Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRNP | P04156 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | F2R | P25116 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | FABP4 | P15090 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28510287 | 0.87 | ALDH1A1 (0.48) | KMT2AMEN1HPGDALDH1A1ALOX15 | |
| SCHEMBL241422 | 0.81 | PRNP (0.56) | PRNPKMT2AHPGDALDH1A1ALOX15 | |
| SCHEMBL29540504 | 0.81 | PRNP (0.56) | PRNPKMT2AHPGDALDH1A1ALOX15 | |
| SCHEMBL29480937 | 0.80 | TSHR (0.56) | KMT2AF2RMEN1HPGDALDH1A1 | |
| SCHEMBL28808058 | 0.79 | ALDH1A1 (0.44) | KMT2AHPGDALDH1A1ALOX15HSD17B10 | |
| SCHEMBL6272437 | 0.79 | PRNP (0.47) | PRNPKMT2AHPGDALDH1A1ALOX15 | |
| SCHEMBL28652440 | 0.78 | CA12 (0.54) | PRNPKMT2AF2RMEN1HPGD | |
| SCHEMBL27721559 | 0.76 | CES2 (0.47) | KMT2AF2RMEN1HPGDALDH1A1 | |
| SCHEMBL31582514 | 0.76 | PRNP (0.45) | PRNPKMT2AHPGDALDH1A1ALOX15 | |
| SCHEMBL27596818 | 0.76 | F2R (0.46) | PRNPKMT2AF2RMEN1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114174278-B | Dihydroorotate dehydrogenase inhibitors | 詹森生物科技公司 | 2024-08-23 | — | — | CN | disclosed |
| CN-114174278-A | Dihydroorotate dehydrogenase inhibitors | 詹森生物科技公司 | 2022-03-11 | — | — | CN | disclosed |
| EP-3956320-A1 | DIHYDROOROTATE DEHYDROGENASE INHIBITORS | Janssen Biotech, Inc. (US) | 2022-02-23 | — | — | EP | disclosed |