SCHEMBL29401707

SCHEMBL29401707

CC(C)(C)OC(=O)N[C@H](CCCCNC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)O

nearest known ligand 0.69

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 0.58
MDM2 Q00987 6/20 0.57
TLR2 O60603 3/20 0.56
TLR1 Q15399 1/20 0.56
KLK7 P49862 1/20 0.49
KLK5 Q9Y337 1/20 0.49
ALDH1A1 P00352 1/20 0.49
TSHR P16473 1/20 0.49
MDM4 O15151 1/20 0.48
TP53 P04637 1/20 0.48
MAPT P10636 1/20 0.48
IDO1 P14902 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29362262 1.00 KMT2A (0.58) KMT2AMDM2TLR2TLR1KLK7
SCHEMBL2267346 1.00 KMT2A (0.58) KMT2AMDM2TLR2TLR1KLK7
SCHEMBL30885878 1.00 KMT2A (0.58) KMT2AMDM2TLR2TLR1KLK7
SCHEMBL999302 1.00 KMT2A (0.58) KMT2AMDM2TLR2TLR1KLK7
SCHEMBL12040103 1.00 KMT2A (0.58) KMT2AMDM2TLR2TLR1KLK7
SCHEMBL1000135 0.99 KMT2A (0.60) KMT2AMDM2TLR2TLR1KLK7
SCHEMBL7392221 0.97 MDM2 (0.57) KMT2AMDM2TLR2TLR1KLK7
SCHEMBL7815145 0.97 MDM2 (0.57) KMT2AMDM2TLR2TLR1KLK7
SCHEMBL17669898 0.97 MDM2 (0.57) KMT2AMDM2TLR2TLR1KLK7
SCHEMBL30441695 0.97 MDM2 (0.57) KMT2AMDM2TLR2TLR1KLK7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4663205-A1 POLYMER-DRUG CONJUGATE, INTERMEDIATE THEREOF, AND USE THEREOF Shanghai Best-Link Bioscience, LLC (CN) 2025-12-17 EP disclosed
US-20250130235-A1 PHOSPHORYLATED AKT-SPECIFIC CAPTURE AGENTS, COMPOSITIONS, AND METHODS OF USING AND MAKING CALIFORNIA INSTITUTE OF TECHNOLOGY 2025-04-24 US disclosed
EP-4466069-A1 GLP-1/GIP RECEPTOR CO-AGONIST PRODRUGS AND USES THEREOF Novo Nordisk A/S (DK) 2024-11-27 EP disclosed
WO-2024222960-A1 POLYMER-DRUG CONJUGATE, INTERMEDIATE THEREOF, AND USE THEREOF 上海弼领生物技术有限公司 2024-10-31 WO disclosed
WO-2024184332-A1 TRACEABLE CHIMERIC ANTIGEN RECEPTOR CELL EBERHARD KARLS UNIVERSITAET TUEBINGEN MEDIZINISCHE FAKULTAET (DE) 2024-09-12 WO disclosed
EP-4427759-A1 TRACEABLE CHIMERIC ANTIGEN RECEPTOR CELL Eberhard-Karls-Universität Tübingen (DE) 2024-09-11 EP disclosed
CN-118632867-A GLP-1/GIP receptor co-agonist prodrugs and uses thereof 诺和诺德股份有限公司 2024-09-10 CN disclosed
EP-4425181-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE Bertis Inc (KR) 2024-09-04 EP disclosed
CN-112915210-B Polyethylene glycol coupling drug, preparation method and application thereof 重庆阿普格雷生物科技有限公司 2024-08-20 CN disclosed
CN-113995847-B Polyethylene glycol coupling medicine, preparation method and application thereof 重庆阿普格雷生物科技有限公司 2024-06-25 CN disclosed
US-20230073036-A1 POLYETHYLENE GLYCOL CONJUGATE DRUG, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF Chongqing Upgra Biotechnology Co., Ltd. (CN) 2023-03-09 US disclosed
CN-115697380-A PTH analogs for treatment of hypoparathyroidism 印第安纳大学研究与技术公司 2023-02-03 CN disclosed
US-20230019342-A1 PHOSPHORYLATED AKT-SPECIFIC CAPTURE AGENTS, COMPOSITIONS, AND METHODS OF USING AND MAKING CALIFORNIA INSTITUTE OF TECHNOLOGY 2023-01-19 US disclosed
EP-3197912-B1 LIPIDATED AMIDE-BASED INSULIN PRODRUGS UNIV INDIANA RES & TECH CORP (US) 2023-01-04 EP disclosed
EP-4070820-A1 POLYETHYLENE GLYCOL CONJUGATE DRUG, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF Chongqing Upgra Biotechnology Co., Ltd. (CN) 2022-10-12 EP disclosed
EP-4066861-A1 POLYETHYLENE GLYCOL CONJUGATE MEDICAMENT, PREPARATION METHOD THERFOR AND USE THEREOF Chongqing Upgra Biotechnology Co., Ltd. (CN) 2022-10-05 EP disclosed
EP-4066860-A1 POLYETHYLENE GLYCOL CONJUGATED DRUG, AND PREPARATION METHOD THEREFOR AND USE THEREOF Chongqing Upgra Biotechnology Co., Ltd. (CN) 2022-10-05 EP disclosed
US-20220283131-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTES BERTIS CO., LTD. (KR) 2022-09-08 US disclosed
US-11371994-B2 Phosphorylated Akt-specific capture agents, compositions, and methods of using and making CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2022-06-28 US disclosed
WO-2022050529-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE ㈜베르티스 2022-03-10 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11371994-B2 Phosphorylated Akt-specific capture agents, compositions, and methods of using and making PIK3CA, PIK3CB, AKT3 KMT2A 1771/4885MDM2 2307/4885TLR2 3238/4885
US-20230073036-A1 POLYETHYLENE GLYCOL CONJUGATE DRUG, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF SLC10A1, FAR1, THEM6 KMT2A 3642/4885MDM2 3177/4885TLR2 2760/4885
US-20250130235-A1 PHOSPHORYLATED AKT-SPECIFIC CAPTURE AGENTS, COMPOSITIONS, AND METHODS OF USING AND MAKING PIK3CA, PIK3CB, AKT3 KMT2A 1771/4885MDM2 2307/4885TLR2 3238/4885
US-20230019342-A1 PHOSPHORYLATED AKT-SPECIFIC CAPTURE AGENTS, COMPOSITIONS, AND METHODS OF USING AND MAKING PIK3CA, PIK3CB, AKT3 KMT2A 1771/4885MDM2 2307/4885TLR2 3238/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.