SCHEMBL29403355

SCHEMBL29403355

N[C@@H](Cc1c[nH]c2ccc(Cl)cc12)C(=O)O

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ HTR2A P28223 4/20 0.73
▸ KMT2A Q03164 3/20 0.73
▸ KDM4E B2RXH2 2/20 0.73
▸ LMNA P02545 2/20 0.73
▸ MAPT P10636 2/20 0.73
▸ TSHR P16473 2/20 0.73
▸ BLM P54132 2/20 0.73
▸ PMP22 Q01453 2/20 0.73
▸ ALDH1A1 P00352 1/20 0.73
▸ CYP3A4 P08684 1/20 0.73
▸ HTR1A P08908 1/20 0.73
▸ ADORA3 P0DMS8 1/20 0.73
▸ ALOX15 P16050 1/20 0.73
▸ NFKB1 P19838 1/20 0.73
▸ HTR2C P28335 1/20 0.73
▸ SLC6A4 P31645 1/20 0.73
▸ HTR7 P34969 1/20 0.73
▸ HTR2B P41595 1/20 0.73
▸ MTOR P42345 1/20 0.73
▸ NPSR1 Q6W5P4 1/20 0.73

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL195273 1.00 HTR2A (0.73) HTR2AKMT2AKDM4ELMNAMAPT
SCHEMBL195272 1.00 HTR2A (0.73) HTR2AKMT2AKDM4ELMNAMAPT
SCHEMBL21309683 1.00 HTR2A (0.73) HTR2AKMT2AKDM4ELMNAMAPT
SCHEMBL31642414 1.00 HTR2A (0.73) HTR2AKMT2AKDM4ELMNAMAPT
Dl-Tryptophan SCHEMBL11375109 0.94 KMT2A (0.78) HTR2AKMT2AKDM4ELMNAMAPT
Tryptophan SCHEMBL11375111 0.94 KMT2A (0.78) HTR2AKMT2AKDM4ELMNAMAPT
SCHEMBL28473837 0.93 HTR2A (0.64) HTR2AKMT2AKDM4ELMNAMAPT
SCHEMBL28473836 0.93 HTR2A (0.64) HTR2AKMT2AKDM4ELMNAMAPT
SCHEMBL18029175 0.89 KMT2A (0.66) HTR2AKMT2AKDM4ELMNAMAPT
SCHEMBL456668 0.89 KMT2A (0.66) HTR2AKMT2AKDM4ELMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260077073-A1 GASTRIN-RELEASING PEPTIDE RECEPTOR (GRPR)-TARGETED COMPOUNDS AND USES THEREOF ALPHA 9 ONCOLOGY INC (CA) 2026-03-19 — — US claimed
WO-2025109003-A1 P-CADHERIN LIGANDS 3B PHARMACEUTICALS GMBH (DE) 2025-05-30 — — WO claimed
EP-4727655-A1 DLL3 TARGETING PEPTIDES AND CONSTRUCTS THEREOF Mariana Oncology Inc. (US) 2026-04-22 — — EP disclosed
EP-4727653-A1 DLL3 TARGETING PEPTIDES AND CONSTRUCTS THEREOF Mariana Oncology Inc. (US) 2026-04-22 — — EP disclosed
US-20260077073-A1 GASTRIN-RELEASING PEPTIDE RECEPTOR (GRPR)-TARGETED COMPOUNDS AND USES THEREOF ALPHA 9 ONCOLOGY INC (CA) 2026-03-19 — — US disclosed
WO-2025245483-A1 METHODS AND COMPOSITIONS FLAGSHIP PIONEERING INNOVATIONS VII, LLC (US) 2025-11-27 — — WO disclosed
US-20250361273-A1 METHODS AND COMPOSITIONS FLAGSHIP PIONEERING INNOVATIONS VII, LLC 2025-11-27 — — US disclosed
US-20250339569-A1 CARBONIC ANHYDRASE IX LIGANDS 3B PHARMACEUTICALS GMBH (DE) 2025-11-06 — — US disclosed
EP-3746467-B1 MODIFIED LIPIDATED RELAXIN B CHAIN PEPTIDES AND THEIR THERAPEUTIC USE SANOFI SA (FR) 2025-10-08 — — EP disclosed
US-20250296971-A1 GASTRIC INHIBITORY PEPTIDE RECEPTOR LIGANDS 3B PHARMACEUTICALS GMBH (DE) 2025-09-25 — — US disclosed
US-20250296959-A1 B7-H3 TARGETING PEPTIDES AND CONSTRUCTS THEREOF MARIANA ONCOLOGY INC (US) 2025-09-25 — — US disclosed
US-20230119612-A1 PEPTIDOMIMETIC MACROCYCLES AILERON THERAPEUTICS, INC. 2023-04-20 — — US disclosed
US-11629171-B2 Beta-hairpin peptidomimetics SPEXIS AG (CH) 2023-04-18 — — US disclosed
WO-2023036842-A1 TRANSMEMBRANE PEPTIDIC ANTAGONISTS OF PLEXIN-A1 AND THEIR THERAPEUTIC USES UNIVERSITE DE STRASBOURG (FR) 2023-03-16 — — WO disclosed
EP-4146629-A1 DIMERS FOR USE IN SYNTHESIS OF PEPTIDOMIMETICS The Feinstein Institutes for Medical Research (US) 2023-03-15 — — EP disclosed
US-20220290196-A1 GENETICALLY ENGINEERED MICROBES AND BIOSYNTHETIC METHODS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2022-09-15 — — US disclosed
WO-2022177635-A2 COMPOSITIONS AND METHODS FOR MICROBIAL DISEASE TREATMENT RA PHARMACEUTICALS, INC. (US) 2022-08-25 — — WO disclosed
WO-2022081721-A1 NANOMATERIAL AND METHODS OF USE THEREOF UNIVERSITY OF CONNECTICUT (US) 2022-04-21 — — WO disclosed
EP-3966223-A1 PEPTIDOMIMETIC AGENTS, SYNTHESIS AND USES THEREOF The Feinstein Institutes for Medical Research (US) 2022-03-16 — — EP disclosed
EP-3966201-A1 THIOSEMICARBAZATES AND USES THEREOF The Feinstein Institutes for Medical Research (US) 2022-03-16 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250296971-A1 GASTRIC INHIBITORY PEPTIDE RECEPTOR LIGANDS GIPR, VIP, GRPR HTR2A 1408/4885KMT2A 3863/4885KDM4E 4464/4885
US-20230119612-A1 PEPTIDOMIMETIC MACROCYCLES TP53, MDM2, MDM4 HTR2A 3792/4885KMT2A 2469/4885KDM4E 4446/4885
US-20250296959-A1 B7-H3 TARGETING PEPTIDES AND CONSTRUCTS THEREOF CD274, CD44, CD74 HTR2A 2747/4885KMT2A 322/4885KDM4E 1615/4885
US-20250339569-A1 CARBONIC ANHYDRASE IX LIGANDS CA9, CA13, CA4 HTR2A 4753/4885KMT2A 3777/4885KDM4E 2877/4885
US-20250361273-A1 METHODS AND COMPOSITIONS MC4R, GPR119, MC2R HTR2A 219/4885KMT2A 3419/4885KDM4E 2986/4885
US-11629171-B2 Beta-hairpin peptidomimetics POLL, POLQ, HBZ HTR2A 4856/4885KMT2A 2109/4885KDM4E 3552/4885
US-20260077073-A1 GASTRIN-RELEASING PEPTIDE RECEPTOR (GRPR)-TARGETED COMPOUNDS AND USES THEREOF GRPR, GIPR, GLP1R HTR2A 126/4885KMT2A 4091/4885KDM4E 4638/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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