SCHEMBL29397986

SCHEMBL29397986

CS(=O)(=O)CC[C@H](NC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)O

nearest known ligand 0.60

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ CASP3 P42574 4/20 0.60
▸ TLR2 O60603 2/20 0.56
▸ MDM4 O15151 2/20 0.54
▸ TP53 P04637 2/20 0.54
▸ MDM2 Q00987 5/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3236374 1.00 CASP3 (0.60) CASP3TLR2MDM4TP53MDM2
SCHEMBL3673319 1.00 CASP3 (0.60) CASP3TLR2MDM4TP53MDM2
SCHEMBL3378520 1.00 CASP3 (0.60) CASP3TLR2MDM4TP53MDM2
SCHEMBL30802531 1.00 CASP3 (0.60) CASP3TLR2MDM4TP53MDM2
SCHEMBL31538719 0.90 CASP3 (0.55) CASP3TLR2MDM4TP53MDM2
SCHEMBL19542133 0.90 CASP3 (0.55) CASP3TLR2MDM4TP53MDM2
SCHEMBL7713104 0.88 CASP3 (0.62) CASP3TLR2MDM4TP53MDM2
SCHEMBL7726774 0.88 CASP3 (0.62) CASP3TLR2MDM4TP53MDM2
SCHEMBL120255 0.88 TLR2 (0.59) CASP3TLR2MDM4TP53MDM2
SCHEMBL7532853 0.88 TLR2 (0.59) CASP3TLR2MDM4TP53MDM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117510576-A Method for preparing palmitoyl tripeptide-38 富乐马鸿凯(大连)医药有限公司 2024-02-06 — — CN claimed
EP-4748847-A1 PEPTIDE COMPLEX HAVING VEGFR -2 AGONIST ACTIVITY Peptidream Inc (JP) 2026-05-27 — — EP disclosed
US-12415835-B2 Peptide-compound cyclization method CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2025-09-16 — — US disclosed
US-20250263440-A1 CD38-BINDING AGENTS AND USES THEREOF PEPTIDREAM INC. (JP) 2025-08-21 — — US disclosed
US-12371454-B2 Cyclic peptide compound having Kras inhibitory action CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2025-07-29 — — US disclosed
US-20250171494-A1 METHOD FOR SYNTHESIZING PEPTIDE CONTAINING N-SUBSTITUTED AMINO ACID CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2025-05-29 — — US disclosed
CN-119954773-A PSMA compounds, pharmaceutical compositions comprising the same and uses thereof 苏州威智创科生物有限公司 2025-05-09 — — CN disclosed
CN-119954906-A CD38 binding agents and uses thereof 肽梦想株式会社 2025-05-09 — — CN disclosed
WO-2025092841-A1 PSMA COMPOUND, AND PHARMACEUTICAL COMPOSITION CONTAINING SAME AND USE THEREOF 山东威智知科药业有限公司 2025-05-08 — — WO disclosed
US-12281141-B2 Method for synthesizing peptide containing N-substituted amino acid CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2025-04-22 — — US disclosed
US-20230138226-A1 METHOD FOR SYNTHESIZING PEPTIDE CONTAINING N-SUBSTITUTED AMINO ACID CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2023-05-04 — — US disclosed
WO-2023075435-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE 주식회사 베르티스 2023-05-04 — — WO disclosed
US-11542299-B2 Method for synthesizing peptide containing N-substituted amino acid CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2023-01-03 — — US disclosed
WO-2022260135-A1 METHOD FOR PRODUCING FLUORESCENT PROBE LIBRARY USING SOLID-PHASE EXTRACTION AND METHOD OF MEASURING ENZYME ACTIVITY USING SAME 国立大学法人 東京大学 2022-12-15 — — WO disclosed
WO-2022234852-A1 PHARMACEUTICAL USE OF CYCLIC PEPTIDE COMPOUND 中外製薬株式会社 2022-11-10 — — WO disclosed
US-20220283131-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTES BERTIS CO., LTD. (KR) 2022-09-08 — — US disclosed
EP-4043478-A1 CYCLIC PEPTIDE COMPOUND HAVING KRAS INHIBITING ACTION CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2022-08-17 — — EP disclosed
EP-3993874-A1 CD38-BINDING AGENTS AND USES THEREOF PeptiDream Inc. (JP) 2022-05-11 — — EP disclosed
EP-3974563-A1 CYCLIC PEPTIDES Chugai Seiyaku Kabushiki Kaisha (JP) 2022-03-30 — — EP disclosed
WO-2022050529-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE ㈜베르티스 2022-03-10 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250171494-A1 METHOD FOR SYNTHESIZING PEPTIDE CONTAINING N-SUBSTITUTED AMINO ACID NPPA, VIP, DNPEP CASP3 1091/4885TLR2 4042/4885MDM4 4142/4885
US-20250263440-A1 CD38-BINDING AGENTS AND USES THEREOF CD38, IGSF11, MCL1 CASP3 2781/4885TLR2 3833/4885MDM4 1302/4885
US-12281141-B2 Method for synthesizing peptide containing N-substituted amino acid NPPA, VIP, DNPEP CASP3 1091/4885TLR2 4042/4885MDM4 4142/4885
US-20230138226-A1 METHOD FOR SYNTHESIZING PEPTIDE CONTAINING N-SUBSTITUTED AMINO ACID NPPA, VIP, DNPEP CASP3 1091/4885TLR2 4042/4885MDM4 4142/4885
US-11542299-B2 Method for synthesizing peptide containing N-substituted amino acid NPPA, VIP, DNPEP CASP3 1091/4885TLR2 4042/4885MDM4 4142/4885
US-12371454-B2 Cyclic peptide compound having Kras inhibitory action KRAS, NRAS, HRAS CASP3 3906/4885TLR2 3821/4885MDM4 441/4885
US-12415835-B2 Peptide-compound cyclization method VIP, NGLY1, GLP1R CASP3 343/4885TLR2 3462/4885MDM4 3559/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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