Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCK | P35557 | 12/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.33 |
| ▸ | SYK | P43405 | 1/20 | 0.32 |
| ▸ | LCK | P06239 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29070858 | 0.86 | JAK3 (0.40) | L3MBTL1PDPK1ALDH1A1GPR119SYK | |
| SCHEMBL18786661 | 0.85 | L3MBTL1 (0.38) | L3MBTL1PDPK1ALDH1A1GPR119SYK | |
| SCHEMBL17369373 | 0.82 | ABL1 (0.46) | GPR119 | |
| SCHEMBL29070857 | 0.78 | GPR119 (0.48) | PDPK1GPR119 | |
| SCHEMBL30513344 | 0.76 | CDK9 (0.44) | GPR119 | |
| SCHEMBL29070854 | 0.75 | LCK (0.49) | PDPK1SYKLCK | |
| SCHEMBL23025029 | 0.75 | SSTR4 (0.36) | PDPK1ALDH1A1SYK | |
| SCHEMBL29400643 | 0.75 | PDPK1 (0.38) | PDPK1SYK | |
| SCHEMBL558081 | 0.75 | PDPK1 (0.38) | PDPK1SYK | |
| SCHEMBL15274739 | 0.75 | PDPK1 (0.40) | PDPK1ALDH1A1SYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4200296-A1 | MNK INHIBITORS | Hepagene Therapeutics (HK) Limited (HK) | 2023-06-28 | — | — | EP | disclosed |
| WO-2022038563-A1 | MNK INHIBITORS | Hepagene Therapeutics (HK) Limited (CN) | 2022-02-24 | — | — | WO | disclosed |