SCHEMBL29404281

SCHEMBL29404281

c1ccc2sc(SN3CCOCC3)nc2c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 1.00
HSD17B10 Q99714 5/20 1.00
HPGD P15428 3/20 1.00
ALOX15 P16050 3/20 1.00
PKM P14618 3/20 1.00
KDM4E B2RXH2 2/20 1.00
SMN1; SMN2 Q16637 4/20 0.57
NPC1 O15118 4/20 0.57
RAB9A P51151 4/20 0.57
MAPK1 P28482 2/20 0.57
LMNA P02545 2/20 0.55
ADRA2A P08913 1/20 0.53
FBP1 P09467 1/20 0.53
ADORA3 P0DMS8 1/20 0.53
DRD2 P14416 1/20 0.53
ADRA2B P18089 1/20 0.53
ADRA2C P18825 1/20 0.53
DRD1 P21728 1/20 0.53
MC5R P33032 1/20 0.53
OPRM1 P35372 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL79658 1.00 ALDH1A1 (1.00) ALDH1A1HSD17B10HPGDALOX15PKM
SCHEMBL7937684 0.89 ALDH1A1 (0.79) ALDH1A1HSD17B10HPGDALOX15PKM
SCHEMBL8203421 0.89 ALDH1A1 (0.79) ALDH1A1HSD17B10HPGDALOX15PKM
SCHEMBL2187148 0.87 ALDH1A1 (0.75) ALDH1A1HSD17B10HPGDALOX15PKM
SCHEMBL1412338 0.86 ALDH1A1 (0.75) ALDH1A1HSD17B10HPGDALOX15PKM
SCHEMBL30514153 0.86 ALDH1A1 (0.75) ALDH1A1HSD17B10HPGDALOX15PKM
SCHEMBL637062 0.85 ALDH1A1 (0.74) ALDH1A1HSD17B10HPGDALOX15PKM
SCHEMBL29392402 0.85 ALDH1A1 (0.74) ALDH1A1HSD17B10HPGDALOX15PKM
SCHEMBL11545638 0.84 ALDH1A1 (0.73) ALDH1A1HSD17B10HPGDALOX15PKM
SCHEMBL10794271 0.84 ALDH1A1 (0.73) ALDH1A1HSD17B10HPGDALOX15PKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114315758-A Synthesis method of vulcanization accelerator 2- (morpholinothio) benzothiazole 上海应用技术大学 2022-04-12 CN claimed
EP-4677023-A1 RUBBER COMPOSITION COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) 2026-01-14 EP disclosed
EP-4453084-A1 RUBBER SHEET COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) 2024-10-30 EP disclosed
WO-2024184337-A1 RUBBER COMPOSITION COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) 2024-09-12 WO disclosed
CN-118591587-A Rubber sheet 米其林集团总公司 2024-09-03 CN disclosed
CN-111320733-B Block copolymers and their use 科腾聚合物有限责任公司 2024-08-16 CN disclosed
CN-118355068-A Rubber composition 米其林集团总公司 2024-07-16 CN disclosed
CN-118302480-A Rubber composition 米其林集团总公司 2024-07-05 CN disclosed
CN-118251314-A Rubber composition 米其林集团总公司 2024-06-25 CN disclosed
CN-118159428-A Rubber composition 米其林集团总公司 2024-06-07 CN disclosed
CN-112986416-B Multi-component large-flux detection method for plastic additive in atmospheric particulates 暨南大学 2022-09-30 CN disclosed
EP-3408329-B1 METHOD FOR TESTING THE IN SITU SILANIZATION OF LIGHT FILLERS LANXESS DEUTSCHLAND GMBH (DE) 2022-09-21 EP disclosed
CN-110573537-B Graft polymers for dispersing graphene and graphite 埃克森美孚化学专利公司 2022-05-03 CN disclosed
EP-3983202-A1 3D-PRINTING METHODS AND SYSTEMS Bostik SA (FR) 2022-04-20 EP disclosed
CN-114315758-A Synthesis method of vulcanization accelerator 2- (morpholinothio) benzothiazole 上海应用技术大学 2022-04-12 CN disclosed
CN-114315758-A Synthesis method of vulcanization accelerator 2- (morpholinothio) benzothiazole 上海应用技术大学 2022-04-12 CN disclosed
CN-114315758-A Synthesis method of vulcanization accelerator 2- (morpholinothio) benzothiazole 上海应用技术大学 2022-04-12 CN disclosed
WO-2022066217-A1 RUBBER COMPOSITION FOR NON-PNEUMATIC SUPPORT COMPONENTS BRIDGESTONE AMERICAS TIRE OPERATIONS, LLC (US) 2022-03-31 WO disclosed
CN-114126838-A 3D printing method and system 波士胶公司 2022-03-01 CN disclosed
CN-106661734-B Method for manufacturing circuit board and circuit board manufactured by the same 上村工业株式会社 2022-02-25 CN disclosed