Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.38 |
| ▸ | ACHE | P22303 | 3/20 | 0.34 |
| ▸ | BCHE | P06276 | 2/20 | 0.34 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16504486 | 0.90 | MAPT (0.39) | MAPTNPSR1PTGS2ACHEBCHE | |
| SCHEMBL16504487 | 0.90 | MAPT (0.39) | MAPTNPSR1PTGS2ACHEBCHE | |
| SCHEMBL29404544 | 0.79 | MAPT (0.46) | MAPTHTTKMT2AHCAR3NPC1 | |
| SCHEMBL11140206 | 0.75 | MAPK1 (0.50) | MAPTNPSR1PTGS2KMT2AHCAR3 | |
| SCHEMBL29406597 | 0.75 | GAA (0.38) | MAPTHTTKMT2AHCAR3LMNA | |
| SCHEMBL7092393 | 0.74 | NPC1 (0.42) | MAPTNPSR1HTTKMT2ANPC1 | |
| SCHEMBL11744519 | 0.74 | TSHR (0.51) | MAPTNPSR1PTGS2HTTKMT2A | |
| SCHEMBL585617 | 0.74 | ALDH1A1 (0.49) | MAPTNPSR1PTGS2CRHR1HTT | |
| SCHEMBL11875032 | 0.74 | VCAM1 (0.53) | MAPTNPSR1HTTLMNAALDH1A1 | |
| SCHEMBL14253769 | 0.73 | MEN1 (0.49) | MAPTKMT2ALMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022053567-A1 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS | SYNGENTA CROP PROTECTION AG (CH) | 2022-03-17 | — | — | WO | disclosed |