Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | IKBKB | O14920 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MLNR | O43193 | 1/20 | 0.34 |
| ▸ | MMP1 | P03956 | 1/20 | 0.34 |
| ▸ | MPO | P05164 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29397232 | 0.82 | MEN1 (0.44) | LMNAMEN1KMT2AGCK | |
| SCHEMBL28707073 | 0.81 | KDM4E (0.39) | KDM4ELMNAHTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL28706559 | 0.79 | NOS3 (0.42) | KDM4ELMNAHTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL29394408 | 0.79 | NOS3 (0.42) | KDM4ELMNAHTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL29397856 | 0.78 | PDE7A (0.45) | KDM4ELMNAHTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL28708361 | 0.78 | PDE7A (0.45) | KDM4ELMNAHTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL2566864 | 0.78 | SMN1; SMN2 (0.47) | LMNASMN1; SMN2ALDH1A1MAPTMEN1 | |
| SCHEMBL28690813 | 0.74 | NPC1 (0.43) | LMNASMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL2559700 | 0.70 | MAPK14 (0.46) | LMNAMEN1KMT2AGCK | |
| SCHEMBL28708289 | 0.70 | TDP1 (0.41) | HTTALDH1A1MAPTHPGDMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114144410-A | Polyarylurea derivatives and their use in the treatment of muscular diseases | 阿纳格纳斯生物技术股份有限公司 | 2022-03-04 | — | — | CN | disclosed |