SCHEMBL6038102

SCHEMBL6038102

CC[C@@H](C)[C@H](NC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)O

nearest known ligand 0.55

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CASP3 P42574 4/20 0.52
MDM4 O15151 2/20 0.49
TP53 P04637 2/20 0.49
KMT2A Q03164 2/20 0.49
PIN1 Q13526 1/20 0.48
CYP2C9 P11712 2/20 0.48
CYP2C19 P33261 2/20 0.48
CYP3A4 P08684 1/20 0.47
CYP2D6 P10635 1/20 0.47
RAB9A P51151 1/20 0.47
MDM2 Q00987 1/20 0.46
EPHX2 P34913 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29355117 1.00 CASP3 (0.52) CASP3MDM4TP53KMT2APIN1
SCHEMBL29398212 1.00 CASP3 (0.52) CASP3MDM4TP53KMT2APIN1
SCHEMBL30896049 1.00 CASP3 (0.52) CASP3MDM4TP53KMT2APIN1
SCHEMBL1486287 1.00 CASP3 (0.52) CASP3MDM4TP53KMT2APIN1
SCHEMBL1486214 1.00 CASP3 (0.52) CASP3MDM4TP53KMT2APIN1
SCHEMBL118209 1.00 CASP3 (0.52) CASP3MDM4TP53KMT2APIN1
SCHEMBL119497 1.00 CASP3 (0.52) CASP3MDM4TP53KMT2APIN1
SCHEMBL30896048 1.00 CASP3 (0.52) CASP3MDM4TP53KMT2APIN1
SCHEMBL1564185 1.00 CASP3 (0.52) CASP3MDM4TP53KMT2APIN1
SCHEMBL29398684 1.00 CASP3 (0.52) CASP3MDM4TP53KMT2APIN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 71 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4748847-A1 PEPTIDE COMPLEX HAVING VEGFR -2 AGONIST ACTIVITY Peptidream Inc (JP) 2026-05-27 EP disclosed
EP-3681875-B1 CYCLIC PEPTIDE ANTIBIOTICS HOFFMANN LA ROCHE (CH) 2026-01-14 EP disclosed
US-20250362310-A1 STRUCTURE-BASED PROBE FOR DETECTION OF TRANSTHYRETIN AMYLOID FIBRILS AND AGGREGATES THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) 2025-11-27 US disclosed
EP-4631955-A1 PURIFICATION METHOD AND PRODUCTION METHOD OF CYCLIC PEPTIDE CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2025-10-15 EP disclosed
US-12410212-B2 Cyclic compound having selective KRAS inhibitory effect on HRAS and NRAS CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2025-09-09 US disclosed
US-12404299-B2 Method for producing peptide compound comprising highly sterically hindered amino acid CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2025-09-02 US disclosed
US-20250257094-A1 METHODS FOR PRODUCING CYCLIC COMPOUNDS COMPRISING N-SUBSTITUTED AMINO ACID RESIDUES CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2025-08-14 US disclosed
US-12371454-B2 Cyclic peptide compound having Kras inhibitory action CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2025-07-29 US disclosed
US-20250230193-A1 CYCLIC COMPOUND HAVING SELECTIVE KRAS INHIBITORY EFFECT ON HRAS AND NRAS CHUGAI PHARMACEUTICAL CO LTD (JP) 2025-07-17 US disclosed
CN-111148739-B Cyclic peptide antibiotics 豪夫迈·罗氏有限公司 2025-06-03 CN disclosed
WO-2017096311-A1 CONJUGATES OF QUATERNIZED TUBULYSIN COMPOUNDS SEATTLE GENETICS, INC. (US) 2017-06-08 WO disclosed
US-8466291-B2 1,5-dideoxy-1,5-imino-D-glucitol compounds ACADEMIA SINICA (TW) 2013-06-18 US disclosed
WO-2012101612-A1 FMOC SOLID PHASE PEPTIDE SYNTHESIS ON BIODEGRADABLE SUPPORT AND USES THEREOF The National Institute for Biotechnology in the Negev Ltd. (IL) 2012-08-02 WO disclosed
US-20100113519-A1 1,5-Dideoxy-1,5-imino-D-glucitol Compounds ACADEMIA SINICA (TW) 2010-05-06 US disclosed
US-20100113519-A1 1,5-Dideoxy-1,5-imino-D-glucitol Compounds ACADEMIA SINICA (TW) 2010-05-06 US disclosed
US-20060275213-A1 Tumor targeting agents and uses thereof KARYON OY (FI) 2006-12-07 US disclosed
CN-1720258-A Tumor targeting agents and uses thereof KARYON OY (FI) 2006-01-11 CN disclosed
EP-1549669-A1 TUMOR TARGETING AGENTS AND USES THEREOF Karyon OY (FI) 2005-07-06 EP disclosed
WO-2004031221-A9 TUMOR TARGETING AGENTS AND USES THEREOF KARYON OY (FI) 2004-07-08 WO disclosed
WO-2004031221-A1 TUMOR TARGETING AGENTS AND USES THEREOF KARYON OY (FI) 2004-04-15 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12410212-B2 Cyclic compound having selective KRAS inhibitory effect on HRAS and NRAS KRAS, HRAS, NRAS CASP3 2833/4885MDM4 455/4885TP53 8/4885
US-20060275213-A1 Tumor targeting agents and uses thereof CCL2, CCL5, SCTR CASP3 1215/4885MDM4 901/4885TP53 46/4885
US-12404299-B2 Method for producing peptide compound comprising highly sterically hindered amino acid DNPEP, VIP, NPEPPS CASP3 1864/4885MDM4 3528/4885TP53 1753/4885
US-20250230193-A1 CYCLIC COMPOUND HAVING SELECTIVE KRAS INHIBITORY EFFECT ON HRAS AND NRAS KRAS, HRAS, NRAS CASP3 2833/4885MDM4 455/4885TP53 8/4885
US-20250257094-A1 METHODS FOR PRODUCING CYCLIC COMPOUNDS COMPRISING N-SUBSTITUTED AMINO ACID RESIDUES NGLY1, NPPA, VIP CASP3 1858/4885MDM4 266/4885TP53 300/4885
US-12371454-B2 Cyclic peptide compound having Kras inhibitory action KRAS, NRAS, HRAS CASP3 3906/4885MDM4 441/4885TP53 34/4885
US-20100113519-A1 1,5-Dideoxy-1,5-imino-D-glucitol Compounds HEXD, GALE, GBA1 CASP3 3082/4885MDM4 4770/4885TP53 4437/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.