SCHEMBL1737899

SCHEMBL1737899

O=C(N[C@@H](Cc1cn(C(c2ccccc2)(c2ccccc2)c2ccccc2)cn1)C(=O)O)OCC1c2ccccc2-c2ccccc21

nearest known ligand 0.59

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ MDM4 O15151 3/20 0.54
▸ TP53 P04637 3/20 0.54
▸ MDM2 Q00987 6/20 0.48
▸ SIRT2 Q8IXJ6 11/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29368020 1.00 MDM4 (0.54) MDM4TP53MDM2SIRT2
SCHEMBL12994493 1.00 MDM4 (0.54) MDM4TP53MDM2SIRT2
SCHEMBL13227674 1.00 MDM4 (0.54) MDM4TP53MDM2SIRT2
SCHEMBL30433831 1.00 MDM4 (0.54) MDM4TP53MDM2SIRT2
SCHEMBL30434660 0.95 MDM2 (0.52) MDM4TP53MDM2SIRT2
SCHEMBL28625947 0.95 MDM2 (0.52) MDM4TP53MDM2SIRT2
SCHEMBL28625949 0.95 MDM2 (0.52) MDM4TP53MDM2SIRT2
SCHEMBL17991594 0.93 MDM2 (0.54) MDM4TP53MDM2SIRT2
SCHEMBL29401153 0.93 MDM2 (0.54) MDM4TP53MDM2SIRT2
SCHEMBL30468161 0.93 SIRT2 (0.55) MDM4TP53MDM2SIRT2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 816 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250361272-A1 HISTIDINE-BASED UNNATURAL AMINO ACID, ITS PRODUCTION AND USE PHILIPPS-UNIVERSITÄT MARBURG (DE) 2025-11-27 — — US claimed
CN-120114563-A Biotin tripeptide with hair growth function and composition, preparation method and application thereof 天津科技大学 2025-06-10 — — CN claimed
CN-119661691-A N-terminal modified cosmetic polypeptide composition and synthesis method thereof 湖南益安生物科技有限公司 2025-03-21 — — CN claimed
CN-119661633-A Method for full liquid phase synthesis of blue copper peptide 湖南益安生物科技有限公司 2025-03-21 — — CN claimed
CN-119638822-A Full liquid phase synthesis method of oligopeptide-1 湖南益安生物科技有限公司 2025-03-18 — — CN claimed
CN-118994321-B Preparation method and application of cosmetic cyclic peptide reagent 杭州皓阳生物技术有限公司 2025-02-14 — — CN claimed
CN-118948698-B Refreshing oil control composition and preparation process thereof 广州市可颜化妆品有限公司 2025-01-28 — — CN claimed
CN-114249810-B Synthetic method of somalupeptide 深圳翰宇药业股份有限公司 2025-01-24 — — CN claimed
CN-119306796-A Golden-silk-flos chrysanthemi oligopeptide and 9 peptide with blood fat reducing and weight losing effects, and preparation methods and applications thereof 天津科技大学 2025-01-14 — — CN claimed
CN-118994321-A Preparation method and application of cosmetic cyclic peptide reagent 杭州皓阳生物技术有限公司 2024-11-22 — — CN claimed
CN-114487164-A Separation detection method for protected amino acid and impurity with N-terminal removed protecting group 四川汇宇制药股份有限公司 2022-05-13 — — CN claimed
CN-114014912-B Method for preparing leuprorelin by combining solid phase and liquid phase 浙江湃肽生物有限公司南京分公司 2022-03-29 — — CN claimed
CN-113121673-B Method for preparing elcatonin by solid-liquid combination method 润辉生物技术(威海)有限公司 2022-03-29 — — CN claimed
CN-114249810-A Synthetic method of somaglutide 深圳翰宇药业股份有限公司 2022-03-29 — — CN claimed
CN-114249808-A Synthesis method of Cagrilintide 杭州诺泰澳赛诺医药技术开发有限公司 2022-03-29 — — CN claimed
CN-110294800-B Preparation method of somaglutide 齐鲁制药有限公司 2022-03-04 — — CN claimed
CN-114057862-A Synthetic method of GLP-1(1-37) polypeptide 安徽省国平药业有限公司 2022-02-18 — — CN claimed
CN-113880921-B Synthetic method of bremer langdan acetate 浙江湃肽生物有限公司南京分公司 2022-02-18 — — CN claimed
CN-114014912-A Method for preparing leuprorelin by combining solid phase and liquid phase 浙江湃肽生物有限公司南京分公司 2022-02-08 — — CN claimed
CN-113402465-A Preparation method of N-9-fluorenylmethoxycarbonyl-N' -trityl-L-histidine 常州吉恩药业有限公司 2021-09-17 — — CN claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250361272-A1 HISTIDINE-BASED UNNATURAL AMINO ACID, ITS PRODUCTION AND USE H1-0, BCAT1, H1-2 MDM4 1798/4885TP53 2290/4885MDM2 1870/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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