SCHEMBL29403545

SCHEMBL29403545

Brc1cccc(-c2ccccc2)c1-c1cccs1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.48
MAPK1 P28482 1/20 0.48
ALOX5 P09917 1/20 0.38
ADORA2A P29274 5/20 0.38
ADORA1 P30542 4/20 0.38
CYP3A4 P08684 2/20 0.37
CYP2C9 P11712 2/20 0.37
LTA4H P09960 2/20 0.37
CYP2E1 P05181 1/20 0.37
CYP2A6 P11509 1/20 0.37
CYP2B6 P20813 1/20 0.37
KDM4E B2RXH2 4/20 0.36
MAPT P10636 3/20 0.36
MEN1 O00255 3/20 0.36
KMT2A Q03164 3/20 0.36
HPGD P15428 2/20 0.36
ACHE P22303 1/20 0.36
CYP1A2 P05177 1/20 0.36
CYP2C19 P33261 1/20 0.36
PPARG P37231 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30332910 0.87 ALOX5 (0.43) ALDH1A1ALOX5ADORA2AADORA1CYP3A4
SCHEMBL1334679 0.85 LTK (0.41) ALDH1A1ADORA2AADORA1CYP3A4CYP2C9
Hydrogen Sulfide SCHEMBL27738387 0.85 ALOX5 (0.42) ALDH1A1ALOX5ADORA2AADORA1CYP3A4
SCHEMBL5229701 0.81 MAPT (0.46) ALDH1A1CYP3A4CYP2C9LTA4HCYP2E1
SCHEMBL27891520 0.80 ALOX5 (0.48) ALDH1A1ALOX5ADORA2AADORA1CYP3A4
SCHEMBL27912112 0.79 KDM4E (0.46) ALDH1A1MAPK1ALOX5ADORA2AADORA1
Hydrogen Sulfide SCHEMBL27718513 0.79 ALOX5 (0.47) ALDH1A1ALOX5ADORA2AADORA1CYP3A4
SCHEMBL28469645 0.78 ADORA2A (0.40) ALDH1A1ALOX5ADORA2AADORA1CYP3A4
SCHEMBL27510656 0.77 LTA4H (0.53) ALDH1A1ADORA2AADORA1CYP3A4CYP2C9
SCHEMBL7525871 0.77 ALDH1A1 (0.65) ALDH1A1MAPK1CYP2A6MAPTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108112250-B Compound for organic electric element, organic electric element using same, and electronic device using same 德山新勒克斯有限公司 2022-02-25 CN disclosed