SCHEMBL29368020

SCHEMBL29368020

O=C(N[C@H](Cc1cn(C(c2ccccc2)(c2ccccc2)c2ccccc2)cn1)C(=O)O)OCC1c2ccccc2-c2ccccc21

nearest known ligand 0.59

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ MDM4 O15151 3/20 0.54
▸ TP53 P04637 3/20 0.54
▸ MDM2 Q00987 6/20 0.48
▸ SIRT2 Q8IXJ6 11/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12994493 1.00 MDM4 (0.54) MDM4TP53MDM2SIRT2
SCHEMBL1737899 1.00 MDM4 (0.54) MDM4TP53MDM2SIRT2
SCHEMBL13227674 1.00 MDM4 (0.54) MDM4TP53MDM2SIRT2
SCHEMBL30433831 1.00 MDM4 (0.54) MDM4TP53MDM2SIRT2
SCHEMBL30434660 0.95 MDM2 (0.52) MDM4TP53MDM2SIRT2
SCHEMBL28625947 0.95 MDM2 (0.52) MDM4TP53MDM2SIRT2
SCHEMBL28625949 0.95 MDM2 (0.52) MDM4TP53MDM2SIRT2
SCHEMBL17991594 0.93 MDM2 (0.54) MDM4TP53MDM2SIRT2
SCHEMBL29401153 0.93 MDM2 (0.54) MDM4TP53MDM2SIRT2
SCHEMBL30468161 0.93 SIRT2 (0.55) MDM4TP53MDM2SIRT2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12616761-B2 CXCR4-targeting compounds THE UNIVERSITY OF BRITISH COLUMBIA (CA) 2026-05-05 — — US disclosed
EP-4612314-A2 DNA CATALYST COMPOSITIONS AND METHODS OF DETECTION USING SAME Northern Illinois Research Foundation (US) 2025-09-10 — — EP disclosed
US-20250255975-A1 BICYCLIC PEPTIDE LIGANDS SPECIFIC FOR MT1-MMP Bicyclerd Limited (GB) 2025-08-14 — — US disclosed
US-20250230191-A1 PEPTIDE LIGANDS FOR BINDING TO MT1-MMP BICYCLETX LIMITED (GB) 2025-07-17 — — US disclosed
US-20250213705-A1 PSMA TARGETING LIGANDS AND METHODS OF USE BRIGHT PEAK THERAPEUTICS AG (CH) 2025-07-03 — — US disclosed
US-12318454-B2 Bicyclic peptide ligands specific for MT1-MMP Bicyclerd Limited (GB) 2025-06-03 — — US disclosed
WO-2025041103-A1 PSMA TARGETING LIGANDS AND METHODS OF USE BRIGHT PEAK THERAPEUTICS AG (CH) 2025-02-27 — — WO disclosed
CN-119431497-A Photosensitizer chimera targeting PD-L1 protein and preparation method and application thereof 北京大学 2025-02-14 — — CN disclosed
WO-2025026029-A1 PHOTOSENSITIZER CHIMERA TARGETING PD-L1 PROTEIN, AND PREPARATION METHOD THEREFOR AND USE THEREOF 北京大学 2025-02-06 — — WO disclosed
EP-3452096-B1 BICYCLIC PEPTIDE-TOXIN CONJUGATES SPECIFIC FOR MT1-MMP BICYCLERD LTD (GB) 2025-01-29 — — EP disclosed
US-20220283131-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTES BERTIS CO., LTD. (KR) 2022-09-08 — — US disclosed
CN-114945579-A Heme derivatives, their preparation and use 吉林省澳宇生物科技有限公司 2022-08-26 — — CN disclosed
US-20220229066-A1 COMPOSITIONS, IMAGING, AND THERAPEUTIC METHODS TARGETING FOLATE RECEPTOR 1 (FOLR1) INDI MOLECULAR, INC. 2022-07-21 — — US disclosed
US-20220211648-A1 COMPOSITIONS, DELIVERY SYSTEMS, AND METHODS USEFUL IN TUMOR THERAPY INDI MOLECULAR, INC. 2022-07-07 — — US disclosed
WO-2022107134-A1 EXTREMELY FAST SOLID PHASE SYNTHESIS YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. (IL) 2022-05-27 — — WO disclosed
WO-2022082312-A1 NOVEL CXCR4-TARGETING COMPOUNDS PROVINCIAL HEALTH SERVICES AUTHORITY (CA) 2022-04-28 — — WO disclosed
WO-2022082006-A1 BINDING ASSAYS INVOLVING A PLURALITY OF SYNTHETIC COMPOUNDS, TARGETS, AND COUNTER TARGETS SRI INTERNATIONAL (US) 2022-04-21 — — WO disclosed
WO-2022064052-A1 PEPTIDIC CONJUGATES OF SN38 USEFUL IN THE TREATMENT OF CANCER FUNDACIÓ INSTITUT DE RECERCA BIOMÈDICA (IRB BARCELONA) (ES) 2022-03-31 — — WO disclosed
WO-2022050529-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE ㈜베르티스 2022-03-10 — — WO disclosed
WO-2022026629-A1 CONJUGATED HEPCIDIN MIMETICS PROTAGONIST THERAPEUTICS, INC. (US) 2022-02-03 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220229066-A1 COMPOSITIONS, IMAGING, AND THERAPEUTIC METHODS TARGETING FOLATE RECEPTOR 1 (FOLR1) FOLR1, FOLR2, FOLH1 MDM4 3743/4885TP53 1046/4885MDM2 2259/4885
US-20250230191-A1 PEPTIDE LIGANDS FOR BINDING TO MT1-MMP MMP11, MMP3, ANPEP MDM4 3415/4885TP53 3318/4885MDM2 2867/4885
US-20250255975-A1 BICYCLIC PEPTIDE LIGANDS SPECIFIC FOR MT1-MMP MMEL1, MMP3, TIMP3 MDM4 2089/4885TP53 826/4885MDM2 1933/4885
US-12616761-B2 CXCR4-targeting compounds CXCR4, CXCR2, CXCR3 MDM4 3817/4885TP53 1733/4885MDM2 3597/4885
US-20250213705-A1 PSMA TARGETING LIGANDS AND METHODS OF USE FOLH1, KLK3, PSMA2 MDM4 1652/4885TP53 175/4885MDM2 2036/4885
US-12318454-B2 Bicyclic peptide ligands specific for MT1-MMP MMEL1, MMP3, TIMP3 MDM4 2089/4885TP53 826/4885MDM2 1933/4885
US-20220211648-A1 COMPOSITIONS, DELIVERY SYSTEMS, AND METHODS USEFUL IN TUMOR THERAPY TP53, BAX, RNASE1 MDM4 1793/4885TP53 1/4885MDM2 566/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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