Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 3/20 | 0.50 |
| ▸ | NR1H2 | P55055 | 3/20 | 0.50 |
| ▸ | NR1H3 | Q13133 | 3/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 5/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.45 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.45 |
| ▸ | MAT2A | P31153 | 2/20 | 0.43 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.37 |
| ▸ | GABRP | O00591 | 1/20 | 0.37 |
| ▸ | GABRD | O14764 | 1/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.37 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.37 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.37 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.37 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.37 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12982900 | 0.88 | PDPK1 (0.44) | RXRANR1H2NR1H3PTGS1PTGS2 | |
| SCHEMBL29397663 | 0.84 | MAPK14 (0.43) | RXRANR1H2NR1H3KDM4ETRPV1 | |
| SCHEMBL1011502 | 0.84 | MAPK14 (0.43) | RXRANR1H2NR1H3KDM4ETRPV1 | |
| SCHEMBL2257225 | 0.83 | RXRA (0.46) | RXRANR1H2NR1H3PTGS1PTGS2 | |
| SCHEMBL15478703 | 0.83 | RXRA (0.51) | RXRANR1H2NR1H3PTGS1PTGS2 | |
| SCHEMBL12982781 | 0.82 | RXRA (0.42) | RXRANR1H2NR1H3PTGS1PTGS2 | |
| SCHEMBL3308089 | 0.81 | ALDH1A1 (0.55) | RXRANR1H2NR1H3PTGS1PTGS2 | |
| SCHEMBL2257122 | 0.81 | RXRA (0.50) | RXRANR1H2NR1H3PTGS1PTGS2 | |
| SCHEMBL12911850 | 0.81 | RXRA (0.53) | RXRANR1H2NR1H3PTGS1PTGS2 | |
| SCHEMBL4434557 | 0.81 | RXRA (0.53) | RXRANR1H2NR1H3PTGS1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040235959-A1 | Insecticidal diamides | E. I. DU PONT DE NEMOURS AND COMPANY | 2004-11-25 | — | — | US | disclosed |
| EP-1427705-A2 | INSECTICIDAL DIAMIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2004-06-16 | — | — | EP | disclosed |
| US-20040063738-A1 | Substituted heterocyclic phthalic acid diamide arthropodicides | E.I. DU PONT DE NEMOURS AND COMPANY | 2004-04-01 | — | — | US | disclosed |
| WO-2003026415-A2 | INSECTICIDAL DIAMIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2003-04-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040063738-A1 | Substituted heterocyclic phthalic acid diamide arthropodicides | DDT, QDPR, DDX6 | RXRA 1630/4885NR1H2 4270/4885NR1H3 4602/4885 |
| US-20040235959-A1 | Insecticidal diamides | DDT, NRDC, NOXO1 | RXRA 1059/4885NR1H2 801/4885NR1H3 1302/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.