SCHEMBL29399358

SCHEMBL29399358

CCCC[C@H](N)C(=O)N[C@@H](CS)C(=O)O

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ DPP7 Q9UHL4 9/20 0.54
▸ DPP9 Q86TI2 8/20 0.54
▸ DPP8 Q6V1X1 7/20 0.54
▸ DPP4 P27487 5/20 0.54
▸ ACE P12821 1/20 0.53
▸ SLC15A1 P46059 1/20 0.50
▸ KDM4E B2RXH2 1/20 0.49
▸ MAPT P10636 1/20 0.49
▸ THRB P10828 1/20 0.49
▸ ALOX15 P16050 1/20 0.49
▸ NFKB1 P19838 1/20 0.49
▸ PTGS2 P35354 1/20 0.49
▸ THPO P40225 1/20 0.49
▸ RECQL P46063 1/20 0.49
▸ BLM P54132 1/20 0.49
▸ SMN1; SMN2 Q16637 1/20 0.49
▸ MME P08473 1/20 0.48
▸ NOD1 Q9Y239 3/20 0.46
▸ SLC1A3 P43003 1/20 0.44
▸ SLC1A2 P43004 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30101956 0.90 FOLH1 (0.52) DPP7DPP9DPP8DPP4ACE
SCHEMBL31679398 0.90 ACE (0.56) DPP7DPP9DPP8DPP4ACE
SCHEMBL9052383 0.89 DPP7 (0.53) DPP7DPP9DPP8DPP4SLC15A1
SCHEMBL2850058 0.88 DPP7 (0.58) DPP7DPP9DPP8DPP4SLC15A1
SCHEMBL29376792 0.88 DPP7 (0.58) DPP7DPP9DPP8DPP4SLC15A1
SCHEMBL30954356 0.87 DPP7 (0.54) DPP7DPP9DPP8DPP4SLC15A1
SCHEMBL29397354 0.87 MME (0.54) DPP7DPP9DPP8DPP4ACE
SCHEMBL30833260 0.87 DPP7 (0.57) DPP7DPP9DPP8DPP4SLC15A1
SCHEMBL8497101 0.87 DPP7 (0.57) DPP7DPP9DPP8DPP4SLC15A1
SCHEMBL31433356 0.86 NOD1 (0.45) DPP7DPP9DPP8DPP4ACE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115746091-B High-stability collagen targeting SERS polypeptide probe and application thereof in liver fibrosis diagnosis 胶原蛋白(武汉)生物科技有限公司 2024-10-01 — — CN claimed
CN-115746091-A High-stability collagen targeted SERS polypeptide probe and application thereof in hepatic fibrosis diagnosis 胶原蛋白(武汉)生物科技有限公司 2023-03-07 — — CN claimed
US-20220339239-A1 USE OF MELANOCORTINS TO TREAT INSULIN SENSITIVITY IPSEN PHARMA SAS (FR) 2022-10-27 — — US claimed
US-20260085092-A1 MELANOCORTIN RECEPTOR LIGANDS IPSEN PHARMA SAS (FR) 2026-03-26 — — US disclosed
EP-4711004-A2 METHOD OF TREATING MELANOCORTIN-4 RECEPTOR PATHWAY-ASSOCIATED DISORDERS Rhythm Pharmaceuticals, Inc. (US) 2026-03-18 — — EP disclosed
US-20260001915-A1 METHODS FOR TREATING OBESITY WITH AN MC4R AGONIST RHYTHM PHARMACEUTICALS INC (US) 2026-01-01 — — US disclosed
EP-4618952-A2 METHODS FOR TREATING OBESITY WITH AN MC4R AGONIST Rhythm Pharmaceuticals, Inc. (US) 2025-09-24 — — EP disclosed
EP-4610269-A1 UROKINASE PLASMINOGEN ACTIVATOR SURFACE RECEPTOR (UPAR) LIGANDS FOR DIAGNOSTIC OR THERAPEUTIC USE 3B Pharmaceuticals GmbH (DE) 2025-09-03 — — EP disclosed
US-20250230483-A1 OCULAR INSERTS WITH PROTEASE SENSING INDICATORS TearDX LLC 2025-07-17 — — US disclosed
US-20250195606-A1 METHOD OF TREATING MELANOCORTIN-4 RECEPTOR PATHWAY-ASSOCIATED DISORDERS CHARITÉ - UNIVERSITÄTSMEDIZIN BERLIN (DE) 2025-06-19 — — US disclosed
CN-120152725-A Methods of treating obesity using MC4R agonists 节奏制药公司 2025-06-13 — — CN disclosed
CN-114981310-A Whole-process targeting molecule and application of drug compound thereof in construction of drug delivery system 复旦大学 2022-08-30 — — CN disclosed
EP-4029513-A1 MELANOCORTIN-4 RECEPTOR AGONISTS FOR THE TREATMENT OF DISORDERS CHARACTERISED BY POMC GENE HYPERMETHYLATION Rhythm Pharmaceuticals, Inc. (US) 2022-07-20 — — EP disclosed
US-20220195035-A1 MONOCLONAL ANTIBODIES TO PROGASTRIN AND THEIR USES LES LABORATOIRES SERVIER (FR) 2022-06-23 — — US disclosed
US-20220127305-A1 MELANOCORTIN RECEPTOR LIGANDS IPSEN PHARMA SAS (FR) 2022-04-28 — — US disclosed
EP-3988108-A1 METHOD OF TREATING MELANOCORTIN-4 RECEPTOR-ASSOCIATED DISORDERS IN HETEROZYGOUS CARRIERS Rhythm Pharmaceuticals, Inc. (US) 2022-04-27 — — EP disclosed
US-11299542-B2 Monoclonal antibodies to progastrin and their uses LES LABORATORIES SERVIER (FR) 2022-04-12 — — US disclosed
WO-2022067086-A1 METHODS OF TREATING MELANOCORTIN-4 RECEPTOR PATHWAY-ASSOCIATED DISORDERS RHYTHM PHARMACEUTICALS, INC. (US) 2022-03-31 — — WO disclosed
US-11273223-B2 Bispecific anti-hapten/anti-blood brain barrier receptor antibodies, complexes thereof and their use as blood brain barrier shuttles HOFFMANN-LA ROCHE INC. (US) 2022-03-15 — — US disclosed
EP-3960768-A1 BISPECIFIC ANTI-HAPTEN/ANTI-BLOOD BRAIN BARRIER RECEPTOR ANTIBODIES, COMPLEXES THEREOF AND THEIR USE AS BLOOD BRAIN BARRIER SHUTTLES F. Hoffmann-La Roche AG (CH) 2022-03-02 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260001915-A1 METHODS FOR TREATING OBESITY WITH AN MC4R AGONIST MC4R, NPY4R, MC3R DPP7 1818/4885DPP9 945/4885DPP8 1558/4885
US-20260085092-A1 MELANOCORTIN RECEPTOR LIGANDS THRB, MC1R, MC5R DPP7 513/4885DPP9 1005/4885DPP8 780/4885
US-20220339239-A1 USE OF MELANOCORTINS TO TREAT INSULIN SENSITIVITY MC4R, MC1R, MC3R DPP7 228/4885DPP9 462/4885DPP8 264/4885
US-20250195606-A1 METHOD OF TREATING MELANOCORTIN-4 RECEPTOR PATHWAY-ASSOCIATED DISORDERS MC4R, MC5R, MC3R DPP7 2314/4885DPP9 2171/4885DPP8 1811/4885
US-20220127305-A1 MELANOCORTIN RECEPTOR LIGANDS MC3R, MC1R, MC5R DPP7 2695/4885DPP9 2769/4885DPP8 1670/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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