SCHEMBL29401455

SCHEMBL29401455

C[C@H](OC(C)(C)C)[C@H](NC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)O

nearest known ligand 0.52

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CASP3 P42574 4/20 0.50
MDM4 O15151 2/20 0.48
TP53 P04637 2/20 0.48
PIN1 Q13526 1/20 0.47
KMT2A Q03164 2/20 0.46
EPHX2 P34913 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30477937 1.00 CASP3 (0.50) CASP3MDM4TP53PIN1KMT2A
SCHEMBL29398070 1.00 CASP3 (0.50) CASP3MDM4TP53PIN1KMT2A
SCHEMBL30252212 1.00 CASP3 (0.50) CASP3MDM4TP53PIN1KMT2A
SCHEMBL119402 1.00 CASP3 (0.50) CASP3MDM4TP53PIN1KMT2A
SCHEMBL2366569 1.00 CASP3 (0.50) CASP3MDM4TP53PIN1KMT2A
SCHEMBL2366563 1.00 CASP3 (0.50) CASP3MDM4TP53PIN1KMT2A
SCHEMBL1738651 1.00 CASP3 (0.50) CASP3MDM4TP53PIN1KMT2A
SCHEMBL31575313 1.00 CASP3 (0.50) CASP3MDM4TP53PIN1KMT2A
SCHEMBL2367241 1.00 CASP3 (0.50) CASP3MDM4TP53PIN1KMT2A
SCHEMBL12055781 1.00 CASP3 (0.50) CASP3MDM4TP53PIN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4748847-A1 PEPTIDE COMPLEX HAVING VEGFR -2 AGONIST ACTIVITY Peptidream Inc (JP) 2026-05-27 EP disclosed
US-20260022142-A1 MACROCYCLIC IMMUNOMODULATORS BRISTOL MYERS SQUIBB CO (US) 2026-01-22 US disclosed
EP-3966226-B1 MASP INHIBITORY COMPOUNDS AND USES THEREOF BAYER AG (DE) 2025-12-24 EP disclosed
US-12503491-B2 MASP inhibitory compounds and uses thereof BAYER AKTIENGESELLSCHAFT (DE) 2025-12-23 US disclosed
US-20250332300-A1 HER2 TARGETING CYCLIC PEPTIDES AND CONJUGATES THEREOF NOVARTIS AG (CH) 2025-10-30 US disclosed
CN-119936214-A Detection method of atosiban key isomer 四川科伦药物研究院有限公司 2025-05-06 CN disclosed
EP-4526323-A1 MACROCYCLIC IMMUNOMODULATORS Bristol-Myers Squibb Company (US) 2025-03-26 EP disclosed
EP-4425181-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE Bertis Inc (KR) 2024-09-04 EP disclosed
EP-4387980-A1 INHIBITORS OF CYSTEINE PROTEASES AND METHODS OF USE THEREOF Pardes Biosciences, Inc. (US) 2024-06-26 EP disclosed
US-20240124522-A1 MASP INHIBITORY COMPOUNDS AND USES THEREOF BAYER AKTIENGESELLSCHAFT (DE) 2024-04-18 US disclosed
US-20240011979-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTES BERTIS INC. (KR) 2024-01-11 US disclosed
WO-2023225661-A1 MACROCYCLIC IMMUNOMODULATORS BRISTOL-MYERS SQUIBB COMPANY (US) 2023-11-23 WO disclosed
CN-116829949-A Compositions for detecting or measuring analytes 伯蒂斯有限公司 2023-09-29 CN disclosed
CN-116577443-A Method for separating and detecting amino acid derivative and related impurities thereof 成都郑源生化科技有限公司 2023-08-11 CN disclosed
US-11667675-B2 MASP inhibitory compounds and uses thereof BAYER AKTIENGESELLSCHAFT (DE) 2023-06-06 US disclosed
WO-2023075435-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE 주식회사 베르티스 2023-05-04 WO disclosed
WO-2023023631-A1 INHIBITORS OF CYSTEINE PROTEASES AND METHODS OF USE THEREOF Pardes Biosciences, Inc. (US) 2023-02-23 WO disclosed
US-20220283131-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTES BERTIS CO., LTD. (KR) 2022-09-08 US disclosed
WO-2022050529-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE ㈜베르티스 2022-03-10 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12503491-B2 MASP inhibitory compounds and uses thereof MASP2, SERPINB1, SPINT2 CASP3 795/4885MDM4 2629/4885TP53 2648/4885
US-20260022142-A1 MACROCYCLIC IMMUNOMODULATORS CD274, PDCD1LG2, PDCD1 CASP3 1560/4885MDM4 3040/4885TP53 421/4885
US-11667675-B2 MASP inhibitory compounds and uses thereof MASP2, SERPINB1, SPINT2 CASP3 795/4885MDM4 2629/4885TP53 2648/4885
US-20240124522-A1 MASP INHIBITORY COMPOUNDS AND USES THEREOF MASP2, SERPINB1, SPINT2 CASP3 795/4885MDM4 2629/4885TP53 2648/4885
US-20250332300-A1 HER2 TARGETING CYCLIC PEPTIDES AND CONJUGATES THEREOF ERBB2, EGFR, ERBB3 CASP3 1904/4885MDM4 2510/4885TP53 112/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.