Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 6/20 | 1.00 |
| ▸ | ROCK1 | Q13464 | 5/20 | 1.00 |
| ▸ | PRKACA | P17612 | 3/20 | 1.00 |
| ▸ | PRKACG | P22612 | 3/20 | 1.00 |
| ▸ | PRKACB | P22694 | 3/20 | 1.00 |
| ▸ | CCL2 | P13500 | 2/20 | 1.00 |
| ▸ | CLK1 | P49759 | 2/20 | 1.00 |
| ▸ | KCNH2 | Q12809 | 2/20 | 1.00 |
| ▸ | PKN1 | Q16512 | 2/20 | 1.00 |
| ▸ | PKN2 | Q16513 | 2/20 | 1.00 |
| ▸ | PRKD2 | Q9BZL6 | 2/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 1.00 |
| ▸ | ULK1 | O75385 | 1/20 | 1.00 |
| ▸ | PARP1 | P09874 | 1/20 | 1.00 |
| ▸ | HPGD | P15428 | 1/20 | 1.00 |
| ▸ | ACAD10 | Q6JQN1 | 1/20 | 1.00 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.97 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.73 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.73 |
| ▸ | MYLK | Q15746 | 3/20 | 0.73 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydroxyfasudil SCHEMBL123699 | 1.00 | ROCK2 (1.00) | ROCK2ROCK1PRKACAPRKACGPRKACB | |
| Hydroxyfasudil SCHEMBL16499912 | 0.99 | ROCK2 (1.00) | ROCK2ROCK1PRKACAPRKACGPRKACB | |
| SCHEMBL29351112 | 0.84 | ROCK1 (1.00) | ROCK2ROCK1PRKACAPRKACGPRKACB | |
| SCHEMBL1271163 | 0.84 | ROCK1 (1.00) | ROCK2ROCK1PRKACAPRKACGPRKACB | |
| Hydrochloric Acid SCHEMBL29651499 | 0.83 | LMNA (1.00) | ROCK2ROCK1PRKACAPRKACGPRKACB | |
| Hydrochloric Acid SCHEMBL30237215 | 0.83 | LMNA (1.00) | ROCK2ROCK1PRKACAPRKACGPRKACB | |
| Hydrochloric Acid SCHEMBL3691324 | 0.83 | LMNA (1.00) | ROCK2ROCK1PRKACAPRKACGPRKACB | |
| SCHEMBL2869228 | 0.83 | CYP3A4 (1.00) | ROCK2ROCK1PRKACAPRKACGPRKACB | |
| Hydrochloric Acid SCHEMBL1981350 | 0.82 | ROCK1 (0.95) | ROCK2ROCK1PRKACAPRKACGPRKACB | |
| Hydrochloric Acid SCHEMBL1848494 | 0.82 | MAPK1 (1.00) | ROCK2ROCK1PRKACAPRKACGPRKACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 112 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4744663-A2 | SKIN COMPOSITION | Eaderm Co., Ltd. (JP) | 2026-05-20 | — | — | EP | claimed |
| EP-3843845-B1 | INHIBITION OF PROTEIN KINASES TO TREAT FRIEDREICH ATAXIA | UNIV MASSACHUSETTS (US) | 2026-03-11 | — | — | EP | claimed |
| US-20250206845-A1 | PHARMACEUTICAL COMPOSITION INCLUDING RHO-KINASE INHIBITOR FOR PREVENTION OR TREATMENT OF CUTANEOUS FIBROTIC DISORDERS SUCH AS KELOID, ETC. AND USE THEREOF | SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION (KR) | 2025-06-26 | — | — | US | claimed |
| US-20250179437-A1 | LATRUNCULIN A FOR PRODUCING PRIMITIVE STREAK CELLS | UNIVERSITY HEALH NETWORK (CA) | 2025-06-05 | — | — | US | claimed |
| US-20240342175-A1 | Compositions and Methods for Treating Spinal Cord Injury and Synaptic Dysfunction | MITZ HOWARD (US) | 2024-10-17 | — | — | US | claimed |
| US-20240182864-A1 | NOVEL CHEMICAL COMBINATIONS AND METHODS OF USE THEREOF, TOWARDS DIFFERENTIATION OF HUMAN PROGENITOR CELLS INTO FUNCTIONAL BETA CELLS | SALK INSTITUTE FOR BIOLOGICAL STUDIES | 2024-06-06 | — | — | US | claimed |
| CN-118079006-A | Skin composition | 国立大学法人东京医科齿科大学 | 2024-05-28 | — | — | CN | claimed |
| EP-4319877-A1 | COMPOSITIONS AND METHODS FOR TREATING SPINAL CORD INJURY AND SYNAPTIC DYSFUNCTION | Mitz, Howard (US) | 2024-02-14 | — | — | EP | claimed |
| US-20240000935-A1 | ANTIGEN SPECIFIC T CELLS AND METHODS OF MAKING AND USING SAME | GENEIUS BIOTECHNOLOGY, INC. (US) | 2024-01-04 | — | — | US | claimed |
| WO-2023223519-A1 | METHOD FOR DEACTIVATING ACTIVATED STELLATE CELLS | ＩＳＭ株式会社 | 2023-11-23 | — | — | WO | claimed |
| EP-4251177-A2 | ANTIGEN SPECIFIC T CELLS AND METHODS OF MAKING AND USING SAME | Geneius Biotechnology, Inc. (US) | 2023-10-04 | — | — | EP | claimed |
| WO-2023182856-A1 | PHARMACEUTICAL COMPOSITION INCLUDING RHO-KINASE INHIBITOR FOR PREVENTION OR TREATMENT OF CUTANEOUS FIBROTIC DISORDERS SUCH AS KELOID, ETC. AND USE THEREOF | 서울대학교산학협력단 | 2023-09-28 | — | — | WO | claimed |
| US-20220331389-A1 | SKIN COMPOSITION | EADERM CO., LTD. (JP) | 2022-10-20 | — | — | US | claimed |
| WO-2022216537-A1 | COMPOSITIONS AND METHODS FOR TREATING SPINAL CORD INJURY AND SYNAPTIC DYSFUNCTION | MITZ HOWARD (US) | 2022-10-13 | — | — | WO | claimed |
| US-20220323440-A1 | COMPOSITIONS AND METHODS FOR TREATING SPINAL CORD INJURY AND SYNAPTIC DYSFUNCTION | MITZ HOWARD (US) | 2022-10-13 | — | — | US | claimed |
| WO-2022204377-A1 | NOVEL CHEMICAL COMBINATIONS AND METHODS OF USE THEREOF, TOWARDS DIFFERENTIATION OF HUMAN PROGENITOR CELLS INTO FUNCTIONAL β CELLS | SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 2022-09-29 | — | — | WO | claimed |
| WO-2022115641-A2 | ANTIGEN SPECIFIC T CELLS AND METHODS OF MAKING AND USING SAME | GENEIUS BIOTECHNOLOGY, INC. (US) | 2022-06-02 | — | — | WO | claimed |
| EP-3978020-A1 | SKIN COMPOSITION | National University Corporation Tokyo Medical and Dental University (JP) | 2022-04-06 | — | — | EP | claimed |
| EP-4744663-A2 | SKIN COMPOSITION | Eaderm Co., Ltd. (JP) | 2026-05-20 | — | — | EP | disclosed |
| US-20220049220-A1 | EMBRYONIC ERYTHROBLAST-CONTAINING CELL POPULATION AND METHOD FOR PRODUCING SAME, CELL CULTURE COMPOSITION, AND COMPOUND TEST METHOD | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2022-02-17 | — | — | US | disclosed |