNDS, PHARMACEUTICALS CONTAINING SOLOMONAMIDE ANALOGUE COMPOUNDS, AND PROCESSES FOR THE PREPARATION THEREOF CNR2, SRM, CNR1 FOLH1 2756/4885SLC6A5 2870/4885SLC15A2 3402/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.