Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 6/20 | 0.43 |
| ▸ | GRN | P28799 | 1/20 | 0.40 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.40 |
| ▸ | RXRA | P19793 | 3/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 3/20 | 0.39 |
| ▸ | NR1H3 | Q13133 | 3/20 | 0.39 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | ABL2 | P42684 | 1/20 | 0.39 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | FLT3 | P36888 | 1/20 | 0.38 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.38 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1011502 | 1.00 | MAPK14 (0.43) | MAPK14GRNSORT1RXRANR1H2 | |
| SCHEMBL6676733 | 0.84 | RXRA (0.50) | RXRANR1H2NR1H3KDM4ETRPV1 | |
| SCHEMBL1013289 | 0.83 | ALDH1A1 (0.56) | MAPK14GRNSORT1MAPK11KDM4E | |
| SCHEMBL31388014 | 0.81 | MAPK14 (0.40) | MAPK14GRNSORT1MAPK11KDM4E | |
| SCHEMBL15007938 | 0.81 | GRN (0.43) | MAPK14GRNSORT1MAPK11KDM4E | |
| Hydrochloric Acid SCHEMBL1492473 | 0.81 | ALDH1A1 (0.55) | MAPK14GRNSORT1MAPK11KDM4E | |
| SCHEMBL1015406 | 0.81 | MAPK14 (0.40) | MAPK14GRNSORT1MAPK11KDM4E | |
| SCHEMBL4514356 | 0.81 | SRC (0.40) | MAPK14GRNSORT1MAPK11ABL1 | |
| SCHEMBL1408441 | 0.80 | MAPK14 (0.42) | MAPK14GRNSORT1MAPK11KDM4E | |
| SCHEMBL29394648 | 0.79 | NR1I2 (0.42) | MAPK14GRNSORT1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114144410-A | Polyarylurea derivatives and their use in the treatment of muscular diseases | 阿纳格纳斯生物技术股份有限公司 | 2022-03-04 | — | — | CN | disclosed |