SCHEMBL29893406

SCHEMBL29893406

NCCCC[C@H](NC(=O)CNC(=O)CNC(=O)CNC(=O)CN)C(=O)O

nearest known ligand 0.53

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 2/20 0.53
SLC6A5 Q9Y345 1/20 0.51
SLC15A2 Q16348 1/20 0.47
CPB2 Q96IY4 7/20 0.43
GNPAT O15228 1/20 0.42
F2 P00734 1/20 0.41
GSR P00390 1/20 0.41
CA1 P00915 1/20 0.40
CA2 P00918 1/20 0.40
RNPEP Q9H4A4 1/20 0.40
MMP2 P08253 1/20 0.38
MMP9 P14780 1/20 0.38
NOD1 Q9Y239 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8821211 1.00 FOLH1 (0.53) FOLH1SLC6A5SLC15A2CPB2GNPAT
SCHEMBL8821210 1.00 FOLH1 (0.53) FOLH1SLC6A5SLC15A2CPB2GNPAT
SCHEMBL4299646 0.98 FOLH1 (0.54) FOLH1SLC6A5SLC15A2CPB2GNPAT
SCHEMBL15756737 0.98 FOLH1 (0.54) FOLH1SLC6A5SLC15A2CPB2GNPAT
SCHEMBL27204494 0.94 FOLH1 (0.48) FOLH1SLC6A5SLC15A2CPB2GNPAT
SCHEMBL27164811 0.94 FOLH1 (0.48) FOLH1SLC6A5SLC15A2CPB2GNPAT
SCHEMBL30932293 0.93 FOLH1 (0.49) FOLH1SLC6A5SLC15A2CPB2GNPAT
Glycylglycylglycine SCHEMBL2567025 0.93 FOLH1 (0.52) FOLH1SLC6A5SLC15A2CPB2GNPAT
SCHEMBL30455335 0.91 NMT1 (0.50) FOLH1SLC6A5SLC15A2
SCHEMBL32672545 0.89 NMT1 (0.51) FOLH1SLC6A5SLC15A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250295821-A1 TARGETED RADIOPHARMACEUTICAL FOR TUMOR AND ITS USE IN THE IMAGING-GUIDED COMBINATION THERAPY OF TARGETED RADIOTHERAPY AND IMMUNOTHERAPY BeijingGiluntidePharmaceuticalCo.,Ltd. (CN) 2025-09-25 US disclosed
US-12357712-B2 Targeted radiopharmaceutical for tumor and its use in the imaging-guided combination therapy of targeted radiotherapy and immunotherapy BEIJING GILUNTIDE PHARMACEUTICAL CO., LTD. (CN) 2025-07-15 US disclosed
US-12180299-B2 Multispecific antibody analogs comprising a common light chain, and methods of their preparation and use ADIMAB, LLC (US) 2024-12-31 US disclosed
US-12181480-B2 Polyspecificity reagents, methods for their preparation and use ADIMAB, LLC (US) 2024-12-31 US disclosed
EP-3280444-B1 METHODS FOR PURIFYING HETERODIMERIC MULTISPECIFIC ANTIBODIES FROM PARENTAL HOMODIMERIC ANTIBODY SPECIES ADIMAB LLC (US) 2024-05-08 EP disclosed
US-20230117927-A1 Targeted Radiopharmaceutical for Tumor and Its Use in the Imaging-guided Combination Therapy of Targeted Radiotherapy and Immunotherapy BEIJING GILUNTIDE PHARMACEUTICAL CO., LTD. (CN) 2023-04-20 US disclosed
US-20230115655-A1 ENGINEERED POLYPEPTIDES HAVING ENHANCED DURATION OF ACTION ASTRAZENECA PHARMACEUTICALS LP 2023-04-13 US disclosed
CN-108472360-B Method for purifying heterodimeric multispecific antibodies from parent homodimeric antibody species 阿迪马布有限责任公司 2023-01-17 CN disclosed
US-11535659-B2 Engineered polypeptides having enhanced duration of action AMRYT PHARMACEUTICALS INC. (US) 2022-12-27 US disclosed
EP-4050026-A1 METHOD OF OBTAINING OR IDENTIFYING ONE OR MORE COMMON LIGHT CHAINS FOR USE IN PREPARING A MULTISPECIFIC ANTIBODY Adimab, LLC (US) 2022-08-31 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250295821-A1 TARGETED RADIOPHARMACEUTICAL FOR TUMOR AND ITS USE IN THE IMAGING-GUIDED COMBINATION THERAPY OF TARGETED RADIOTHERAPY AND IMMUNOTHERAPY CD274, ITGB1, ITGA1 FOLH1 316/4885SLC6A5 4809/4885SLC15A2 4403/4885
US-20230115655-A1 ENGINEERED POLYPEPTIDES HAVING ENHANCED DURATION OF ACTION IAPP, HDGF, FABP1 FOLH1 211/4885SLC6A5 4657/4885SLC15A2 1885/4885
US-11535659-B2 Engineered polypeptides having enhanced duration of action IAPP, HDGF, FABP1 FOLH1 211/4885SLC6A5 4657/4885SLC15A2 1885/4885
US-12357712-B2 Targeted radiopharmaceutical for tumor and its use in the imaging-guided combination therapy of targeted radiotherapy and immunotherapy CD274, ITGB1, ITGA1 FOLH1 316/4885SLC6A5 4809/4885SLC15A2 4403/4885
US-20230117927-A1 Targeted Radiopharmaceutical for Tumor and Its Use in the Imaging-guided Combination Therapy of Targeted Radiotherapy and Immunotherapy CD274, ITGB1, ITGA1 FOLH1 316/4885SLC6A5 4809/4885SLC15A2 4403/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.