SCHEMBL2267346

SCHEMBL2267346

CC(C)(C)OC(=O)NC(CCCCNC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)O

nearest known ligand 0.69

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 0.58
MDM2 Q00987 6/20 0.57
TLR2 O60603 3/20 0.56
TLR1 Q15399 1/20 0.56
KLK7 P49862 1/20 0.49
KLK5 Q9Y337 1/20 0.49
ALDH1A1 P00352 1/20 0.49
TSHR P16473 1/20 0.49
MDM4 O15151 1/20 0.48
TP53 P04637 1/20 0.48
MAPT P10636 1/20 0.48
IDO1 P14902 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29362262 1.00 KMT2A (0.58) KMT2AMDM2TLR2TLR1KLK7
SCHEMBL29401707 1.00 KMT2A (0.58) KMT2AMDM2TLR2TLR1KLK7
SCHEMBL30885878 1.00 KMT2A (0.58) KMT2AMDM2TLR2TLR1KLK7
SCHEMBL999302 1.00 KMT2A (0.58) KMT2AMDM2TLR2TLR1KLK7
SCHEMBL12040103 1.00 KMT2A (0.58) KMT2AMDM2TLR2TLR1KLK7
SCHEMBL1000135 0.99 KMT2A (0.60) KMT2AMDM2TLR2TLR1KLK7
SCHEMBL7392221 0.97 MDM2 (0.57) KMT2AMDM2TLR2TLR1KLK7
SCHEMBL7815145 0.97 MDM2 (0.57) KMT2AMDM2TLR2TLR1KLK7
SCHEMBL17669898 0.97 MDM2 (0.57) KMT2AMDM2TLR2TLR1KLK7
SCHEMBL30441695 0.97 MDM2 (0.57) KMT2AMDM2TLR2TLR1KLK7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 127 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111420053-B Multifunctional magnetic nanoparticle compound capable of intracellular aggregation and preparation method thereof 珠海市人民医院 2022-09-09 CN claimed
CN-111420053-A Multifunctional magnetic nanoparticle compound capable of intracellular aggregation and preparation method thereof 珠海市人民医院 2020-07-17 CN claimed
US-20260061065-A1 ANTIBODY DRUG CONJUGATES NOVARTIS AG (CH) 2026-03-05 US disclosed
US-20260007787-A1 RADIOPHARMACEUTICAL SMALL MOLECULE INHIBITORS OF FIBROBLAST ACTIVATION PROTEIN FOR TARGETED THERAPY AND DIAGNOSTIC IMAGING OF DESMOPLASTIC TUMORS TRUSTEES OF TUFTS COLLEGE 2026-01-08 US disclosed
US-20250387504-A1 ANTIBODY-DRUG CONJUGATES OF ANTINEOPLASTIC COMPOUNDS AND METHODS OF USE THEREOF NOVARTIS AG (CH) 2025-12-25 US disclosed
US-12383560-B2 Compounds and uses thereof FOGHORN THERAPEUTICS INC. (US) 2025-08-12 US disclosed
US-20250213685-A1 ANTI-EGFR ANTIBODY DRUG CONJUGATES ABBVIE INC (US) 2025-07-03 US disclosed
US-20250195683-A1 ANTIBODY-DRUG CONJUGATE, PHARMACEUTICAL COMPOSITION THEREOF AND USE THEROF SICHUAN KELUN-BIOTECH BIOPHARMACEUTICAL CO., LTD. (CN) 2025-06-19 US disclosed
US-20250177374-A1 BCL-XL Inhibitory Compounds Having Low Cell Permeability and Antibody Drug Conjugates Including the Same ABBVIE INC (US) 2025-06-05 US disclosed
WO-2025111431-A1 ANTI-CD7 ANTIBODY-DRUG CONJUGATES AND METHODS OF USE THEREOF LES LABORATOIRES SERVIER (FR) 2025-05-30 WO disclosed
US-20250115561-A1 BIPHENYL-SUBSTITUTED EPITHELIAL SODIUM CHANNEL BLOCKING COMPOUNDS PARION SCIENCES, INC. (US) 2025-04-10 US disclosed
WO-2008080223-A1 COMPOSITIONS AND METHODS FOR TREATING HYPERPROLIFERATIVE DISEASE MIGENIX INC. (CA) 2008-07-10 WO disclosed
EP-1910279-A2 NON-NUCLEOSIDE ANTI-HEPACIVIRUS AGENTS AND USES THEREOF MIGENIX INC. (CA) 2008-04-16 EP disclosed
WO-2008031091-A2 A SURFACE-BASED AMMONIUM ION SENSOR: AN ELECTRODE DERIVATIZED WITH A SELF-ASSEMBLED MONOLAYER WORCESTER POLYTECHNIC INSTITUTE (US) 2008-03-13 WO disclosed
US-20070185128-A1 Compounds and compositions for treating obesity NOVO NORDISK A/S (DK) 2007-08-09 US disclosed
EP-1773348-A2 TETRAPEPTIDE ANALOGS Idun Pharmaceuticals, Inc. (US) 2007-04-18 EP disclosed
EP-1518862-B1 Solid phase native chemical ligation of unprotected or n-terminal cysteine protected peptides in aqueous solution GRYPHON THERAPEUTICS INC (US) 2007-02-21 EP disclosed
US-20070021434-A1 NON-NUCLEOSIDE ANTI-HEPACIVIRUS AGENTS AND USES THEREOF MIGENIX INC. (CA) 2007-01-25 US disclosed
WO-2007002639-A2 NON-NUCLEOSIDE ANTI-HEPACIVIRUS AGENTS AND USES THEREOF MIGENIX INC. (CA) 2007-01-04 WO disclosed
WO-2006017295-A2 TETRAPEPTIDE ANALOGS IDUN PHARMACEUTICALS, INC. (US) 2006-02-16 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250115561-A1 BIPHENYL-SUBSTITUTED EPITHELIAL SODIUM CHANNEL BLOCKING COMPOUNDS CFTR, SCNN1B, SCNN1G KMT2A 3783/4885MDM2 4448/4885TLR2 2454/4885
US-20250195683-A1 ANTIBODY-DRUG CONJUGATE, PHARMACEUTICAL COMPOSITION THEREOF AND USE THEROF CD47, ABCB1, EGFR KMT2A 2537/4885MDM2 2059/4885TLR2 2732/4885
US-20260007787-A1 RADIOPHARMACEUTICAL SMALL MOLECULE INHIBITORS OF FIBROBLAST ACTIVATION PROTEIN FOR TARGETED THERAPY AND DIAGNOSTIC IMAGING OF DESMOPLASTIC TUMORS FIBP, FRS2, FGFR1 KMT2A 3715/4885MDM2 1169/4885TLR2 4438/4885
US-20250213685-A1 ANTI-EGFR ANTIBODY DRUG CONJUGATES EGFR, ERBB2, ERBB3 KMT2A 1606/4885MDM2 2085/4885TLR2 3185/4885
US-20070185128-A1 Compounds and compositions for treating obesity MC4R, MC5R, MC3R KMT2A 2554/4885MDM2 4773/4885TLR2 1056/4885
US-20070021434-A1 NON-NUCLEOSIDE ANTI-HEPACIVIRUS AGENTS AND USES THEREOF HAVCR2, ADAR, NSUN2 KMT2A 3406/4885MDM2 3730/4885TLR2 2757/4885
US-20250387504-A1 ANTIBODY-DRUG CONJUGATES OF ANTINEOPLASTIC COMPOUNDS AND METHODS OF USE THEREOF BID, BCL2, MCL1 KMT2A 719/4885MDM2 384/4885TLR2 4179/4885
US-12383560-B2 Compounds and uses thereof VHL, CLN6, TFEB KMT2A 792/4885MDM2 2551/4885TLR2 4839/4885
US-20260061065-A1 ANTIBODY DRUG CONJUGATES FCGR2A, FCGR3B, BCL3 KMT2A 2434/4885MDM2 3219/4885TLR2 1153/4885
US-20250177374-A1 BCL-XL Inhibitory Compounds Having Low Cell Permeability and Antibody Drug Conjugates Including the Same BCL2, BAX, BCL9 KMT2A 2470/4885MDM2 1260/4885TLR2 4736/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.