Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 13/20 | 0.55 |
| ▸ | MDM4 | O15151 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.51 |
| ▸ | NMBR | P28336 | 1/20 | 0.45 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29368020 | 0.93 | MDM4 (0.54) | SIRT2MDM4TP53MDM2 | |
| SCHEMBL13227674 | 0.93 | MDM4 (0.54) | SIRT2MDM4TP53MDM2 | |
| SCHEMBL30433831 | 0.93 | MDM4 (0.54) | SIRT2MDM4TP53MDM2 | |
| SCHEMBL1737899 | 0.93 | MDM4 (0.54) | SIRT2MDM4TP53MDM2 | |
| SCHEMBL12994493 | 0.93 | MDM4 (0.54) | SIRT2MDM4TP53MDM2 | |
| SCHEMBL29399601 | 0.92 | SIRT2 (0.49) | SIRT2MDM4TP53NMBR | |
| SCHEMBL28913050 | 0.92 | SIRT2 (0.49) | SIRT2MDM4TP53NMBR | |
| SCHEMBL28913051 | 0.92 | SIRT2 (0.49) | SIRT2MDM4TP53NMBR | |
| SCHEMBL26556264 | 0.90 | SIRT2 (0.46) | SIRT2MDM4TP53NMBRMDM2 | |
| SCHEMBL17991594 | 0.90 | MDM2 (0.54) | SIRT2MDM4TP53MDM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4656245-A1 | HISTIDINE-BASED UNNATURAL AMINO ACID, ITS PRODUCTION AND USE | PHILIPPS-UNIVERSITÄT MARBURG (DE) | 2025-12-03 | — | — | EP | disclosed |
| EP-4448547-A1 | APELINERGIC MACROCYCLES AND USES THEREOF | Socpra Sciences Santé Et Humaines S.E.C. (CA) | 2024-10-23 | — | — | EP | disclosed |
| US-20240343761-A1 | APELINERGIC MACROCYCLES AND USES THEREOF | SOCPRA SCIENCES SANTÉ ET HUMAINES S.E.C. (CA) | 2024-10-17 | — | — | US | disclosed |
| WO-2023108291-A9 | APELINERGIC MACROCYCLES AND USES THEREOF | SOCPRA SCIENCES SANTÉ ET HUMAINES S.E.C. (CA) | 2023-09-28 | — | — | WO | disclosed |
| WO-2023108291-A1 | APELINERGIC MACROCYCLES AND USES THEREOF | SOCPRA SCIENCES SANTÉ ET HUMAINES S.E.C. (CA) | 2023-06-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240343761-A1 | APELINERGIC MACROCYCLES AND USES THEREOF | APLNR, AP3D1, AP3B1 | SIRT2 2328/4885MDM4 4826/4885TP53 4848/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.