SCHEMBL29398684

SCHEMBL29398684

CC[C@@H](C)[C@@H](NC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)O

nearest known ligand 0.55

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CASP3 P42574 4/20 0.52
MDM4 O15151 2/20 0.49
TP53 P04637 2/20 0.49
KMT2A Q03164 2/20 0.49
PIN1 Q13526 1/20 0.48
CYP2C9 P11712 2/20 0.48
CYP2C19 P33261 2/20 0.48
CYP3A4 P08684 1/20 0.47
CYP2D6 P10635 1/20 0.47
RAB9A P51151 1/20 0.47
MDM2 Q00987 1/20 0.46
EPHX2 P34913 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29355117 1.00 CASP3 (0.52) CASP3MDM4TP53KMT2APIN1
SCHEMBL29398212 1.00 CASP3 (0.52) CASP3MDM4TP53KMT2APIN1
SCHEMBL30896049 1.00 CASP3 (0.52) CASP3MDM4TP53KMT2APIN1
SCHEMBL1486287 1.00 CASP3 (0.52) CASP3MDM4TP53KMT2APIN1
SCHEMBL1486214 1.00 CASP3 (0.52) CASP3MDM4TP53KMT2APIN1
SCHEMBL118209 1.00 CASP3 (0.52) CASP3MDM4TP53KMT2APIN1
SCHEMBL119497 1.00 CASP3 (0.52) CASP3MDM4TP53KMT2APIN1
SCHEMBL30896048 1.00 CASP3 (0.52) CASP3MDM4TP53KMT2APIN1
SCHEMBL6038102 1.00 CASP3 (0.52) CASP3MDM4TP53KMT2APIN1
SCHEMBL1564185 1.00 CASP3 (0.52) CASP3MDM4TP53KMT2APIN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117417402-A Pseudo dandelion sterol derivative and preparation method and application thereof 天津科技大学 2024-01-19 CN claimed
EP-4720097-A1 PEPTIDES WITH LIPOLYTIC, ANTI-LIPOGENIC, ANTIFIBROTIC AND ANTI-INFLAMMATORY ACTIVITY Fundació Hospital Universitari Vall d'Hebron - Institut de Recerca (ES) 2026-04-08 EP disclosed
EP-4685154-A1 POLYPEPTIDE DERIVED FROM TRIDEGIN Rheinische Friedrich-Wilhelms-Universität Bonn (DE) 2026-01-28 EP disclosed
EP-4673554-A1 ASPARAGINYL PEPTIDE LIGASE-MEDIATED RADIOLABELLING OF SINGLE-DOMAIN ANTIBODIES Nanyang Technological University (SG) 2026-01-07 EP disclosed
US-20260001928-A1 CRF2 RECEPTOR AGONISTS AND THEIR USE IN THERAPY CORTERIA PHARMACEUTICALS (FR) 2026-01-01 US disclosed
EP-4482578-B1 CRF2 RECEPTOR AGONISTS AND THEIR USE IN THERAPY CORTERIA PHARMACEUTICALS (FR) 2025-12-24 EP disclosed
US-12458685-B2 Manufacture, formulation and dosing of apraglutide VECTIVBIO AG (CH) 2025-11-04 US disclosed
US-12410212-B2 Cyclic compound having selective KRAS inhibitory effect on HRAS and NRAS CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2025-09-09 US disclosed
US-20250230193-A1 CYCLIC COMPOUND HAVING SELECTIVE KRAS INHIBITORY EFFECT ON HRAS AND NRAS CHUGAI PHARMACEUTICAL CO LTD (JP) 2025-07-17 US disclosed
US-20250186557-A1 MANUFACTURE, FORMULATION AND DOSING OF APRAGLUTIDE VECTIVBIO AG (CH) 2025-06-12 US disclosed
CN-115389693-A Detection method for simultaneously determining various side chain protection amino acid isomers by HPLC 河北科技大学 2022-11-25 CN disclosed
US-20220283131-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTES BERTIS CO., LTD. (KR) 2022-09-08 US disclosed
CN-114989298-A D-peptide compounds against VEGF 反射制药有限公司 2022-09-02 CN disclosed
CN-114874293-A Cyclic polypeptide compounds and preparation method and application thereof 中国医学科学院医药生物技术研究所 2022-08-09 CN disclosed
WO-2022162332-A1 ANTIBIOTIC NATURAL PRODUCT ANALOGUES THE QUEEN'S UNIVERSITY OF BELFAST (GB) 2022-08-04 WO disclosed
CN-112500457-B Dual-targeting FOXM1/CDK1 anti-tumor polypeptide 长沙新生康源生物医药有限公司 2022-06-17 CN disclosed
CN-114174334-A D-peptide compounds against VEGF 反射制药有限公司 2022-03-11 CN disclosed
WO-2022050529-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE ㈜베르티스 2022-03-10 WO disclosed
CN-114144433-A Multivalent D-peptide compounds for proteins of interest 反射制药有限公司 2022-03-04 CN disclosed
US-20220062384-A1 MANUFACTURE, FORMULATION AND DOSING OF APRAGLUTIDE VECTIVBIO AG (CH) 2022-03-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220062384-A1 MANUFACTURE, FORMULATION AND DOSING OF APRAGLUTIDE GLP1R, IAPP, GIPR CASP3 329/4885MDM4 4715/4885TP53 4243/4885
US-20250186557-A1 MANUFACTURE, FORMULATION AND DOSING OF APRAGLUTIDE GLP1R, IAPP, GIPR CASP3 329/4885MDM4 4715/4885TP53 4243/4885
US-12410212-B2 Cyclic compound having selective KRAS inhibitory effect on HRAS and NRAS KRAS, HRAS, NRAS CASP3 2833/4885MDM4 455/4885TP53 8/4885
US-12458685-B2 Manufacture, formulation and dosing of apraglutide GLP1R, IAPP, GIPR CASP3 329/4885MDM4 4715/4885TP53 4243/4885
US-20250230193-A1 CYCLIC COMPOUND HAVING SELECTIVE KRAS INHIBITORY EFFECT ON HRAS AND NRAS KRAS, HRAS, NRAS CASP3 2833/4885MDM4 455/4885TP53 8/4885
US-20260001928-A1 CRF2 RECEPTOR AGONISTS AND THEIR USE IN THERAPY GIPR, NPY2R, NPY1R CASP3 4474/4885MDM4 4186/4885TP53 4581/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.