SCHEMBL29401153

SCHEMBL29401153

COc1ccc(C(c2ccccc2)(c2ccccc2)n2cnc(C[C@H](NC(=O)OCC3c4ccccc4-c4ccccc43)C(=O)O)c2)cc1

nearest known ligand 0.54

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ MDM2 Q00987 5/20 0.54
▸ MDM4 O15151 3/20 0.53
▸ TP53 P04637 3/20 0.53
▸ SIRT2 Q8IXJ6 12/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17991594 1.00 MDM2 (0.54) MDM2MDM4TP53SIRT2
SCHEMBL1737899 0.93 MDM4 (0.54) MDM2MDM4TP53SIRT2
SCHEMBL13227674 0.93 MDM4 (0.54) MDM2MDM4TP53SIRT2
SCHEMBL12994493 0.93 MDM4 (0.54) MDM2MDM4TP53SIRT2
SCHEMBL29368020 0.93 MDM4 (0.54) MDM2MDM4TP53SIRT2
SCHEMBL30433831 0.93 MDM4 (0.54) MDM2MDM4TP53SIRT2
SCHEMBL28625949 0.92 MDM2 (0.52) MDM2MDM4TP53SIRT2
SCHEMBL28625947 0.92 MDM2 (0.52) MDM2MDM4TP53SIRT2
SCHEMBL30434660 0.92 MDM2 (0.52) MDM2MDM4TP53SIRT2
SCHEMBL30468161 0.90 SIRT2 (0.55) MDM2MDM4TP53SIRT2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12415835-B2 Peptide-compound cyclization method CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2025-09-16 — — US disclosed
US-12227542-B2 Method for producing peptide compound, protective group-forming reagent, and condensed polycyclic compound FUJIFILM CORPORATION (JP) 2025-02-18 — — US disclosed
EP-4425181-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE Bertis Inc (KR) 2024-09-04 — — EP disclosed
US-11891457-B2 Peptide-compound cyclization method CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2024-02-06 — — US disclosed
US-20240011979-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTES BERTIS INC. (KR) 2024-01-11 — — US disclosed
CN-110922452-B Method for synthesizing goserelin 深圳翰宇药业股份有限公司 2023-12-26 — — CN disclosed
CN-110922453-B Method for synthesizing goserelin 深圳翰宇药业股份有限公司 2023-12-26 — — CN disclosed
CN-116829949-A Compositions for detecting or measuring analytes 伯蒂斯有限公司 2023-09-29 — — CN disclosed
WO-2023075435-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE 주식회사 베르티스 2023-05-04 — — WO disclosed
US-20220283131-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTES BERTIS CO., LTD. (KR) 2022-09-08 — — US disclosed
EP-3992187-A1 METHOD FOR PRODUCING PEPTIDE COMPOUND, REAGENT FOR FORMING PROTECTIVE GROUP, AND FUSED POLYCYCLIC COMPOUND FUJIFILM Corporation (JP) 2022-05-04 — — EP disclosed
US-20220112234-A1 METHOD FOR PRODUCING PEPTIDE COMPOUND, PROTECTIVE GROUP-FORMING REAGENT, AND CONDENSED POLYCYCLIC COMPOUND FUJIFILM CORPORATION (JP) 2022-04-14 — — US disclosed
EP-3974563-A1 CYCLIC PEPTIDES Chugai Seiyaku Kabushiki Kaisha (JP) 2022-03-30 — — EP disclosed
WO-2022050529-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE ㈜베르티스 2022-03-10 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12227542-B2 Method for producing peptide compound, protective group-forming reagent, and condensed polycyclic compound C9, GRPR, VIP MDM2 1622/4885MDM4 3663/4885TP53 2041/4885
US-11891457-B2 Peptide-compound cyclization method VIP, NGLY1, GLP1R MDM2 2401/4885MDM4 3559/4885TP53 2654/4885
US-20220112234-A1 METHOD FOR PRODUCING PEPTIDE COMPOUND, PROTECTIVE GROUP-FORMING REAGENT, AND CONDENSED POLYCYCLIC COMPOUND C9, GRPR, VIP MDM2 1622/4885MDM4 3663/4885TP53 2041/4885
US-12415835-B2 Peptide-compound cyclization method VIP, NGLY1, GLP1R MDM2 2401/4885MDM4 3559/4885TP53 2654/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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