SCHEMBL29400732

SCHEMBL29400732

C=CCOC(=O)NCCC[C@@H](NC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)O

nearest known ligand 0.55

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ KMT2A Q03164 1/20 0.55
▸ MDM2 Q00987 5/20 0.50
▸ TLR2 O60603 2/20 0.49
▸ MDM4 O15151 1/20 0.48
▸ TP53 P04637 1/20 0.48
▸ CASP3 P42574 2/20 0.46
▸ CASP1 P29466 2/20 0.46
▸ TGM2 P21980 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29400312 1.00 KMT2A (0.55) KMT2AMDM2TLR2MDM4TP53
SCHEMBL119653 1.00 KMT2A (0.55) KMT2AMDM2TLR2MDM4TP53
SCHEMBL119648 1.00 KMT2A (0.55) KMT2AMDM2TLR2MDM4TP53
SCHEMBL12898821 1.00 KMT2A (0.55) KMT2AMDM2TLR2MDM4TP53
SCHEMBL178688 1.00 KMT2A (0.55) KMT2AMDM2TLR2MDM4TP53
SCHEMBL25358347 0.97 KMT2A (0.57) KMT2AMDM2TLR2MDM4TP53
SCHEMBL21462054 0.97 KMT2A (0.57) KMT2AMDM2TLR2MDM4TP53
SCHEMBL29401249 0.97 KMT2A (0.57) KMT2AMDM2TLR2MDM4TP53
SCHEMBL178771 0.97 KMT2A (0.57) KMT2AMDM2TLR2MDM4TP53
SCHEMBL29350360 0.97 KMT2A (0.57) KMT2AMDM2TLR2MDM4TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4425181-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE Bertis Inc (KR) 2024-09-04 — — EP disclosed
US-20240011979-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTES BERTIS INC. (KR) 2024-01-11 — — US disclosed
US-11674136-B2 DNA-templated macrocycle library PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2023-06-13 — — US disclosed
WO-2023075435-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE 주식회사 베르티스 2023-05-04 — — WO disclosed
US-20220283131-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTES BERTIS CO., LTD. (KR) 2022-09-08 — — US disclosed
WO-2022050529-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE ㈜베르티스 2022-03-10 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11674136-B2 DNA-templated macrocycle library IDE, IAPP, POLRMT KMT2A 3958/4885MDM2 938/4885TLR2 4684/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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