Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARA | P10276 | 18/20 | 0.43 |
| ▸ | RARB | P10826 | 18/20 | 0.43 |
| ▸ | RARG | P13631 | 18/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21562101 | 1.00 | RARA (0.43) | RARARARBRARGMCL1 | |
| SCHEMBL17843583 | 0.83 | RARA (0.50) | RARARARBRARGMCL1 | |
| SCHEMBL23691679 | 0.79 | MAPT (0.49) | RARARARBRARG | |
| SCHEMBL17843524 | 0.77 | MAPT (0.48) | RARARARBRARG | |
| SCHEMBL17843596 | 0.77 | RARA (0.43) | RARARARBRARGMCL1 | |
| SCHEMBL29475287 | 0.77 | MAPT (0.48) | RARARARBRARG | |
| SCHEMBL7135583 | 0.77 | RARA (0.40) | RARARARBRARGMCL1 | |
| SCHEMBL17843581 | 0.76 | RARA (0.42) | RARARARBRARG | |
| SCHEMBL24522302 | 0.76 | AKR1B1 (0.49) | RARARARBRARG | |
| SCHEMBL4508415 | 0.75 | MAOB (0.47) | MCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113950476-B | Substituted 4- [5- (benzofuran-2-yl) -1,2, 4-oxadiazol-3-yl ] benzoic acid compounds for the treatment of neuropathic pain | 伦敦皇家学院 | 2024-08-16 | — | — | CN | disclosed |
| US-11584741-B2 | Crystalline forms of 4-(5-(4,7-dimethylbenzofuran-2-yl)-1,2,4-oxadiazol-3-yl)benzoic acid and processes for their preparation | KING'S COLLEGE LONDON (GB) | 2023-02-21 | — | — | US | disclosed |
| US-20220204490-A1 | Substituted 4-[5-(Benzofuran-2-yl)-1,2,4-Oxadiazol-3-yl]Benzoic Acid Compounds for Use in Therapy for Neuropathic Pain | KING'S COLLEGE LONDON (GB) | 2022-06-30 | — | — | US | disclosed |
| EP-3976028-A1 | SUBSTITUTED 4-[5-(BENZOFURAN-2-YL)-1,2,4-OXADIAZOL-3-YL]BENZOIC ACID COMPOUNDS FOR USE IN THERAPY FOR NEUROPATHIC PAIN | King's College London (GB) | 2022-04-06 | — | — | EP | disclosed |
| CN-109415356-B | Crystalline forms of 4- (5- (4, 7-dimethylbenzofuran-2-yl) -1,2, 4-oxadiazol-3-yl) benzoic acid and methods for their preparation | 伦敦皇家学院 | 2022-03-08 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11584741-B2 | Crystalline forms of 4-(5-(4,7-dimethylbenzofuran-2-yl)-1,2,4-oxadiazol-3-yl)benzoic acid and processes for their preparation | RARB, RXRB, RARA | RARA 3/4885RARB 1/4885RARG 4/4885 |
| US-20220204490-A1 | Substituted 4-[5-(Benzofuran-2-yl)-1,2,4-Oxadiazol-3-yl]Benzoic Acid Compounds for Use in Therapy for Neuropathic Pain | OPRK1, TRPV1, TRPA1 | RARA 826/4885RARB 936/4885RARG 1233/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.