Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 7/20 | 0.44 |
| ▸ | BRAF | P15056 | 10/20 | 0.43 |
| ▸ | GCK | P35557 | 1/20 | 0.43 |
| ▸ | LCK | P06239 | 1/20 | 0.42 |
| ▸ | FYN | P06241 | 1/20 | 0.42 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.42 |
| ▸ | KIT | P10721 | 1/20 | 0.42 |
| ▸ | SRC | P12931 | 1/20 | 0.42 |
| ▸ | FLT1 | P17948 | 1/20 | 0.42 |
| ▸ | FLT4 | P35916 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | MAPK13 | O15264 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2566864 | 0.86 | SMN1; SMN2 (0.47) | MEN1KMT2AMAPK14GCKKDR | |
| SCHEMBL23795609 | 0.83 | HTT (0.49) | MEN1KMT2AMAPK14BRAFGCK | |
| SCHEMBL29396629 | 0.82 | KDM4E (0.38) | MEN1KMT2AGCKLMNA | |
| SCHEMBL13788542 | 0.82 | HTT (0.56) | MEN1KMT2AMAPK14BRAFGCK | |
| SCHEMBL28690813 | 0.82 | NPC1 (0.43) | MEN1KMT2AMAPK14BRAFGCK | |
| SCHEMBL28700812 | 0.81 | MAPK14 (0.47) | MAPK14BRAFGCKLCKFYN | |
| SCHEMBL2559700 | 0.81 | MAPK14 (0.46) | MEN1KMT2AMAPK14BRAFGCK | |
| SCHEMBL29394408 | 0.79 | NOS3 (0.42) | MEN1KMT2AMAPK14LMNA | |
| SCHEMBL28706559 | 0.79 | NOS3 (0.42) | MEN1KMT2AMAPK14LMNA | |
| SCHEMBL29083255 | 0.79 | MEN1 (0.45) | MEN1KMT2AMAPK14BRAFGCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114144410-A | Polyarylurea derivatives and their use in the treatment of muscular diseases | 阿纳格纳斯生物技术股份有限公司 | 2022-03-04 | — | — | CN | disclosed |