Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | TPSAB1 | Q15661 | 3/20 | 0.48 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.47 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.47 |
| ▸ | MME | P08473 | 1/20 | 0.46 |
| ▸ | ECE1 | P42892 | 1/20 | 0.46 |
| ▸ | CTSB | P07858 | 3/20 | 0.45 |
| ▸ | CTSK | P43235 | 3/20 | 0.45 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.45 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | AR | P10275 | 1/20 | 0.43 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29918749 | 0.91 | ALDH1A1 (0.49) | KDM4EMEN1ALDH1A1LMNAHPGD | |
| SCHEMBL29601597 | 0.89 | SIRT2 (0.51) | KDM4EMEN1ALDH1A1HPGDKMT2A | |
| SCHEMBL20660119 | 0.89 | SIRT2 (0.51) | KDM4EMEN1ALDH1A1HPGDKMT2A | |
| SCHEMBL7541299 | 0.88 | KDM4E (0.56) | KDM4EMEN1ALDH1A1LMNAHPGD | |
| SCHEMBL29357202 | 0.87 | SIRT1 (0.53) | KDM4EALDH1A1HPGDTPSAB1SIRT2 | |
| SCHEMBL30141948 | 0.86 | SIRT2 (0.49) | KDM4EMEN1ALDH1A1LMNAHPGD | |
| SCHEMBL29791017 | 0.86 | SIRT2 (0.49) | KDM4EMEN1ALDH1A1LMNAHPGD | |
| SCHEMBL7740151 | 0.86 | KDM4E (0.59) | KDM4EMEN1ALDH1A1LMNAHPGD | |
| Hydrochloric Acid SCHEMBL22413023 | 0.86 | SIRT2 (0.48) | TPSAB1SIRT2SIRT1MMEECE1 | |
| Hydrochloric Acid SCHEMBL31755364 | 0.86 | SIRT2 (0.48) | TPSAB1SIRT2SIRT1MMEECE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024197174-A1 | PEPTIDE SUBSTRATES AND INHIBITORS OF CATHEPSIN B | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2024-09-26 | — | — | WO | disclosed |
| WO-2024030500-A1 | COMPOSITIONS AND METHODS FOR TREATING PANCREATITIS | GUKOVSKAYA ANNA (US) | 2024-02-08 | — | — | WO | disclosed |
| EP-4294802-A1 | CRYPTOPHYCIN COMPOUNDS AND CONJUGATES THEREOF | Universität Bielefeld (DE) | 2023-12-27 | — | — | EP | disclosed |
| WO-2022175222-A1 | CRYPTOPHYCIN COMPOUNDS AND CONJUGATES THEREOF | UNIVERSITÄT BIELEFELD (DE) | 2022-08-25 | — | — | WO | disclosed |
| CN-114177199-A | Polypeptide-modified gold cluster and application of polypeptide-modified gold cluster in resisting tumor invasion and metastasis by inhibiting activity of cathepsin B | 北京工业大学 | 2022-03-15 | — | — | CN | disclosed |