SCHEMBL29403663

SCHEMBL29403663

COc1cc(CCl)cc2ccsc12

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TTR P02766 2/20 0.40
ALDH1A1 P00352 6/20 0.38
KDM4E B2RXH2 4/20 0.38
TDP1 Q9NUW8 3/20 0.38
MAPT P10636 2/20 0.37
LMNA P02545 1/20 0.37
PPARG P37231 1/20 0.37
GFER P55789 1/20 0.37
NCOA2 Q15596 1/20 0.37
NCOA1 Q15788 1/20 0.37
RXFP1 Q9HBX9 1/20 0.37
HTR2A P28223 2/20 0.36
HTR2C P28335 2/20 0.36
TSHR P16473 1/20 0.36
KEAP1 Q14145 1/20 0.36
PDE10A Q9Y233 1/20 0.36
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
CA2 P00918 1/20 0.35
RAB9A P51151 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22315354 1.00 TTR (0.40) TTRALDH1A1KDM4ETDP1MAPT
SCHEMBL30395946 0.87 PDE4A (0.38) MAPTLMNAHTR2AHTR2CTSHR
SCHEMBL22607007 0.87 PDE4A (0.38) MAPTLMNAHTR2AHTR2CTSHR
SCHEMBL15018567 0.75 ACHE (0.43) ALDH1A1MAPTHTR2AHTR2CTSHR
SCHEMBL4803345 0.75 MAPT (0.40) ALDH1A1MAPTRXFP1HTR2AHTR2C
SCHEMBL10368828 0.75 CA12 (0.42) TTRALDH1A1KDM4ETDP1MAPT
SCHEMBL21438629 0.74 CYP2A6 (0.34) HTR2AHTR2C
SCHEMBL30396380 0.73 CYP2A6 (0.32)
SCHEMBL14673728 0.71 MAPT (0.41) ALDH1A1KDM4EMAPTGFERHTR2A
SCHEMBL10725852 0.70 PDGFRB (0.39) ALDH1A1KDM4EMAPTRXFP1HTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220356194-A1 PROCESS FOR PREPARING BENZOTHIOPHEN-2YL BORONATE BAYER PHARMA AKTIENGESELLSCHAFT (DE) 2022-11-10 US disclosed
US-11274110-B2 Process for preparing benzothiophen-2yl boronate BAYER PHARMA AKTIENGESELLSCHAFT (DE) 2022-03-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220356194-A1 PROCESS FOR PREPARING BENZOTHIOPHEN-2YL BORONATE BPGM, BRCA1, BRAP TTR 736/4885ALDH1A1 1918/4885KDM4E 1509/4885
US-11274110-B2 Process for preparing benzothiophen-2yl boronate BPGM, BRCA1, BRAP TTR 736/4885ALDH1A1 1918/4885KDM4E 1509/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.