SCHEMBL29397354

SCHEMBL29397354

CCCC[C@H](NC(=O)[C@@H](N)CS)C(=O)O

nearest known ligand 0.54

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ MME P08473 1/20 0.54
▸ NOD1 Q9Y239 6/20 0.50
▸ FNTA P49354 3/20 0.48
▸ FNTB P49356 3/20 0.48
▸ PGGT1B P53609 1/20 0.48
▸ DPP4 P27487 4/20 0.46
▸ DPP9 Q86TI2 4/20 0.46
▸ DPP7 Q9UHL4 4/20 0.46
▸ DPP8 Q6V1X1 3/20 0.46
▸ ACE P12821 1/20 0.45
▸ CA2 P00918 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29585814 0.97 MME (0.52) MMENOD1FNTAFNTBPGGT1B
SCHEMBL30811192 0.90 FOLH1 (0.49) MMENOD1FNTAFNTBPGGT1B
SCHEMBL29454516 0.90 MME (0.46) MMENOD1FNTAFNTBPGGT1B
SCHEMBL30811169 0.89 NOD1 (0.47) MMENOD1FNTAFNTBPGGT1B
SCHEMBL29376792 0.88 DPP7 (0.58) NOD1DPP4DPP9DPP7DPP8
SCHEMBL2850058 0.88 DPP7 (0.58) NOD1DPP4DPP9DPP7DPP8
SCHEMBL29399358 0.87 DPP7 (0.54) MMENOD1DPP4DPP9DPP7
SCHEMBL29692729 0.87 DPP7 (0.59) MMENOD1DPP4DPP9DPP7
SCHEMBL9052383 0.86 DPP7 (0.53) MMENOD1DPP4DPP9DPP7
SCHEMBL29743020 0.85 CPB2 (0.49) NOD1FNTAFNTBPGGT1BACE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250074942-A1 COMPOSITIONS AND METHODS FOR COVALENT PEPTIDE-BASED MODULATORS OF HLA-E CALICO LIFE SCIENCES LLC (US) 2025-03-06 — — US disclosed
US-12023378-B2 Covalently linked antigen-antibody conjugates HOFFMANN-LA ROCHE INC. (US) 2024-07-02 — — US disclosed
CN-113087789-B Filamentous phage pVIII protein monoclonal antibody and application thereof 中国农业大学 2022-09-23 — — CN disclosed
US-11273223-B2 Bispecific anti-hapten/anti-blood brain barrier receptor antibodies, complexes thereof and their use as blood brain barrier shuttles HOFFMANN-LA ROCHE INC. (US) 2022-03-15 — — US disclosed
EP-3960768-A1 BISPECIFIC ANTI-HAPTEN/ANTI-BLOOD BRAIN BARRIER RECEPTOR ANTIBODIES, COMPLEXES THEREOF AND THEIR USE AS BLOOD BRAIN BARRIER SHUTTLES F. Hoffmann-La Roche AG (CH) 2022-03-02 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250074942-A1 COMPOSITIONS AND METHODS FOR COVALENT PEPTIDE-BASED MODULATORS OF HLA-E MICA, CD74, HLA-DRB1 MME 130/4885NOD1 1477/4885FNTA 3629/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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