Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | CASP6 | P55212 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | TTR | P02766 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
| ▸ | XDH | P47989 | 1/20 | 0.31 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21437229 | 1.00 | ACHE (0.37) | ACHEPARP1MEN1MAOAMAOB | |
| SCHEMBL18508720 | 0.83 | TRPA1 (0.44) | CYP2A6MAPTXDHSLC22A12CNR2 | |
| SCHEMBL23616677 | 0.79 | S1PR4 (0.39) | ACHEPARP1CYP2A6PTGS1 | |
| SCHEMBL21438322 | 0.79 | PARP1 (0.36) | ACHEPARP1CYP2A6CA2PTGS1 | |
| SCHEMBL15018796 | 0.75 | NQO2 (0.40) | MEN1KMT2ACYP2A6KDM4ECA2 | |
| SCHEMBL22607007 | 0.75 | PDE4A (0.38) | MEN1KMT2ACA2MAPT | |
| SCHEMBL30395946 | 0.75 | PDE4A (0.38) | MEN1KMT2ACA2MAPT | |
| SCHEMBL4847264 | 0.74 | CA9 (0.38) | MEN1KMT2ACYP2A6KDM4EALDH1A1 | |
| SCHEMBL22607042 | 0.72 | SELL (0.41) | ACHEMEN1MAOAMAOBEPHX2 | |
| SCHEMBL5559032 | 0.72 | NSD1 (0.34) | MAOAMAOBKDM4EMAPTXDH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111225907-B | Process for preparing benzothien-2 yl boric acid/borate | 拜耳制药股份公司 | 2023-05-26 | — | — | CN | disclosed |
| US-20220356194-A1 | PROCESS FOR PREPARING BENZOTHIOPHEN-2YL BORONATE | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2022-11-10 | — | — | US | disclosed |
| US-11274110-B2 | Process for preparing benzothiophen-2yl boronate | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2022-03-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220356194-A1 | PROCESS FOR PREPARING BENZOTHIOPHEN-2YL BORONATE | BPGM, BRCA1, BRAP | ACHE 4734/4885PARP1 1363/4885MEN1 144/4885 |
| US-11274110-B2 | Process for preparing benzothiophen-2yl boronate | BPGM, BRCA1, BRAP | ACHE 4734/4885PARP1 1363/4885MEN1 144/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.