SCHEMBL2940168

SCHEMBL2940168

Nc1cc(I)c(S(N)(=O)=O)cc1S(N)(=O)=O

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 12/20 0.57
CA1 P00915 11/20 0.57
CA9 Q16790 10/20 0.57
CA4 P22748 6/20 0.57
CA12 O43570 6/20 0.57
CA6 P23280 5/20 0.57
CA5A P35218 5/20 0.57
CA7 P43166 5/20 0.57
CA14 Q9ULX7 5/20 0.57
CA5B Q9Y2D0 5/20 0.57
CA3 P07451 2/20 0.57
ALDH1A1 P00352 3/20 0.48
APEX1 P27695 2/20 0.41
CYP2C9 P11712 1/20 0.41
CYP2C19 P33261 1/20 0.41
KDM4E B2RXH2 1/20 0.40
PKM P14618 1/20 0.38
POLB P06746 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27699058 0.88 CA1 (0.50) CA2CA1CA9CA4CA12
SCHEMBL27699059 0.88 CA1 (0.46) CA2CA1CA9CA4CA12
SCHEMBL3777946 0.86 CA1 (0.50) CA2CA1CA9CA4CA12
SCHEMBL3772813 0.82 CA1 (0.50) CA2CA1CA9CA4CA12
SCHEMBL17774552 0.80 CA2 (0.65) CA2CA1CA9CA4CA12
SCHEMBL5624037 0.77 CA1 (0.47) CA2CA1CA9CA4CA12
SCHEMBL9646596 0.74 CA2 (0.59) CA2CA1CA9CA4CA12
SCHEMBL3773170 0.73 KDM4E (0.45) CA2CA1CA9CA4CA12
SCHEMBL30659050 0.73 CA1 (1.00) CA2CA1CA9CA4CA12
SCHEMBL20150025 0.73 CA1 (0.47) CA2CA1CA9CA4CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1717228-A1 Sulfonylamino(thio)carbonylderivatives as herbicides or plant growth regulators Bayer CropScience GmbH (DE) 2006-11-02 EP claimed
US-20120004363-A1 REINFORCED POLYESTER RESIN COMPOSITION ADEKA CORPORATION (JP) 2012-01-05 US disclosed
US-7855166-B2 Sulfonylamino(thio)carbonyl compounds BAYER CROPSCIENCE GMBH (DE) 2010-12-21 US disclosed
US-20100113710-A1 POLYESTER RESIN COMPOSITION ADEKA CORPORATION (JP) 2010-05-06 US disclosed
EP-2077298-A1 POLYESTER RESIN COMPOSITION Adeka Corporation (JP) 2009-07-08 EP disclosed
CN-101166724-A Sulfonylamino (thio) carbonyl compounds in the form of herbicides or plant growth regulators BAYER CROPSCIENCE AG (DE) 2008-04-23 CN disclosed
US-20060258536-A1 Sulfonylamino(thio)carbonyl compounds BAYER CROPSCIENCE GMBH (DE) 2006-11-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060258536-A1 Sulfonylamino(thio)carbonyl compounds TST, CBR3, MYB CA2 3775/4885CA1 4582/4885CA9 3837/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.