SCHEMBL294031

SCHEMBL294031

[O]S(=O)(=O)Cc1ccc2ccccc2c1

nearest known ligand 0.52

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.52
CYP2A6 P11509 1/20 0.52
HTR2A P28223 1/20 0.44
HTR2C P28335 1/20 0.44
HTR2B P41595 1/20 0.44
TEAD4 Q15561 1/20 0.44
LMNA P02545 1/20 0.44
MLNR O43193 1/20 0.43
CA1 P00915 4/20 0.43
CA2 P00918 4/20 0.43
CA12 O43570 2/20 0.43
CA4 P22748 2/20 0.43
CA9 Q16790 3/20 0.42
CA7 P43166 2/20 0.42
SIGMAR1 Q99720 1/20 0.42
MC4R P32245 1/20 0.42
MC5R P33032 1/20 0.42
KMT2A Q03164 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27450675 0.85 CYP1A2 (0.54) CYP1A2CYP2A6HTR2AHTR2CHTR2B
SCHEMBL31307180 0.82 CYP1A2 (0.50) CYP1A2CYP2A6HTR2AHTR2CHTR2B
SCHEMBL2374771 0.82 CYP1A2 (0.50) CYP1A2CYP2A6HTR2AHTR2CHTR2B
Menaphthyl Sulfonate SCHEMBL294032 0.82 CYP1A2 (0.50) CYP1A2CYP2A6HTR2AHTR2CHTR2B
SCHEMBL171848 0.82 CYP1A2 (0.55) CYP1A2CYP2A6HTR2AHTR2CHTR2B
SCHEMBL12230567 0.82 CYP1A2 (0.50) CYP1A2CYP2A6HTR2AHTR2CHTR2B
SCHEMBL1764709 0.82 CA1 (0.57) CYP1A2CYP2A6HTR2AHTR2CHTR2B
SCHEMBL6733983 0.82 CYP1A2 (0.50) CYP1A2CYP2A6HTR2AHTR2CHTR2B
SCHEMBL12303235 0.80 CYP1A2 (0.59) CYP1A2CYP2A6HTR2AHTR2CHTR2B
Menaphthyl Sulfonate SCHEMBL6980474 0.80 CYP1A2 (0.48) CYP1A2CYP2A6HTR2AHTR2CHTR2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 148 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4400492-A1 ACRIDINE COMPOUND OSAKA UNIVERSITY (JP) 2024-07-17 EP disclosed
US-20240208999-A1 HETEROCYCLIC COMPOUND OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2024-06-27 US disclosed
CN-118103359-A Preparation method of eribulin derivative 江苏恒瑞医药股份有限公司 2024-05-28 CN disclosed
EP-4370507-A1 HYDROGENATED QUINOXALINES Otsuka Pharmaceutical Co., Ltd. (JP) 2024-05-22 EP disclosed
US-20240148699-A1 OXAZOLE COMPOUND AND PHARMACEUTICAL COMPOSITION OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2024-05-09 US disclosed
CN-117940408-A Acridine compounds 国立大学法人大阪大学 2024-04-26 CN disclosed
US-20240132518-A1 CEPHALOSPORIN ANTIBACTERIAL COMPOUND AND PREPARATION METHOD THEREFOR SHANGHAI SENHUI MEDICINE CO., LTD. (CN) 2024-04-25 US disclosed
EP-4347597-A1 PYRAZOLO[1,5-A]PYRIMIDINE COMPOUND FOR THE TREATMENT OF DERMAL DISORDERS Otsuka Pharmaceutical Co., Ltd. (JP) 2024-04-10 EP disclosed
US-20240109842-A1 ACRYLAMIDE COMPOUNDS OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2024-04-04 US disclosed
US-11932657-B2 Heterocyclic compound OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2024-03-19 US disclosed
US-20090221586-A1 OXAZOLE COMPOUND AND PHARMACEUTICAL COMPOSITION OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2009-09-03 US disclosed
WO-2008150029-A1 QUINOLONE COMPOUND AND PHARMACEUTICAL COMPOSITION OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2008-12-11 WO disclosed
EP-1919907-A2 HETEROCYCLIC COMPOUND OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2008-05-14 EP disclosed
EP-1869025-A1 PIPERAZINE-SUBSTITUTED BENZOTHIOPHENES FOR TREATMENT OF MENTAL DISORDERS OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2007-12-26 EP disclosed
WO-2007026959-A2 DERIVATIVES OF 4-PIPERAZIN-1-YL-4-BENZ0 [B] THIOPHENE SUITABLE FOR THE TREATMENT OF CNS DISORDERS OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2007-03-08 WO disclosed
WO-2006112464-A1 PIPERAZINE-SUBSTITUTED BENZOTHIOPHENES FOR TREATMENT OF MENTAL DISORDERS OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2006-10-26 WO disclosed
CN-1052224-C Peripheral Vasodilating agent containing N-acylated 4-amino piperidine derivatives as active ingredients OTSUKA PHARMA CO LTD (JP) 2000-05-10 CN disclosed
US-4536391-A REACTING A PLASMIN HEAVY CHAIN WITH UROKINASE IN THE PRESENCE OF A COUPLING AGENT OTSUKA PHARMACEUTICAL CO. (JP) 1985-08-20 US disclosed
EP-0109653-A2 Process for preparing urokinase complex OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1984-05-30 EP disclosed
US-4435404-A ANTICOAGULANTS OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1984-03-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240132518-A1 CEPHALOSPORIN ANTIBACTERIAL COMPOUND AND PREPARATION METHOD THEREFOR WASF2, MRPL21, CLSPN CYP1A2 1800/4885CYP2A6 438/4885HTR2A 4447/4885
US-20240148699-A1 OXAZOLE COMPOUND AND PHARMACEUTICAL COMPOSITION PDE3B, PDE4A, PDE3A CYP1A2 35/4885CYP2A6 219/4885HTR2A 2210/4885
US-20090221586-A1 OXAZOLE COMPOUND AND PHARMACEUTICAL COMPOSITION PDE3B, PDE4A, PDE3A CYP1A2 35/4885CYP2A6 219/4885HTR2A 2210/4885
US-20240109842-A1 ACRYLAMIDE COMPOUNDS HPGDS, MYADM, ACR CYP1A2 888/4885CYP2A6 687/4885HTR2A 750/4885
US-11932657-B2 Heterocyclic compound AHR, PDGFRA, PDGFRB CYP1A2 175/4885CYP2A6 480/4885HTR2A 214/4885
US-20240208999-A1 HETEROCYCLIC COMPOUND AHR, PDGFRA, PDGFRB CYP1A2 175/4885CYP2A6 480/4885HTR2A 214/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.