SCHEMBL119497

SCHEMBL119497

CC[C@H](C)[C@H](NC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)O

nearest known ligand 0.55

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CASP3 P42574 4/20 0.52
MDM4 O15151 2/20 0.49
TP53 P04637 2/20 0.49
KMT2A Q03164 2/20 0.49
PIN1 Q13526 1/20 0.48
CYP2C9 P11712 2/20 0.48
CYP2C19 P33261 2/20 0.48
CYP3A4 P08684 1/20 0.47
CYP2D6 P10635 1/20 0.47
RAB9A P51151 1/20 0.47
MDM2 Q00987 1/20 0.46
EPHX2 P34913 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29355117 1.00 CASP3 (0.52) CASP3MDM4TP53KMT2APIN1
SCHEMBL29398212 1.00 CASP3 (0.52) CASP3MDM4TP53KMT2APIN1
SCHEMBL30896049 1.00 CASP3 (0.52) CASP3MDM4TP53KMT2APIN1
SCHEMBL1486287 1.00 CASP3 (0.52) CASP3MDM4TP53KMT2APIN1
SCHEMBL1486214 1.00 CASP3 (0.52) CASP3MDM4TP53KMT2APIN1
SCHEMBL118209 1.00 CASP3 (0.52) CASP3MDM4TP53KMT2APIN1
SCHEMBL30896048 1.00 CASP3 (0.52) CASP3MDM4TP53KMT2APIN1
SCHEMBL6038102 1.00 CASP3 (0.52) CASP3MDM4TP53KMT2APIN1
SCHEMBL1564185 1.00 CASP3 (0.52) CASP3MDM4TP53KMT2APIN1
SCHEMBL29398684 1.00 CASP3 (0.52) CASP3MDM4TP53KMT2APIN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 219 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116773724-A High performance liquid chromatography for simultaneously detecting fluorenylmethoxycarbonyl-L-isoleucine and four impurity amino acids thereof 成都郑源生化科技有限公司 2023-09-19 CN claimed
CN-116606348-A Self-assembled supermolecule nano material responding to AXL kinase and preparation method and application thereof 东南大学 2023-08-18 CN claimed
CN-116425827-A Short peptide Fmoc-L-Ile-Aib-OH and preparation method thereof 成都郑源生化科技有限公司 2023-07-14 CN claimed
CN-112430588-B Short peptide for resisting novel coronavirus infection and preparation method and application thereof 中国人民解放军陆军军医大学 2022-12-30 CN claimed
CN-113072620-B PD-1 targeting peptide with analgesic activity, and synthesis method and application thereof 南通大学 2022-07-05 CN claimed
EP-3988538-A1 MODIFIED HYDROPHOBIC AUXILIARY MATERIAL, PREPARATION METHOD THEREFOR AND USE THEREOF Zhejiang Zhida Pharmaceutical Co., Ltd. (CN) 2022-04-27 EP claimed
US-20220111055-A1 MODIFIED HYDROPHOBIC EXCIPIENT AND PREPARATION METHOD THEREOF ZHEJIANG ZHIDA PHARMACEUTICAL CO., LTD. (CN) 2022-04-14 US claimed
CN-113072620-A PD-1 targeting peptide with analgesic activity, and synthesis method and application thereof 南通大学 2021-07-06 CN claimed
CN-112430588-A Short peptide for resisting novel coronavirus infection and preparation method and application thereof 中国人民解放军陆军军医大学 2021-03-02 CN claimed
CN-112110834-A Modified hydrophobic auxiliary material and preparation method and application thereof 浙江智达药业有限公司 2020-12-22 CN claimed
CN-105777866-A Anti-hypertension bioactive peptide and preparing method thereof 南京大学 2016-07-20 CN claimed
CN-102786579-B Antihypertensive active peptide VIP UNIV SHANGHAI JIAOTONG 2014-07-09 CN claimed
CN-102702343-A Method for synthesizing tesamorelin through solid phases GL BIOCHEM SHANGHAI CO LTD 2012-10-03 CN claimed
CN-102443048-A Synthetic method of 5-membered cyclopeptide JIANGSU YEW PHARMACEUTICAL CO LTD 2012-05-09 CN claimed
CN-100590068-C Method for preparing primary amine carbon nano tube UNIV TONGJI 2010-02-17 CN claimed
CN-101177259-A Method for preparing primary amine carbon nano tube UNIV TONGJI (CN) 2008-05-14 CN claimed
US-12616676-B2 Preparation method and use of modified hydrophobic excipient ZHEJIANG ZHIDA PHARMACEUTICAL CO., LTD. (CN) 2026-05-05 US disclosed
EP-3966226-B1 MASP INHIBITORY COMPOUNDS AND USES THEREOF BAYER AG (DE) 2025-12-24 EP disclosed
WO-1997019681-A1 PERFLUOROALKYL SUBSTITUTED METALLO-BETA-LACTAMASE INHIBITORS AND METHOD FOR THE PREPARATION OF TRIFLUOROMETHYLKETONE DERIVATIVES ISIS INNOVATION LIMITED (GB) 1997-06-05 WO disclosed
EP-0346108-A2 Anti-infective nucleosides THE WELLCOME FOUNDATION LIMITED (GB) 1989-12-13 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12616676-B2 Preparation method and use of modified hydrophobic excipient CETP, LIPA, MTTP CASP3 1489/4885MDM4 3741/4885TP53 1141/4885
US-20220111055-A1 MODIFIED HYDROPHOBIC EXCIPIENT AND PREPARATION METHOD THEREOF CETP, SLC43A1, SLC27A1 CASP3 2158/4885MDM4 884/4885TP53 403/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.