Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 4/20 | 0.60 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.60 |
| ▸ | ALB | P02768 | 2/20 | 0.60 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.60 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.60 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.60 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.60 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.60 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.60 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.60 |
| ▸ | HTR2B | P41595 | 1/20 | 0.60 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.60 |
| ▸ | TSPO | P30536 | 2/20 | 0.43 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8288573 | 0.81 | GABRA1 (0.61) | GABRA1GABRB2ALBOPRK1KCNH2 | |
| SCHEMBL2932444 | 0.80 | GABRA1 (0.60) | GABRA1GABRB2ALBOPRK1KCNH2 | |
| SCHEMBL2935043 | 0.80 | GABRA1 (0.60) | GABRA1GABRB2ALBOPRK1KCNH2 | |
| SCHEMBL1761287 | 0.79 | GABRA1 (0.74) | GABRA1GABRB2ALBOPRK1KCNH2 | |
| SCHEMBL2929266 | 0.79 | GABRA1 (0.74) | GABRA1GABRB2ALBOPRK1KCNH2 | |
| SCHEMBL2934780 | 0.78 | GABRB2 (0.67) | GABRA1GABRB2ALBOPRK1KCNH2 | |
| SCHEMBL2929147 | 0.78 | GABRB2 (0.73) | GABRA1GABRB2ALBOPRK1KCNH2 | |
| SCHEMBL6011803 | 0.78 | GABRA1 (0.73) | GABRA1GABRB2ALBOPRK1KCNH2 | |
| SCHEMBL14797241 | 0.78 | GABRA1 (0.73) | GABRA1GABRB2ALBOPRK1KCNH2 | |
| SCHEMBL8286542 | 0.77 | GABRA1 (0.61) | GABRA1GABRB2ALBOPRK1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1682549-B1 | IMIDAZO[1,2-A]PYRIDINE ANXIOLYTICS | SEPRACOR INC (US) | 2010-09-22 | — | — | EP | claimed |
| WO-2005044818-A2 | IMIDAZO[1,2-A]PYRIDINE ANXIOLYTICS | SEPRACOR, INC. (US) | 2005-05-19 | — | — | WO | disclosed |