SCHEMBL79658

SCHEMBL79658

c1ccc2sc(SN3CCOCC3)nc2c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 1.00
HSD17B10 Q99714 5/20 1.00
HPGD P15428 3/20 1.00
ALOX15 P16050 3/20 1.00
PKM P14618 3/20 1.00
KDM4E B2RXH2 2/20 1.00
SMN1; SMN2 Q16637 4/20 0.57
NPC1 O15118 4/20 0.57
RAB9A P51151 4/20 0.57
MAPK1 P28482 2/20 0.57
LMNA P02545 2/20 0.55
ADRA2A P08913 1/20 0.53
FBP1 P09467 1/20 0.53
ADORA3 P0DMS8 1/20 0.53
DRD2 P14416 1/20 0.53
ADRA2B P18089 1/20 0.53
ADRA2C P18825 1/20 0.53
DRD1 P21728 1/20 0.53
MC5R P33032 1/20 0.53
OPRM1 P35372 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29404281 1.00 ALDH1A1 (1.00) ALDH1A1HSD17B10HPGDALOX15PKM
SCHEMBL7937684 0.89 ALDH1A1 (0.79) ALDH1A1HSD17B10HPGDALOX15PKM
SCHEMBL8203421 0.89 ALDH1A1 (0.79) ALDH1A1HSD17B10HPGDALOX15PKM
SCHEMBL2187148 0.87 ALDH1A1 (0.75) ALDH1A1HSD17B10HPGDALOX15PKM
SCHEMBL1412338 0.86 ALDH1A1 (0.75) ALDH1A1HSD17B10HPGDALOX15PKM
SCHEMBL30514153 0.86 ALDH1A1 (0.75) ALDH1A1HSD17B10HPGDALOX15PKM
SCHEMBL637062 0.85 ALDH1A1 (0.74) ALDH1A1HSD17B10HPGDALOX15PKM
SCHEMBL29392402 0.85 ALDH1A1 (0.74) ALDH1A1HSD17B10HPGDALOX15PKM
SCHEMBL11545638 0.84 ALDH1A1 (0.73) ALDH1A1HSD17B10HPGDALOX15PKM
SCHEMBL10794271 0.84 ALDH1A1 (0.73) ALDH1A1HSD17B10HPGDALOX15PKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2085 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4408919-B1 SULFUR-CURABLE RUBBER COMPOSITION CONTAINING ORGANIC FILLERS AND ORGANOSILANE SUNCOAL IND GMBH (DE) 2025-10-29 EP claimed
US-20250215132-A1 TWO-PART CURABLE COMPOSITION BOSTIK SA (FR) 2025-07-03 US claimed
EP-4504844-A1 TWO-PART CURABLE COMPOSITION Bostik SA (FR) 2025-02-12 EP claimed
US-20240392113-A1 SULFUR-CROSSLINKABLE RUBBER COMPOSITION CONTAINING ORGANIC FILLERS AND ORGANOSILANE SUNCOAL INDUSTRIES GMBH (DE) 2024-11-28 US claimed
CN-118755159-B Heat-stable inner tube material and preparation method thereof 南通顺驰橡胶制品有限公司 2024-11-22 CN claimed
CN-118978754-A Full-hot-melt tread rubber polymer with ultrahigh grip under low temperature condition 安徽佳通乘用子午线轮胎有限公司 2024-11-19 CN claimed
CN-118755159-A Heat-stable inner tube material and preparation method thereof 南通顺驰橡胶制品有限公司 2024-10-11 CN claimed
CN-118702975-A Tire tread rubber composition with normal-temperature low rolling resistance and low-temperature low rolling resistance, preparation method thereof and tire 安徽佳通乘用子午线轮胎有限公司 2024-09-27 CN claimed
EP-4408919-A1 SULFUR-CROSSLINKABLE RUBBER COMPOSITION CONTAINING ORGANIC FILLERS AND ORGANOSILANE SunCoal Industries GmbH (DE) 2024-08-07 EP claimed
CN-118255716-A Novel phenyl quinolone compound with antibacterial and anticancer functions and preparation thereof 深圳阿尔法分子科技有限责任公司 2024-06-28 CN claimed
US-4581297-A STEEL BELTED RADIAL TIRES MONSANTO EUROPE, S.A. (BE) 1986-04-08 US claimed
EP-0175669-A2 Rubber/metal composites MONSANTO EUROPE S.A./N.V. (BE) 1986-03-26 EP claimed
EP-0150168-A2 Use of metal salts of thiosulphuric -S-esters as rubber/metal bonding promoters MONSANTO EUROPE S.A./N.V. (BE) 1985-07-31 EP claimed
EP-0109955-A2 Rubber/metal composites MONSANTO EUROPE S.A./N.V. (BE) 1984-05-30 EP claimed
EP-0054868-A1 Process for the production of granules from organic molten material BAYER AG (DE) 1982-06-30 EP claimed
US-4063787-A Cylindrical, flexible bearings THIOKOL CORPORATION (US) 1977-12-20 US claimed
US-4011247-A METHOD FOR THE PREPARATION OF AN ORGANOHYDROGENPOLYSILOXANE AS A PRODUCT OF A PARTIAL ADDITION REACTION SHINETSU CHEMICAL COMPANY (JA) 1977-03-08 US claimed
US-4002594-A THIOMORPHOLINE PPG INDUSTRIES, INC. (US) 1977-01-11 US claimed
US-3969350-A Base catalysis of azolesulfenamides and sulfur to aminodithioazoles MONSANTO COMPANY (US) 1976-07-13 US claimed
US-3965077-A VULCANIZATION RETARDERS THE B. F. GOODRICH COMPANY (US) 1976-06-22 US claimed