Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK1 | Q13464 | 5/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 5/20 | 1.00 |
| ▸ | CYP2D6 | P10635 | 3/20 | 1.00 |
| ▸ | MYLK | Q15746 | 3/20 | 1.00 |
| ▸ | NFKB1 | P19838 | 3/20 | 1.00 |
| ▸ | CYP1A2 | P05177 | 3/20 | 1.00 |
| ▸ | TSHR | P16473 | 3/20 | 1.00 |
| ▸ | TP53 | P04637 | 2/20 | 1.00 |
| ▸ | CYP2C19 | P33261 | 2/20 | 1.00 |
| ▸ | MTOR | P42345 | 1/20 | 1.00 |
| ▸ | RAB9A | P51151 | 1/20 | 1.00 |
| ▸ | LMNA | P02545 | 3/20 | 0.97 |
| ▸ | GMNN | O75496 | 2/20 | 0.97 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.97 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.74 |
| ▸ | MEN1 | O00255 | 4/20 | 0.74 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.74 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.74 |
| ▸ | ROCK2 | O75116 | 6/20 | 0.73 |
| ▸ | PRKACA | P17612 | 3/20 | 0.73 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1271163 | 1.00 | ROCK1 (1.00) | ROCK1CYP3A4CYP2D6MYLKNFKB1 | |
| Hydrochloric Acid SCHEMBL30237215 | 0.99 | LMNA (1.00) | ROCK1CYP3A4CYP2D6MYLKNFKB1 | |
| Hydrochloric Acid SCHEMBL29651499 | 0.99 | LMNA (1.00) | ROCK1CYP3A4CYP2D6MYLKNFKB1 | |
| Hydrochloric Acid SCHEMBL3691324 | 0.99 | LMNA (1.00) | ROCK1CYP3A4CYP2D6MYLKNFKB1 | |
| Hydrochloric Acid SCHEMBL1981350 | 0.97 | ROCK1 (0.95) | ROCK1CYP3A4CYP2D6MYLKNFKB1 | |
| SCHEMBL2869228 | 0.85 | CYP3A4 (1.00) | ROCK1CYP3A4CYP2D6MYLKNFKB1 | |
| Hydroxyfasudil SCHEMBL123699 | 0.84 | ROCK2 (1.00) | ROCK1CYP3A4CYP2D6MYLKNFKB1 | |
| Hydroxyfasudil SCHEMBL29395466 | 0.84 | ROCK2 (1.00) | ROCK1CYP3A4CYP2D6MYLKNFKB1 | |
| SCHEMBL16613226 | 0.84 | KMT2A (0.74) | ROCK1CYP3A4CYP2D6MYLKNFKB1 | |
| Hydrochloric Acid SCHEMBL1848494 | 0.84 | MAPK1 (1.00) | ROCK1CYP3A4CYP2D6MYLKNFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 233 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-121574883-A | Microbial preparation for straw decomposition and soil nutrient improvement and application thereof | 山东农业大学 | 2026-02-27 | — | — | CN | claimed |
| US-12533359-B2 | Method for preventing hair loss | ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (US) | 2026-01-27 | — | — | US | claimed |
| US-20260021190-A1 | GLUCOSE-RESPONSIVE INSULIN CONJUGATES COMPRISING A PENTA-VALENT SUGAR CLUSTER FOR TREATMENT OF DIABETES | MERCK SHARP & DOHME LLC (US) | 2026-01-22 | — | — | US | claimed |
| US-20250312332-A1 | TREATMENT OF MUSCLE FIBROSIS | FUNDACIÓ INSTITUT DE RECERCA DE L'HOSPITAL DE LA SANTA CREU I SANT PAU (ES) | 2025-10-09 | — | — | US | claimed |
| US-12427187-B2 | Glucose-responsive insulin conjugates | MERCK SHARP & DOHME LLC (US) | 2025-09-30 | — | — | US | claimed |
| EP-4615487-A1 | GLUCOSE-RESPONSIVE INSULIN CONJUGATES COMPRISING A PENTA-VALENT SUGAR CLUSTER FOR TREATMENT OF DIABETES | Merck Sharp & Dohme LLC (US) | 2025-09-17 | — | — | EP | claimed |
| EP-4615506-A1 | USE OF GSK-3 ACTIVATIOR TO MODULATE PROTEASOME ACTIVITY TO PREVENT AGEING ASSOCIATED CONDITIONS AND DISEASES | Sahin, Fikret (TR) | 2025-09-17 | — | — | EP | claimed |
| WO-2025118708-A1 | NUCLEIC ACID EXTRACTION METHOD FOR ENGINEERED CELL | 上海药明巨诺生物医药研发有限公司 | 2025-06-12 | — | — | WO | claimed |
| US-20250163388-A1 | METHODS FOR DERIVATION AND PROPAGATION OF AVIAN PLURIPOTENT STEM CELLS AND APPLICATIONS THEREOF | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2025-05-22 | — | — | US | claimed |
| CN-119913142-A | Composite microbial inoculum and preparation method and application thereof | 北京氢环能源技术有限公司 | 2025-05-02 | — | — | CN | claimed |
| CN-116297937-A | Method for detecting residual quantity of methyl sulfamate | 浙江国邦药业有限公司 | 2023-06-23 | — | — | CN | claimed |
| CN-116234911-A | Chimeric antigen receptor specifically binding MSLN and application thereof | 成都科伦精准生物科技有限公司 | 2023-06-06 | — | — | CN | claimed |
| WO-2023091441-A1 | GLUCOSE-RESPONSIVE INSULIN CONJUGATES COMPRISING A TETRA-VALENT SUGAR CLUSTER FOR TREATMENT OF DIABETES | MERCK SHARP & DOHME LLC (US) | 2023-05-25 | — | — | WO | claimed |
| WO-2022191812-A1 | METHOD OF FACILITATING WOUND-INDUCED HAIR FOLLICLE NEOGENESIS, TISSUE REGENERATION AND REDUCING WOUND STIFFNESS | NATIONAL CHENG KUNG UNIVERSITY (TW) | 2022-09-15 | — | — | WO | claimed |
| US-20220273770-A1 | GLUCOSE-RESPONSIVE INSULIN CONJUGATES | MERCK SHARP & DOHME CORP. (US) | 2022-09-01 | — | — | US | claimed |
| US-20220249509-A1 | METHOD FOR PREVENTING HAIR LOSS | ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (US) | 2022-08-11 | — | — | US | claimed |
| US-20220233647-A1 | GLUCOSE-RESPONSIVE INSULIN CONJUGATES | MERCK SHARP & DOHME CORP. (US) | 2022-07-28 | — | — | US | claimed |
| EP-4003405-A1 | GLUCOSE-RESPONSIVE INSULIN CONJUGATES | Merck Sharp & Dohme Corp. (US) | 2022-06-01 | — | — | EP | claimed |
| EP-3993764-A1 | METHOD FOR PREVENTING HAIR LOSS | Icahn School of Medicine at Mount Sinai (US) | 2022-05-11 | — | — | EP | claimed |
| EP-3980052-A1 | GLUCOSE-RESPONSIVE INSULIN CONJUGATES | MERCK SHARP & DOHME CORP. (US) | 2022-04-13 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250312332-A1 | TREATMENT OF MUSCLE FIBROSIS | RHOA, MYLK2, MYLK | ROCK1 4/4885CYP3A4 4737/4885CYP2D6 4664/4885 |
| US-12427187-B2 | Glucose-responsive insulin conjugates | GPR119, IRS1, INSR | ROCK1 3400/4885CYP3A4 2303/4885CYP2D6 1763/4885 |
| US-20220233647-A1 | GLUCOSE-RESPONSIVE INSULIN CONJUGATES | GPR119, IRS1, INSR | ROCK1 3400/4885CYP3A4 2303/4885CYP2D6 1763/4885 |
| US-20260021190-A1 | GLUCOSE-RESPONSIVE INSULIN CONJUGATES COMPRISING A PENTA-VALENT SUGAR CLUSTER FOR TREATMENT OF DIABETES | INSR, GPR119, GLP1R | ROCK1 2960/4885CYP3A4 611/4885CYP2D6 325/4885 |
| US-20220273770-A1 | GLUCOSE-RESPONSIVE INSULIN CONJUGATES | IRS1, GPR119, INSR | ROCK1 2566/4885CYP3A4 2224/4885CYP2D6 1180/4885 |
| US-12533359-B2 | Method for preventing hair loss | MYLK, MYLK3, MYLK2 | ROCK1 1070/4885CYP3A4 1847/4885CYP2D6 1337/4885 |
| US-20220249509-A1 | METHOD FOR PREVENTING HAIR LOSS | MYLK3, MYLK4, MYLK | ROCK1 34/4885CYP3A4 4728/4885CYP2D6 4103/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.