Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRNP | P04156 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | CA4 | P22748 | 2/20 | 0.46 |
| ▸ | CA7 | P43166 | 2/20 | 0.46 |
| ▸ | CA9 | Q16790 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | FABP4 | P15090 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL241422 | 0.85 | PRNP (0.56) | PRNPCA12CA1CA2CA4 | |
| SCHEMBL29540504 | 0.85 | PRNP (0.56) | PRNPCA12CA1CA2CA4 | |
| SCHEMBL15049648 | 0.85 | ALDH1A1 (0.55) | CA12CA1CA2CA4CA7 | |
| SCHEMBL31582514 | 0.85 | PRNP (0.45) | PRNPCA12CA1CA2CA4 | |
| SCHEMBL11846322 | 0.83 | THRB (0.54) | CA12CA1CA2CA7CA9 | |
| SCHEMBL2953498 | 0.81 | ALDH1A1 (0.50) | CA12CA1CA2CA4CA7 | |
| SCHEMBL29404196 | 0.79 | PRNP (0.44) | PRNPCA12CA1CA2CA4 | |
| SCHEMBL29401587 | 0.79 | PRNP (0.44) | PRNPCA12CA1CA2CA4 | |
| SCHEMBL2549837 | 0.78 | AKR1C3 (0.59) | PRNPALDH1A1ALOX15FABP4KDM4E | |
| SCHEMBL7280223 | 0.78 | ALDH1A1 (0.59) | CA12CA1CA2CA4CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1224467-B1 | PROTECTING ALKYLATING REAGENTS USED FOR QUANTIFYING HOMOCYSTEINE | DADE BEHRING MARBURG GMBH (DE) | 2005-11-30 | — | — | EP | disclosed |
| CN-1080720-C | Thiazole derivatives | HOFFMANN LA ROCHE (CH) | 2002-03-13 | — | — | CN | disclosed |
| CN-1224718-A | Thiazole derivatives | HOFFMANN LA ROCHE (CH) | 1999-08-04 | — | — | CN | disclosed |