SCHEMBL29400784

SCHEMBL29400784

CC(C)(C)OC(=O)CC[C@H](NC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)Oc1c(F)c(F)c(F)c(F)c1F

nearest known ligand 0.51

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
MDM2 Q00987 1/20 0.44
MDM4 O15151 2/20 0.43
TP53 P04637 2/20 0.43
TLR2 O60603 2/20 0.42
PTPN1 P18031 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17322761 1.00 MDM2 (0.44) MDM2MDM4TP53TLR2PTPN1
SCHEMBL29400880 1.00 MDM2 (0.44) MDM2MDM4TP53TLR2PTPN1
SCHEMBL25835417 0.94 MDM2 (0.42) MDM2MDM4TP53TLR2PTPN1
SCHEMBL29398411 0.90 CASP3 (0.44) MDM2MDM4TP53
SCHEMBL29401312 0.90 CASP3 (0.44) MDM2MDM4TP53
SCHEMBL29692843 0.90 PTPN1 (0.43) MDM2TLR2PTPN1
SCHEMBL29692939 0.90 PTPN1 (0.53) MDM2PTPN1
SCHEMBL27728772 0.89 MDM4 (0.49) MDM2MDM4TP53TLR2
SCHEMBL14436881 0.88 MDM2 (0.47) MDM2MDM4TP53TLR2
SCHEMBL29706701 0.88 MDM2 (0.45) MDM2MDM4TP53TLR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025094036-A1 A PROCESS FOR THE PREPARATION OF LIRAGLUTIDE PIRAMAL PHARMA LIMITED (IN) 2025-05-08 WO disclosed
EP-4425181-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE Bertis Inc (KR) 2024-09-04 EP disclosed
US-20240175019-A1 Skeletal Muscle Delivery Platforms and Methods of Use Arrowhead Pharmaceuticals, Inc. 2024-05-30 US disclosed
US-20240011979-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTES BERTIS INC. (KR) 2024-01-11 US disclosed
CN-116829949-A Compositions for detecting or measuring analytes 伯蒂斯有限公司 2023-09-29 CN disclosed
US-20230265429-A1 SKELETAL MUSCLE DELIVERY PLATFORMS AND METHODS OF USE THEREOF Arrowhead Pharmaceuticals, Inc. 2023-08-24 US disclosed
CN-116490214-A Skeletal muscle delivery platform and method of use 箭头药业股份有限公司 2023-07-25 CN disclosed
EP-4210763-A1 SKELETAL MUSCLE DELIVERY PLATFORMS AND METHODS OF USE Arrowhead Pharmaceuticals, Inc. (US) 2023-07-19 EP disclosed
EP-4210713-A1 SKELETAL MUSCLE DELIVERY PLATFORMS AND METHODS OF USE Arrowhead Pharmaceuticals, Inc. (US) 2023-07-19 EP disclosed
EP-4210759-A1 LIPID CONJUGATES FOR THE DELIVERY OF THERAPEUTIC AGENTS Arrowhead Pharmaceuticals, Inc. (US) 2023-07-19 EP disclosed
CN-116348150-A Lipid conjugates for delivery of therapeutic agents 箭头药业股份有限公司 2023-06-27 CN disclosed
WO-2023075435-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE 주식회사 베르티스 2023-05-04 WO disclosed
US-20220283131-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTES BERTIS CO., LTD. (KR) 2022-09-08 US disclosed
WO-2022056277-A1 SKELETAL MUSCLE DELIVERY PLATFORMS AND METHODS OF USE Arrowhead Pharmaceuticals, Inc. (US) 2022-03-17 WO disclosed
WO-2022056269-A1 SKELETAL MUSCLE DELIVERY PLATFORMS AND METHODS OF USE Arrowhead Pharmaceuticals, Inc. (US) 2022-03-17 WO disclosed
WO-2022056273-A1 LIPID CONJUGATES FOR THE DELIVERY OF THERAPEUTIC AGENTS Arrowhead Pharmaceuticals, Inc. (US) 2022-03-17 WO disclosed
WO-2022050529-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE ㈜베르티스 2022-03-10 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240175019-A1 Skeletal Muscle Delivery Platforms and Methods of Use MUSK, MYLK2, ITGB6 MDM2 3466/4885MDM4 4404/4885TP53 4158/4885
US-20230265429-A1 SKELETAL MUSCLE DELIVERY PLATFORMS AND METHODS OF USE THEREOF MUSK, MYLK2, TNNC1 MDM2 3780/4885MDM4 4563/4885TP53 4218/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.