Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.75 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.75 |
| ▸ | HPGD | P15428 | 4/20 | 0.75 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.75 |
| ▸ | PKM | P14618 | 2/20 | 0.75 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.75 |
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.45 |
| ▸ | NPC1 | O15118 | 4/20 | 0.45 |
| ▸ | RAB9A | P51151 | 4/20 | 0.45 |
| ▸ | USP2 | O75604 | 2/20 | 0.42 |
| ▸ | RECQL | P46063 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | FBP1 | P09467 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29404281 | 0.87 | ALDH1A1 (1.00) | ALDH1A1HSD17B10HPGDALOX15PKM | |
| SCHEMBL79658 | 0.87 | ALDH1A1 (1.00) | ALDH1A1HSD17B10HPGDALOX15PKM | |
| SCHEMBL80374 | 0.83 | ALDH1A1 (0.58) | ALDH1A1HSD17B10HPGDALOX15KDM4E | |
| SCHEMBL29370541 | 0.83 | ALDH1A1 (0.58) | ALDH1A1HSD17B10HPGDALOX15KDM4E | |
| SCHEMBL6372950 | 0.81 | ALDH1A1 (0.56) | ALDH1A1HSD17B10HPGDALOX15KDM4E | |
| SCHEMBL30017383 | 0.81 | ALDH1A1 (0.56) | ALDH1A1HSD17B10HPGDALOX15KDM4E | |
| SCHEMBL6915262 | 0.81 | ALDH1A1 (0.69) | ALDH1A1HSD17B10HPGDALOX15PKM | |
| Tert-Butylamine SCHEMBL11814397 | 0.80 | ALDH1A1 (0.54) | ALDH1A1HSD17B10HPGDALOX15KDM4E | |
| SCHEMBL16454553 | 0.79 | ALDH1A1 (0.72) | ALDH1A1HSD17B10HPGDALOX15PKM | |
| SCHEMBL7937684 | 0.77 | ALDH1A1 (0.79) | ALDH1A1HSD17B10HPGDALOX15PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2346956-A1 | ACTIVATORS FOR TWO PART CYANOACRYLATE ADHESIVES | Loctite (R & D) Limited (IE) | 2011-07-27 | — | — | EP | disclosed |
| WO-2010046412-A1 | ACTIVATORS FOR TWO PART CYANOACRYLATE ADHESIVES | LOCTITE (R & D) LIMITED (IE) | 2010-04-29 | — | — | WO | disclosed |