Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS2R8 | Q9NYW2 | 10/20 | 0.35 |
| ▸ | PPARD | Q03181 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | LIPE | Q05469 | 3/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.33 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.32 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.32 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.32 |
| ▸ | CACNA2D2 | Q9NY47 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.31 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2939817 | 0.87 | IGF1R (0.36) | TAS2R8PPARDPPARADPP4DPP7 | |
| SCHEMBL2941037 | 0.85 | TAS2R8 (0.41) | TAS2R8PPARDPPARAPOLBL3MBTL1 | |
| SCHEMBL2940720 | 0.83 | IGF1R (0.42) | TAS2R8 | |
| SCHEMBL2941133 | 0.83 | IGF1R (0.40) | LIPENPBWR1MCHR1HCRTR1HCRTR2 | |
| SCHEMBL2941640 | 0.83 | HCRTR1 (0.38) | PPARDPPARACACNA2D1POLBHCRTR1 | |
| SCHEMBL2939830 | 0.82 | KCNH2 (0.41) | MCHR1 | |
| SCHEMBL2940197 | 0.82 | PPARD (0.38) | TAS2R8PPARDPPARALIPENPBWR1 | |
| SCHEMBL2941225 | 0.81 | AOC1 (0.39) | TAS2R8PPARDPPARALIPENPBWR1 | |
| SCHEMBL2936420 | 0.81 | PPARD (0.37) | TAS2R8PPARDPPARALIPENPBWR1 | |
| SCHEMBL2937375 | 0.81 | PPARD (0.39) | TAS2R8PPARDPPARALIPEPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1599464-B1 | NOVEL CYCLIC UREA DERIVATIVES, PREPARATION METHOD THEREOF AND PHARMACEUTICAL USE OF SAME AS KINASE INHIBITORS | AVENTIS PHARMA SA (FR) | 2010-09-22 | — | — | EP | disclosed |