Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGF1R | P08069 | 2/20 | 0.32 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2938270 | 0.85 | ACACB (0.37) | — | |
| SCHEMBL2938561 | 0.83 | IGF1R (0.42) | IGF1RMEN1KMT2A | |
| SCHEMBL2940492 | 0.82 | IGF1R (0.42) | IGF1RMEN1KMT2A | |
| SCHEMBL2939364 | 0.81 | CNR2 (0.39) | IGF1RKMT2A | |
| SCHEMBL2941032 | 0.81 | ATM (0.35) | IGF1RMEN1KMT2ALMNAMAPK1 | |
| SCHEMBL6174951 | 0.80 | KDM4E (0.40) | IGF1RLMNAMAPK1HTTSMN1; SMN2 | |
| SCHEMBL2939980 | 0.68 | CTSD (0.37) | IGF1R | |
| SCHEMBL6172554 | 0.68 | IGF1R (0.33) | IGF1RLMNAMAPK1HTTSMN1; SMN2 | |
| SCHEMBL2938254 | 0.68 | LMNA (0.34) | IGF1RLMNAMAPK1HTTSMN1; SMN2 | |
| SCHEMBL2939428 | 0.68 | ACACB (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1599464-B1 | NOVEL CYCLIC UREA DERIVATIVES, PREPARATION METHOD THEREOF AND PHARMACEUTICAL USE OF SAME AS KINASE INHIBITORS | AVENTIS PHARMA SA (FR) | 2010-09-22 | — | — | EP | disclosed |