SCHEMBL29400442

SCHEMBL29400442

O=C(N[C@@H](Cc1cn(C(c2ccccc2)(c2ccccc2)c2ccccc2)cn1)C(=O)Oc1c(F)c(F)c(F)c(F)c1F)OCC1c2ccccc2-c2ccccc21

nearest known ligand 0.47

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ MDM4 O15151 3/20 0.47
▸ TP53 P04637 3/20 0.47
▸ SIRT2 Q8IXJ6 12/20 0.45
▸ MDM2 Q00987 2/20 0.42
▸ NMBR P28336 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30468161 0.90 SIRT2 (0.55) MDM4TP53SIRT2MDM2NMBR
SCHEMBL13227674 0.88 MDM4 (0.54) MDM4TP53SIRT2MDM2
SCHEMBL29368020 0.88 MDM4 (0.54) MDM4TP53SIRT2MDM2
SCHEMBL12994493 0.88 MDM4 (0.54) MDM4TP53SIRT2MDM2
SCHEMBL30433831 0.88 MDM4 (0.54) MDM4TP53SIRT2MDM2
SCHEMBL1737899 0.88 MDM4 (0.54) MDM4TP53SIRT2MDM2
SCHEMBL28625947 0.85 MDM2 (0.52) MDM4TP53SIRT2MDM2
SCHEMBL28625949 0.85 MDM2 (0.52) MDM4TP53SIRT2MDM2
SCHEMBL30434660 0.85 MDM2 (0.52) MDM4TP53SIRT2MDM2
SCHEMBL30385679 0.85 MDM4 (0.49) MDM4TP53SIRT2MDM2NMBR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4425181-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE Bertis Inc (KR) 2024-09-04 — — EP disclosed
US-20240011979-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTES BERTIS INC. (KR) 2024-01-11 — — US disclosed
CN-116829949-A Compositions for detecting or measuring analytes 伯蒂斯有限公司 2023-09-29 — — CN disclosed
WO-2023075435-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE 주식회사 베르티스 2023-05-04 — — WO disclosed
US-20220283131-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTES BERTIS CO., LTD. (KR) 2022-09-08 — — US disclosed
WO-2022050529-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE ㈜베르티스 2022-03-10 — — WO disclosed
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